FSC1_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: FSC1_SCHPO
• UniProt AC: O94439
• Protein Name: FAS1 domain-containing protein fsc1
• Gene Name: fsc1
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 728
• Subcellular Localization: Vacuole membrane ; Single-pass type I membrane protein .
• Protein Description: Required for the fusion of autophagosomes with the vacuole..
• Protein Sequence: MNLQFRLYLLFILLFISFANGKNEYEDKSTSIIDLLSSKSQFSKLIRRLQRNRLVPYLNRNKGLTLFAPLNEAFPDDSIEPNLLYYIVNTTELDRSVLRTQLKSSDGQQIALKIHYKAETGRAYDKVNNAQIVQSNWRADSGVVQVIDNIIDLPPPALEILSSEKDFSIFHRLSVAWVGEYSSVTMLVPDSSAFLNVYTNTELAYLYSMYAAEDVKTLIHQHILVNQRVYAEDVIEPKTFHYKNGISISMKFDKDQKKLFINDVSTTKYDLLTFSGAIHTVSSLINPEIISFTPAKYLIGIGAAWFSEKLSRERKSISVDKTSKRAILAPTNWAYREIIDIDYHIIENFDLPAPNKYALYVTNIKSGNSVGEDTNALVRIATGSAGEMYVNVETRSIQSENIGNVSLYVLDKDIEPPQPLLSQLILVDEISFSVRYLASLGLGDYTKVTWFLVKNSAWTQLGLVHLVLQQNLELLESVMLDYAFEGIAFYGSSDEAWASGNYTTLSNKEFLIEGVYEDSNSRNKRDLLRINNEIYEVQTRDLLVKDGVVHLVDKVKLPFSVSQKDMIIAGGRKEFLELLDKFEMLDMLDSGYPVVVPSLTGSDVNTKDSSFAERHIIDPEKRNFVISGSRLSVDSSPWISIQDYGYSELGNVYFVQNAIPTKRQNRWRITFISISGLLLSVGICVLCYKIYFKFFRNRFMNQGEREPLLAPADSDTMAGRRNSSSLSV

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
29	Phosphorylation	KNEYEDKSTSIIDLL CCCCCCCCCCHHHHH		25720772
30	Phosphorylation	NEYEDKSTSIIDLLS CCCCCCCCCHHHHHC		25720772
89	N-linked_Glycosylation	NLLYYIVNTTELDRS CCEEEEEECCHHCHH		-
404	N-linked_Glycosylation	IQSENIGNVSLYVLD EEECCCCEEEEEEEC		-
501	N-linked_Glycosylation	DEAWASGNYTTLSNK CCHHHCCCEEECCCC		-
723	Phosphorylation	TMAGRRNSSSLSV-- CCCCCCCCCCCCC--		25720772
724	Phosphorylation	MAGRRNSSSLSV--- CCCCCCCCCCCC---		25720772
725	Phosphorylation	AGRRNSSSLSV---- CCCCCCCCCCC----		25720772
727	Phosphorylation	RRNSSSLSV------ CCCCCCCCC------		25720772

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of FSC1_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of FSC1_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of FSC1_SCHPO !!

Protein-Protein Interaction

Oops, there are no PPI records of FSC1_SCHPO !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.