| UniProt ID | EST1_SCHPO | |
|---|---|---|
| UniProt AC | O74804 | |
| Protein Name | Telomere elongation protein est1 | |
| Gene Name | est1 | |
| Organism | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast). | |
| Sequence Length | 490 | |
| Subcellular Localization | Nucleus . Chromosome, telomere . | |
| Protein Description | Directly involved in telomere replication. Associates with telomerase and during its interaction with trt1, telomerase activity is promoted.. | |
| Protein Sequence | MSQQLSSNEICEEQGKLVKALCEAAQGGFKHDLYEKIIAIEIEVEKKLLNRLKSIQTNTFERPDIIWSCCHYKIIQHFRSRFREIHPRHVVEKKKTKKVFFKFLKTCAIFYQTCISELISKFQLDSYRPFFCKWTSSATVSSTISNDEMSSIPEASYSRNHMEALECVYNCFIYLGDMARYSSTCLKKRGAYDRALGFYDLAHRTLPGNGMHRNQIAVVWASDECIVESIYWFSSALCSEDPPKSALLNLLKQLIAFYRRCFAVHFEFVSPMMILLFIISDCCIHSLKEIQPFKCPSIMVKDLENSLLQSNIRNVGYEKKNLYYISSAFSNLLHCRYFNCNDRLRSFYYRFSSWLFHQTLACAKEVESERAPTSYLTSCLPSIKVILARVLESSPAFGFIERNELEQLSYHFRICEKFFKESSENKMLNLFEDYNEFGLCKSFICLFKRLNEDIIGPKLNINPPDYTTHPFSESIKRFYQISKILNLLLS | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|
|---|---|---|---|---|---|---|
Oops, there are no PTM records of EST1_SCHPO !! | ||||||
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of EST1_SCHPO !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of EST1_SCHPO !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of EST1_SCHPO !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| TERT_SCHPO | trt1 | physical | 12676088 | |
| YB33_SCHPO | ebs1 | genetic | 18818364 | |
| RAD14_SCHPO | rhp14 | genetic | 18818364 | |
| TAS3_SCHPO | tas3 | genetic | 18818364 | |
| YME2_SCHPO | SPBC83.05 | genetic | 18818364 | |
| AIR1_SCHPO | air1 | genetic | 18818364 | |
| RPA12_SCHPO | rpa12 | genetic | 18818364 | |
| MU154_SCHPO | mug154 | genetic | 18818364 | |
| CCQ1_SCHPO | ccq1 | physical | 22101932 | |
| DCTD_SCHPO | dcd1 | genetic | 22681890 | |
| YIDH_SCHPO | SPAC227.17c | genetic | 22681890 | |
| HOP1_SCHPO | hop1 | genetic | 22681890 | |
| TERT_SCHPO | trt1 | physical | 25131669 | |
| CCQ1_SCHPO | ccq1 | physical | 25131669 | |
| SWI1_SCHPO | swi1 | genetic | 26990647 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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