MFH2_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: MFH2_SCHPO
• UniProt AC: Q9HE09
• Protein Name: Putative ATP-dependent DNA helicase fml2
• Gene Name: fml2 {ECO:0000303|PubMed:18851838}
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 783
• Subcellular Localization: Nucleus, nucleolus .
• Protein Sequence: MIVLRDSSDYSDSEVDLPSIEVNGERGNVPTSVLCNVEGSLLNSNPALRQPNLKCIKHNQDVENTTFQLDLRGCRVPSSQPQVITELENNIDIPKNIDAMQNWIFPQTQQYRNYQKEFCEQALFHNLLLALPTGLGKTFIAAVVMLNYFRWFPESKIIFLAPTKPLLLQQRVACSNVAGMSPGATAELNGEVSPDRRLFEYNTKRVFFMTPQTLQNDLKEHLLDAKSIICLIFDEAHRATGNHSYAQVMRAVLRSNSHFRVLGLTATPGSSTASVQKVVDCLHISKLIVRNEESIDIRSYVFHKKIQLIKVTISSEMNILKSDFANLYRPYFNFLRQKKLIPINCECLNIKAYTLFVSLRKYSFSSKNVQSKEKSKIMSCFTLLISCAHITYLLDCHGIIQFYQKLVETKNKAEGKGSGQSFWLFTSKPFAFYLEHLHNKIQGLSLNHPKMNHLLELLKEHFKDTSEGYQNQRVMIFTEFRNTAEYITTTLLAIRPMVRASLFIGQANSAYSTGMNQMQQKETIDQFRAGVINTLVATSIGEEGLDIGDTDMIICYDASSSPIRTIQRMGRTGRKKSGKVFVLLTEDCEDSKWERSQVSYRRVQKVIESGKKIALKKDVPRLIPSNIQPIFKFQALQNNADATLILNSYNNNSSSLSPVNTLANQAHSRSKRYLPFIVDDVFEDMESNLRVPTEDAKIKRFKSDYRSCIYNARRNVFSKPTYMGDKLTKFAKVPHSLLTLSIYRRGRLLQQCSPSSVTKYLKYEEKFKRKRMKKTSNALFQST

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
7	Phosphorylation	-MIVLRDSSDYSDSE -CEEECCCCCCCCCC	20.76	25720772
10	Phosphorylation	VLRDSSDYSDSEVDL EECCCCCCCCCCCCC	19.14	25720772
11	Phosphorylation	LRDSSDYSDSEVDLP ECCCCCCCCCCCCCC	39.38	25720772
13	Phosphorylation	DSSDYSDSEVDLPSI CCCCCCCCCCCCCEE	33.31	25720772

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of MFH2_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of MFH2_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of MFH2_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
EME1_SCHPO	eme1	genetic	18818364
ABP1_SCHPO	cbp1	genetic	18818364
SAT1_SCHPO	sat1	genetic	18818364
DHE4_SCHPO	gdh1	genetic	22681890
HS104_SCHPO	hsp104	genetic	22681890
TAL1_SCHPO	tal1	genetic	22681890
HRP3_SCHPO	hrp3	genetic	22681890
CDA1_SCHPO	cda1	genetic	22681890
VTS1_SCHPO	SPBC13E7.03c	genetic	22681890
ILVB_SCHPO	ilv1	genetic	22681890
LDH_SCHPO	SPAC186.08c	genetic	22681890
NDK_SCHPO	ndk1	genetic	22681890
CTBL1_SCHPO	SPAC1952.06c	genetic	22681890
PFA3_SCHPO	pfa3	genetic	22681890
YN8E_SCHPO	SPBP35G2.14	genetic	22681890
GOS1_SCHPO	gos1	genetic	22681890
PUF3_SCHPO	puf3	genetic	22681890
YLO2_SCHPO	tma23	genetic	22681890
HRQ1_SCHPO	hrq1	genetic	22681890
PPR2_SCHPO	ppr2	genetic	22681890
SNF5_SCHPO	snf5	genetic	22681890
GLRX5_SCHPO	grx5	genetic	22681890
YJ83_SCHPO	SPCC330.03c	genetic	22681890
YAOG_SCHPO	SPAC11D3.16c	genetic	22681890
TRX2_SCHPO	trx2	genetic	22681890
PAN3_SCHPO	ppk26	genetic	22681890
CAO2_SCHPO	cao2	genetic	22681890
FSC1_SCHPO	fsc1	genetic	22681890
YKM8_SCHPO	SPAPB24D3.08c	genetic	22681890
YH05_SCHPO	SPBC1685.05	genetic	22681890
ATG17_SCHPO	atg17	genetic	22681890
YA7D_SCHPO	SPAC24H6.13	genetic	22681890
TYW4_SCHPO	SPBC19C7.08c	genetic	22681890
ACH1_SCHPO	SPAC1952.09c	genetic	22681890
SDE2_SCHPO	sde2	genetic	22681890
RHP9_SCHPO	crb2	genetic	22681890
YG0C_SCHPO	SPBC1604.12	genetic	22681890
EHS1_SCHPO	yam8	genetic	22681890
STG1_SCHPO	stg1	genetic	22681890
BGS4_SCHPO	bgs4	genetic	22681890
SGF29_SCHPO	sgf29	genetic	22681890
RAD5_SCHPO	rad8	genetic	24875629
MFH2_SCHPO	fml2	physical	26771498

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.