TERT_SCHPO - dbPTM
TERT_SCHPO - PTM Information in dbPTM
Basic Information of Protein
UniProt ID TERT_SCHPO
UniProt AC O13339
Protein Name Telomerase reverse transcriptase {ECO:0000312|PomBase:SPBC29A3.14c}
Gene Name trt1 {ECO:0000312|PomBase:SPBC29A3.14c}
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length 988
Subcellular Localization Nucleus. Chromosome, telomere.
Protein Description Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme..
Protein Sequence MTEHHTPKSRILRFLENQYVYLCTLNDYVQLVLRGSPASSYSNICERLRSDVQTSFSIFLHSTVVGFDSKPDEGVQFSSPKCSQSELIANVVKQMFDESFERRRNLLMKGFSMNHEDFRAMHVNGVQNDLVSTFPNYLISILESKNWQLLLEIIGSDAMHYLLSKGSIFEALPNDNYLQISGIPLFKNNVFEETVSKKRKRTIETSITQNKSARKEVSWNSISISRFSIFYRSSYKKFKQDLYFNLHSICDRNTVHMWLQWIFPRQFGLINAFQVKQLHKVIPLVSQSTVVPKRLLKVYPLIEQTAKRLHRISLSKVYNHYCPYIDTHDDEKILSYSLKPNQVFAFLRSILVRVFPKLIWGNQRIFEIILKDLETFLKLSRYESFSLHYLMSNIKISEIEWLVLGKRSNAKMCLSDFEKRKQIFAEFIYWLYNSFIIPILQSFFYITESSDLRNRTVYFRKDIWKLLCRPFITSMKMEAFEKINENNVRMDTQKTTLPPAVIRLLPKKNTFRLITNLRKRFLIKMGSNKKMLVSTNQTLRPVASILKHLINEESSGIPFNLEVYMKLLTFKKDLLKHRMFGRKKYFVRIDIKSCYDRIKQDLMFRIVKKKLKDPEFVIRKYATIHATSDRATKNFVSEAFSYFDMVPFEKVVQLLSMKTSDTLFVDFVDYWTKSSSEIFKMLKEHLSGHIVKIGNSQYLQKVGIPQGSILSSFLCHFYMEDLIDEYLSFTKKKGSVLLRVVDDFLFITVNKKDAKKFLNLSLRGFEKHNFSTSLEKTVINFENSNGIINNTFFNESKKRMPFFGFSVNMRSLDTLLACPKIDEALFNSTSVELTKHMGKSFFYKILRSSLASFAQVFIDITHNSKFNSCCNIYRLGYSMCMRAQAYLKRMKDIFIPQRMFITDLLNVIGRKIWKKLAEILGYTSRRFLSSAEVKWLFCLGMRDGLKPSFKYHPCFEQLIYQFQSLTDLIKPLRPVLRQVLFLHRRIAD
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster

Oops, there are no PTM records of TERT_SCHPO !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of TERT_SCHPO !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of TERT_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of TERT_SCHPO !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
EST1_SCHPOest1physical
12676088
TAZ1_SCHPOtaz1genetic
12676088
TAZ1_SCHPOtaz1genetic
20040595
CCQ1_SCHPOccq1genetic
20040595
ATM_SCHPOtel1genetic
20505337
PVG2_SCHPOpvg2genetic
22681890
NSE6_SCHPOnse6genetic
22681890
IMP2L_SCHPOSPBC336.13cgenetic
22681890
REB1_SCHPOreb1genetic
22681890
VTS1_SCHPOSPBC13E7.03cgenetic
22681890
RAF2_SCHPOraf2genetic
22681890
ALY1_SCHPOSPBC839.02genetic
22681890
PROB_SCHPOSPAC17H9.13cgenetic
22681890
ITR1_SCHPOitr1genetic
22681890
NUP60_SCHPOnup60genetic
22681890
CSK2C_SCHPOckb2genetic
22681890
MGR2_SCHPOmgr2genetic
22681890
ARGJ_SCHPOSPBC1271.14genetic
22681890
CIP1_SCHPOcip1genetic
22681890
CCQ1_SCHPOccq1genetic
22681890
UAF30_SCHPOspp27genetic
22681890
MBO1_SCHPOmto1genetic
22681890
YE08_SCHPOSPAC17H9.08genetic
22681890
ZIP1_SCHPOzip1genetic
22681890
DCTD_SCHPOdcd1genetic
22681890
MEU10_SCHPOmeu10genetic
22681890
MU109_SCHPOmug109genetic
22681890
PDR1_SCHPOpdr1genetic
22681890
NAGS_SCHPOarg6genetic
22681890
TEA2_SCHPOtea2genetic
22681890
GLYD_SCHPOSPAC24C9.12cgenetic
22681890
HOSM_SCHPOlys4genetic
22681890
YET4_SCHPOSPAC8C9.04genetic
22681890
MFM2_SCHPOmfm2genetic
22681890
YKT4_SCHPOSPAPB1E7.04cgenetic
22681890
NUP61_SCHPOnup61genetic
22681890
PPZ_SCHPOpzh1genetic
22681890
YGVA_SCHPOdef1genetic
22681890
RAF1_SCHPOraf1genetic
22681890
RM01_SCHPOSPAC1610.02cgenetic
22681890
RSSA1_SCHPOrps001genetic
22681890
ROK1_SCHPOrok1genetic
22681890
RL16B_SCHPOrpl1601genetic
22681890
PFD6_SCHPOSPAC3A11.13genetic
22681890
ERD11_SCHPOerd1genetic
22681890
SAT1_SCHPOsat1genetic
22681890
YA99_SCHPOSPAC13G6.09genetic
22681890
H2AZ_SCHPOpht1genetic
22681890
IMA2_SCHPOimp1genetic
22681890
MCL1_SCHPOmcl1genetic
22681890
MUG51_SCHPOmug51genetic
22681890
FYV10_SCHPOSPBC106.13genetic
22681890
YETC_SCHPOSPAC8C9.12cgenetic
22681890
YE85_SCHPOaip1genetic
22681890
RS12A_SCHPOrps1201genetic
22681890
YA9D_SCHPOSPAC13G6.13genetic
22681890
RAD16_SCHPOrad16genetic
23335786
RAD32_SCHPOmre11genetic
23335786
RAD50_SCHPOrad50genetic
23335786
NBS1_SCHPOnbs1genetic
23335786
COM1_SCHPOctp1genetic
23335786
SWI1_SCHPOswi1genetic
26990647

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of TERT_SCHPO

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Related Literatures of Post-Translational Modification

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