| UniProt ID | RAD16_SCHPO | |
|---|---|---|
| UniProt AC | P36617 | |
| Protein Name | DNA repair protein rad16 | |
| Gene Name | rad16 | |
| Organism | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast). | |
| Sequence Length | 877 | |
| Subcellular Localization | Nucleus . Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body . | |
| Protein Description | Endonuclease that specifically degrades single-stranded DNA and which is involved in nucleotide excision repair of DNA damaged with UV light, bulky adducts, or cross-linking agents. Required for double strand break-induced interchromosomal gene conversion.. | |
| Protein Sequence | METKVHLPLAYQQQVFNELIEEDGLCVIAPGLSLLQIAANVLSYFAVPGSLLLLVGANVDDIELIQHEMESHLEKKLITVNTETMSVDKREKSYLEGGIFAITSRILVMDLLTKIIPTEKITGIVLLHADRVVSTGTVAFIMRLYRETNKTGFIKAFSDDPEQFLMGINALSHCLRCLFLRHVFIYPRFHVVVAESLEKSPANVVELNVNLSDSQKTIQSCLLTCIESTMRELRRLNSAYLDMEDWNIESALHRSFDVIVRRQLDSVWHRVSPKTKQLVGDLSTLKFLLSALVCYDCVSFLKLLDTLVLSVNVSSYPSNAQPSPWLMLDAANKMIRVARDRVYKESEGPNMDAIPILEEQPKWSVLQDVLNEVCHETMLADTDAETSNNSIMIMCADERTCLQLRDYLSTVTYDNKDSLKNMNSKLVDYFQWREQYRKMSKSIKKPEPSKEREASNTTSRKGVPPSKRRRVRGGNNATSRTTSDNTDANDSFSRDLRLEKILLSHLSKRYEPEVGNDAFEVIDDFNSIYIYSYNGERDELVLNNLRPRYVIMFDSDPNFIRRVEVYKATYPKRSLRVYFMYYGGSIEEQKYLFSVRREKDSFSRLIKERSNMAIVLTADSERFESQESKFLRNVNTRIAGGGQLSITNEKPRVIVDLREFRSSLPSILHGNNFSVIPCQLLVGDYILSPKICVERKSIRDLIQSLSNGRLYSQCEAMTEYYEIPVLLIEFEQHQSFTSPPFSDLSSEIGKNDVQSKLVLLTLSFPNLRIVWSSSAYVTSIIFQDLKAMEQEPDPASAASIGLEAGQDSTNTYNQAPLDLLMGLPYITMKNYRNVFYGGVKDIQEASETSERKWSELIGPEAGRRLYSFFRKQLKDYE | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 71 | Phosphorylation | LIQHEMESHLEKKLI HHHHHHHHHHHHHEE | 31.87 | - |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
| 71 | S | Phosphorylation | Kinase | CK2 | - | Uniprot |
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of RAD16_SCHPO !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of RAD16_SCHPO !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| UVE1_SCHPO | uve1 | genetic | 22665798 | |
| SWI5_SCHPO | swi5 | genetic | 2598273 | |
| MAG2_SCHPO | mag2 | genetic | 18270439 | |
| MAG1_SCHPO | mag1 | genetic | 18270439 | |
| CDC24_SCHPO | cdc24 | physical | 25203555 | |
| SWI10_SCHPO | swi10 | physical | 25203555 | |
| YCD2_SCHPO | pxd1 | physical | 25203555 | |
| SPO11_SCHPO | rec12 | genetic | 25293972 | |
| CHK1_SCHPO | chk1 | genetic | 25293972 | |
| MUS81_SCHPO | mus81 | genetic | 25293972 | |
| RAD3_SCHPO | rad3 | genetic | 25293972 | |
| HUS2_SCHPO | rqh1 | genetic | 25293972 | |
| PCNA_SCHPO | pcn1 | genetic | 25293972 | |
| RAD18_SCHPO | rhp18 | genetic | 25293972 | |
| FEN1_SCHPO | rad2 | genetic | 25293972 | |
| MMS2_SCHPO | mms2 | genetic | 25293972 | |
| UBC13_SCHPO | ubc13 | genetic | 25293972 | |
| POLK_SCHPO | kpa1 | genetic | 25293972 | |
| APN2_SCHPO | apn2 | genetic | 25293972 | |
| NTH_SCHPO | nth1 | genetic | 25293972 | |
| ESO1_SCHPO | eso1 | genetic | 25293972 | |
| YHAG_SCHPO | saw1 | physical | 25777942 | |
| YCD2_SCHPO | pxd1 | physical | 25777942 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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