dbPTM

POLK_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	POLK_SCHPO
UniProt AC	O74944
Protein Name	DNA polymerase kappa
Gene Name	mug40
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	547
Subcellular Localization	Cytoplasm. Nucleus. Associates with chromatin.
Protein Description	DNA polymerase specifically involved in DNA repair. Plays an important role in translesion synthesis, where the normal high-fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Has a role in meiosis..
Protein Sequence	MENAKDFIGETIKENGLLTIEDDGSSSSDEEATLKRRLAGPSVLKSGQENVNQKKINEIIYEASKGSKFFEAEQKRDRELRLRIEKVQVEVEKYQSKLRFDKAFQREWTIRQESVDTTVEDFRAKRDLTQIIVHVDCDAFYASIEELKNPKLKSLPMAVGKSVLCTANYVARKFGVRSAMPEFIARKICPDLVVIPLNLSEYAIKSKEIQNVLAQYDSNLCPASIDEFYMNLTSHLRLQELAFTVENITMVVEKIRKQVHEETGVTVSCGIAANKLLAKIASNKRKPNNQFFIPFDEIGISKFMNDLPVREVSGIGRVLEQQLLGLEIKTCGDIQRNLVILSYIFLPKSFQNLLRCSYGFGTTILDEYGESKRKTIGSEATFSSNLSSPSIIEYKLRLLVQNVSENLQKRGLVTNSIAIKYKTSEFQVHTKQKSIGQFIHSESDLLKPALQLLRQSYPMTIRLLGVRATKLVSKSRCLAMQLKFQSQNTVPCPVCQKNIENELGILNQHVDLCLNVETVKSLINTDHTANPTIKKRKSNTLDTYFLE

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
Oops, there are no PTM records of POLK_SCHPO !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of POLK_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of POLK_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of POLK_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
RAD1_SCHPO	rad1	physical	12514100
HUS1_SCHPO	hus1	physical	12514100
DPOZ_SCHPO	rev3	genetic	20453833
REV1_SCHPO	rev1	genetic	20453833
POLK_SCHPO	kpa1	physical	26771498

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of POLK_SCHPO

Related Literatures of Post-Translational Modification