YET4_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: YET4_SCHPO
• UniProt AC: O14273
• Protein Name: Meiotically up-regulated protein C8C9.04
• Gene Name: SPAC8C9.04
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 647
• Protein Description: Has a role in meiosis and sporulation..
• Protein Sequence: MTTNPDIVKQTKNEIHQVTSRVQEKLDSKSTNAVEQNNNSSQASVTKDNKKKAAKRAKKKAAKKKKQSAAASASSTPVEEAQHAQEEQQEQTILQEPGFTQTIVEKDADQVDEPLEPIASSALGTVEPPTDNKPSASTSTAVPTTEARNTSITEPANSPSSSSSSASTKSTATTQSADYVVAEHFAPQRNDEQLGNSPASITSKPATTSAAQPSSKVEENMAKATSQPITTAEKEIPELKPIEPEAIMISKEINTTHDQAAATTTAAVASASTTATAESHAVADGIMNDNVLESIGENVQQETVFEDASDIPHADVIPHTTTVTVEEESPIALGQGGVTHEATTSARASASGIPGAFEEVQQTVQEDLPHPTAETVEIARFAEQPVRAQQPEQYESSVVQEATETVTDVGKGVSSTVKNEVNVPSTIPTESENPVAVGGTTAEHPVQEAVTAPTETAHDFSKETTTASKRVSKHDKASAEKHKVARKPSSTGQEPTTPSTPAKSAQSSKHARRPSKQASAPSSPGTTSAAVPGGKKSAIEAAAPIPTSADTVESKHAAGSGSATTIPSPGSATTKPTPGSATTKPTPVSATEEHAAGTTKPAPAAGATATAENETADGKAQTATDGEAAPKKSWFKRMKKSFGKLFH

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
19	Phosphorylation	KNEIHQVTSRVQEKL HHHHHHHHHHHHHHH	12.30	25720772
20	Phosphorylation	NEIHQVTSRVQEKLD HHHHHHHHHHHHHHC	31.43	21712547
28	Phosphorylation	RVQEKLDSKSTNAVE HHHHHHCCCCCCHHH	38.65	25720772
30	Phosphorylation	QEKLDSKSTNAVEQN HHHHCCCCCCHHHHC	30.74	29996109
31	Phosphorylation	EKLDSKSTNAVEQNN HHHCCCCCCHHHHCC	30.82	29996109
40	Phosphorylation	AVEQNNNSSQASVTK HHHHCCCCCCCCCCH	26.42	25720772
41	Phosphorylation	VEQNNNSSQASVTKD HHHCCCCCCCCCCHH	31.71	24763107
44	Phosphorylation	NNNSSQASVTKDNKK CCCCCCCCCCHHHHH	23.76	24763107
46	Phosphorylation	NSSQASVTKDNKKKA CCCCCCCCHHHHHHH	30.13	29996109
150	Phosphorylation	PTTEARNTSITEPAN CCCCCCCCCCCCCCC	18.89	25720772
151	Phosphorylation	TTEARNTSITEPANS CCCCCCCCCCCCCCC	30.94	25720772
158	Phosphorylation	SITEPANSPSSSSSS CCCCCCCCCCCCCCC	28.41	28889911
162	Phosphorylation	PANSPSSSSSSASTK CCCCCCCCCCCCCCC	38.28	28889911
163	Phosphorylation	ANSPSSSSSSASTKS CCCCCCCCCCCCCCC	30.20	29996109
164	Phosphorylation	NSPSSSSSSASTKST CCCCCCCCCCCCCCC	31.69	29996109
165	Phosphorylation	SPSSSSSSASTKSTA CCCCCCCCCCCCCCC	28.34	28889911
167	Phosphorylation	SSSSSSASTKSTATT CCCCCCCCCCCCCCC	38.01	29996109
168	Phosphorylation	SSSSSASTKSTATTQ CCCCCCCCCCCCCCC	28.82	28889911
170	Phosphorylation	SSSASTKSTATTQSA CCCCCCCCCCCCCCC	24.30	25720772
171	Phosphorylation	SSASTKSTATTQSAD CCCCCCCCCCCCCCC	29.58	28889911
173	Phosphorylation	ASTKSTATTQSADYV CCCCCCCCCCCCCEE	26.00	28889911
174	Phosphorylation	STKSTATTQSADYVV CCCCCCCCCCCCEEE	20.33	29996109
176	Phosphorylation	KSTATTQSADYVVAE CCCCCCCCCCEEEEE	22.48	28889911
179	Phosphorylation	ATTQSADYVVAEHFA CCCCCCCEEEEECCC	9.13	28889911
197	Phosphorylation	NDEQLGNSPASITSK CHHHHCCCCCCCCCC	21.75	28889911
200	Phosphorylation	QLGNSPASITSKPAT HHCCCCCCCCCCCCC	29.77	28889911
202	Phosphorylation	GNSPASITSKPATTS CCCCCCCCCCCCCCC	28.36	29996109
203	Phosphorylation	NSPASITSKPATTSA CCCCCCCCCCCCCCC	34.66	28889911
207	Phosphorylation	SITSKPATTSAAQPS CCCCCCCCCCCCCCC	29.79	25720772
208	Phosphorylation	ITSKPATTSAAQPSS CCCCCCCCCCCCCCH	20.62	25720772
226	Phosphorylation	ENMAKATSQPITTAE HHHHHHHCCCCCHHH	38.53	25720772
349	Phosphorylation	ATTSARASASGIPGA ECCHHHHHHHCCCCH	19.88	29996109
351	Phosphorylation	TSARASASGIPGAFE CHHHHHHHCCCCHHH	34.46	29996109
363	Phosphorylation	AFEEVQQTVQEDLPH HHHHHHHHHHHCCCC	13.68	29996109
394	Phosphorylation	RAQQPEQYESSVVQE CCCCHHHHHHHHHHH	19.00	29996109
396	Phosphorylation	QQPEQYESSVVQEAT CCHHHHHHHHHHHHH	24.41	28889911
397	Phosphorylation	QPEQYESSVVQEATE CHHHHHHHHHHHHHH	17.86	25720772
426	Phosphorylation	NEVNVPSTIPTESEN CCCCCCCCCCCCCCC	25.55	27738172
478	Phosphorylation	VSKHDKASAEKHKVA HCHHHHHHHHHHCCC	42.58	21712547
489	Phosphorylation	HKVARKPSSTGQEPT HCCCCCCCCCCCCCC	43.50	28889911
490	Phosphorylation	KVARKPSSTGQEPTT CCCCCCCCCCCCCCC	45.12	28889911
491	Phosphorylation	VARKPSSTGQEPTTP CCCCCCCCCCCCCCC	47.42	28889911
496	Phosphorylation	SSTGQEPTTPSTPAK CCCCCCCCCCCCCCH	51.06	29996109
497	Phosphorylation	STGQEPTTPSTPAKS CCCCCCCCCCCCCHH	26.42	25720772
499	Phosphorylation	GQEPTTPSTPAKSAQ CCCCCCCCCCCHHHC	44.95	24763107
500	Phosphorylation	QEPTTPSTPAKSAQS CCCCCCCCCCHHHCC	28.59	21712547
504	Phosphorylation	TPSTPAKSAQSSKHA CCCCCCHHHCCCCCC	33.38	25720772
507	Phosphorylation	TPAKSAQSSKHARRP CCCHHHCCCCCCCCC	40.86	25720772
508	Phosphorylation	PAKSAQSSKHARRPS CCHHHCCCCCCCCCC	19.17	25720772
515	Phosphorylation	SKHARRPSKQASAPS CCCCCCCCCCCCCCC	35.27	28889911
519	Phosphorylation	RRPSKQASAPSSPGT CCCCCCCCCCCCCCC	37.91	28889911
522	Phosphorylation	SKQASAPSSPGTTSA CCCCCCCCCCCCCCC	49.21	24763107
523	Phosphorylation	KQASAPSSPGTTSAA CCCCCCCCCCCCCCC	26.70	28889911
526	Phosphorylation	SAPSSPGTTSAAVPG CCCCCCCCCCCCCCC	22.44	25720772
527	Phosphorylation	APSSPGTTSAAVPGG CCCCCCCCCCCCCCC	23.45	21712547
528	Phosphorylation	PSSPGTTSAAVPGGK CCCCCCCCCCCCCCC	17.67	24763107
537	Phosphorylation	AVPGGKKSAIEAAAP CCCCCCHHHHHHCCC	37.65	24763107
547	Phosphorylation	EAAAPIPTSADTVES HHCCCCCCCCHHHHC	36.95	21712547
548	Phosphorylation	AAAPIPTSADTVESK HCCCCCCCCHHHHCC	20.84	21712547
551	Phosphorylation	PIPTSADTVESKHAA CCCCCCHHHHCCCCC	26.37	21712547
554	Phosphorylation	TSADTVESKHAAGSG CCCHHHHCCCCCCCC	25.96	25720772
560	Phosphorylation	ESKHAAGSGSATTIP HCCCCCCCCCCCCCC	25.50	24763107
562	Phosphorylation	KHAAGSGSATTIPSP CCCCCCCCCCCCCCC	24.92	24763107
564	Phosphorylation	AAGSGSATTIPSPGS CCCCCCCCCCCCCCC	27.27	24763107
565	Phosphorylation	AGSGSATTIPSPGSA CCCCCCCCCCCCCCC	30.52	21712547
568	Phosphorylation	GSATTIPSPGSATTK CCCCCCCCCCCCCCC	37.73	24763107
571	Phosphorylation	TTIPSPGSATTKPTP CCCCCCCCCCCCCCC	26.31	21712547
573	Phosphorylation	IPSPGSATTKPTPGS CCCCCCCCCCCCCCC	36.73	21712547
580	Phosphorylation	TTKPTPGSATTKPTP CCCCCCCCCCCCCCC	24.52	21712547
583	Phosphorylation	PTPGSATTKPTPVSA CCCCCCCCCCCCCCC	34.44	21712547
586	Phosphorylation	GSATTKPTPVSATEE CCCCCCCCCCCCCCH	37.57	21712547
615	Phosphorylation	TATAENETADGKAQT CEEEECCCCCCCCCC	41.45	27738172
622	Phosphorylation	TADGKAQTATDGEAA CCCCCCCCCCCCCCC	36.06	21712547
624	Phosphorylation	DGKAQTATDGEAAPK CCCCCCCCCCCCCCC	48.18	21712547

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of YET4_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of YET4_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of YET4_SCHPO !!

Protein-Protein Interaction

Oops, there are no PPI records of YET4_SCHPO !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Phosphoproteome analysis of fission yeast.";
Wilson-Grady J.T., Villen J., Gygi S.P.;
J. Proteome Res. 7:1088-1097(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-162; SER-165; THR-168;SER-197; SER-200; SER-396; SER-489; SER-490; THR-491; SER-515; SER-519AND SER-523, AND MASS SPECTROMETRY.
PubMed: 18257517