2AD2_SCHPO - dbPTM
2AD2_SCHPO - PTM Information in dbPTM
Basic Information of Protein
UniProt ID 2AD2_SCHPO
UniProt AC P78759
Protein Name Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta 2 isoform
Gene Name par2
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length 627
Subcellular Localization Cytoplasm. Nucleus.
Protein Description The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. Has a role in cell shape control and septum formation..
Protein Sequence MKGLRSKFVKALSLKDEQGSHKNGHSKSHYISKNGSYVETDDVKHTDTHHSSKHELKKLKSHFLKDTLKHKRNHHANSNNEKHENSDKKIHTTVLASGHEDSDYSTFLPVIETSKVKDANHFPPNYPEPKNDSVSSNIDEFPNDSISSASFLSVPQSTPPYLVSQPTPLNKFLAGAENVDIPHSLRPVPRREHSSQFQVSEKRTLVRLPSFDDVHTSEREELFIKKLEQCNIIFDFNDPSSDLASKEIKREALLQMIDYVSENRGISSASLFPYVVNTFSLNVFRPISPALNDYSSDMFALDDEPFLEPAWPHLEEVYLLFIKFLESPDFRASKAKSLVDRRFFNRLLALFDTEDPRERELLKTTLHRIYGKFLNLRSYIRKSMNNVFLQFIYEREKFHGIAELLEILGSIINGFAVPLKEEHKIFLSKVLIPLHQTKSVFLYHPQLTYCIVQFIDKDPSLTKAVLTGILKYWPRINSFKELLFLNEIEDIFEVLEPSEFVNIMSPLFQQLARSISSMHFQVAERALCLWSNEYFTSLVSQNVVTLLPIIYPSLYKTANEHWNSTIQAIACNVLQIFVDMDADFFNGLVEDYKQAIIKQEEVMIIRKQQWCQIEALAAENKPTDYLR
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
194PhosphorylationPVPRREHSSQFQVSE
CCCCCCCCCCCCCCC
22.5329996109
195PhosphorylationVPRREHSSQFQVSEK
CCCCCCCCCCCCCCC
36.6029996109
200PhosphorylationHSSQFQVSEKRTLVR
CCCCCCCCCCEEEEE
26.9829996109

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of 2AD2_SCHPO !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of 2AD2_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of 2AD2_SCHPO !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
ASH2_SCHPOash2genetic
18818364
2AD1_SCHPOpar1genetic
18818364
SKI2_SCHPOSPCC550.03cgenetic
18818364
CCR4_SCHPOccr4genetic
18818364
ARP6_SCHPOarp6genetic
18818364
ASL1_SCHPOasl1genetic
22681890
TCO89_SCHPOtco89genetic
22681890
ILVB_SCHPOilv1genetic
22681890
YGD6_SCHPOadh8genetic
22681890
YAY3_SCHPOSPAC4H3.03cgenetic
22681890
DPH3_SCHPOdph3genetic
22681890
YI81_SCHPOSPAPJ695.01cgenetic
22681890
AP2S_SCHPOaps2genetic
22681890
G3P2_SCHPOgpd3genetic
22681890
SEC7B_SCHPOsec72genetic
22681890
ALY1_SCHPOSPBC839.02genetic
22681890
YOG5_SCHPOSPBC15D4.05genetic
22681890
SUT1_SCHPOsut1genetic
22681890
ISN1_SCHPOSPBC30D10.03cgenetic
22681890
YE1A_SCHPOSPAC1B3.10cgenetic
22681890
CAT1_SCHPOcat1genetic
22681890
CG121_SCHPOcgi121genetic
22681890
YN84_SCHPOSPBP35G2.04cgenetic
22681890
GIT3_SCHPOgit3genetic
22681890
POM1_SCHPOpom1genetic
22681890
YI31_SCHPOSPAC1399.01cgenetic
22681890
PHD1_SCHPOhos2genetic
22681890
YGB8_SCHPOSPBC25B2.08genetic
22681890
SUMT_SCHPOSPCC1739.06cgenetic
22681890
HIS2_SCHPOhis7genetic
22681890
NTO1_SCHPOnto1genetic
22681890
LYS4_SCHPOlys2genetic
22681890
YB22_SCHPOSPBC31F10.02genetic
22681890
PEX6_SCHPOpex6genetic
22681890
HMT1_SCHPOhmt1genetic
22681890
PPK38_SCHPOppk38genetic
22681890
SHR3_SCHPOpsh3genetic
22681890
YORS_SCHPOstc1genetic
22681890
SVP26_SCHPOSPCC1795.10cgenetic
22681890
ALAT_SCHPOSPBC582.08genetic
22681890
YB0A_SCHPOSPBC25H2.10cgenetic
22681890
SPF31_SCHPOspf31genetic
22681890
ADRM1_SCHPOrpn1302genetic
22681890
PDE1_SCHPOcgs2genetic
22681890
IMA2_SCHPOimp1genetic
22681890
RHO3_SCHPOrho3genetic
22681890
YBD1_SCHPOSPBC16C6.01cgenetic
22681890
BGLS_SCHPOSPBC1683.04genetic
22681890
YOX1_SCHPOyox1genetic
22681890
NOP12_SCHPOnop12genetic
22681890
PSK1_SCHPOpsk1genetic
22681890

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of 2AD2_SCHPO

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Related Literatures of Post-Translational Modification

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