YH05_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: YH05_SCHPO
• UniProt AC: O74325
• Protein Name: PDZ domain-containing protein C1685.05
• Gene Name: SPBC1685.05
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 997
• Subcellular Localization: Cytoplasm .
• Protein Sequence: MTPVSSDYRPNHIFLPKFRPDKITSECNTPQQQNVIAEGLYNVSEPFPIRNTDEERYLDTKEIHHTWDNTIKNVVRSIVSIKGSALRSFDTESAGSFCATGFVVNKTLGLILSNRHVVSPGPISARASFINYEEIDIYPIYRDPVHDFGFFRYDPSSIRFHDVTEISLSPESAKVGIDIRIIGNDAGEKLSILSSTLARLDRPAPNYGIDNYNDFNTFYYQAASGTSGGSSGSPVLDISGAAVALNSGGSNSSASSFYLPLDRVVRALRCIENNTPITRGTLLTEFLHWSYDELSRIGLPREFEYDCRTRVPSSTGLLVVSRVLRNSEVSKALEPGDILIAFKTDSHKSTYIVDFVSLFEVLDEMVGKTIELHVYRPKRGFLTFQLTVQDLHNVTPSRFLEVGGAVLHDLSYQLARSYQFSLNSGTYVASSGMLNWSSGTRDFLVTRLANKPTPTLDAFIDVLVQLTDNARVPMHFRVLGKYEEEFTIVTVDRHFFLASIFSRNDEKGTWDRQSLPPPQPSISRRPSVIPRPQEGSKSMEAIQNALVLVHCRMPYSINGFSSTKLYSGTGVIVSVVPPLIVVDRSVIPVDICDIRLTFQSMSAMGHLTFLDNRIAVVSCDYLPSNSVQLNFVADFLRTGDECTLAALDEDLQLLTKKTTVRSVSVVETERSSPPRFRYVNCEVISLMDSLASTGGLVFREVGDDREIVALWISVVHQDVGGKDYTTKYGLSMSYILPVLERLKLPPSARAQHVPTTAGVEWSHITLAGASTLGLSQTRSSEFYMKSRENGTIPRPLYVISHLRPLLHKTSLGVGDILLEVNGKMITRLSDLHEFETESEIKAVILRDGIEMEITIPLYPEYPTFSSRAICWMGAIIHPTHSSVFEQVEPDVDLPGPEGVYVGSILYGSPALNMLRAAHWIVAVDGHDINTFDDFYHMLLEKPTDTFVQVKQMNRRGATSIVSVRPDPLFWPTCIIERDSNGRWCTKHLQRKTKEVCS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
24	Phosphorylation	KFRPDKITSECNTPQ CCCCCCCCCCCCCHH	24.98	29996109
25	Phosphorylation	FRPDKITSECNTPQQ CCCCCCCCCCCCHHH	43.56	29996109
29	Phosphorylation	KITSECNTPQQQNVI CCCCCCCCHHHHCCC	33.85	25720772
527	Phosphorylation	PSISRRPSVIPRPQE CCCCCCCCCCCCCCC	30.76	28889911

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of YH05_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of YH05_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of YH05_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
YH05_SCHPO	SPBC1685.05	physical	26771498
PPK21_SCHPO	ppk21	physical	26771498
LIN1_SCHPO	lin1	physical	26771498

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.