dbPTM

POZ1_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	POZ1_SCHPO
UniProt AC	O13852
Protein Name	Protection of telomeres protein poz1
Gene Name	poz1
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	249
Subcellular Localization	Cytoplasm . Nucleus . Chromosome, telomere .
Protein Description	Telomeric DNA-binding protein that negatively regulates telomerase and telomere length..
Protein Sequence	MNEKIRSQSVLNTLETFFIKENHYDMQREESSIVNACLRYLGYSKSMCHEKMPIFMDIAFIEYCFNLSLDPSSFQNLPITQTQPDSQQILWEYSLISNALERLENIELERQNCMREDGLVKYTNELLLNKETLNNEALKLYSCAKAGICRWMAFHFLEQEPIDHINFTKFLQDWGSHNEKEMEALQRLSKHKIRKRLIYVSQHKKKMPWSKFNSVLSRYIQCTKLQLEVFCDYDFKQREIVKMLTSNIN

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
214	Phosphorylation	MPWSKFNSVLSRYIQ CCHHHHHHHHHHHHC	27.80	24763107
217	Phosphorylation	SKFNSVLSRYIQCTK HHHHHHHHHHHCCCC	22.38	24763107

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of POZ1_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of POZ1_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of POZ1_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
RAD3_SCHPO	rad3	genetic	22354040
RFA1_SCHPO	ssb1	genetic	22354040
RAP1_SCHPO	rap1	physical	22959349
MPH1L_SCHPO	mph1	genetic	22681890
CTBL1_SCHPO	SPAC1952.06c	genetic	22681890
CCQ1_SCHPO	ccq1	genetic	22681890
SPP1_SCHPO	spf1	genetic	22681890
JHD1_SCHPO	epe1	genetic	22681890
ASK1_SCHPO	ask1	genetic	22681890
FFT3_SCHPO	fft3	genetic	22681890
YNF3_SCHPO	SPBC17A3.03c	genetic	22681890
MCL1_SCHPO	mcl1	genetic	22681890
TAZ1_SCHPO	taz1	genetic	24244195
TPZ1_SCHPO	tpz1	physical	24711392
CCQ1_SCHPO	ccq1	physical	24711392
TPZ1_SCHPO	tpz1	physical	26365187
TPZ1_SCHPO	tpz1	physical	26771498
RAP1_SCHPO	rap1	physical	26988418
TPZ1_SCHPO	tpz1	physical	26988418
POT1_SCHPO	pot1	physical	26988418
CCQ1_SCHPO	ccq1	physical	26988418
TAZ1_SCHPO	taz1	physical	26988418
CLR4_SCHPO	clr4	physical	26988418
CUL4_SCHPO	pcu4	physical	26988418
RIK1_SCHPO	rik1	physical	26988418
RAF1_SCHPO	raf1	physical	26988418
RAF2_SCHPO	raf2	physical	26988418
CLR3_SCHPO	clr3	physical	26988418
MST2_SCHPO	mst2	genetic	26988418
NTO1_SCHPO	nto1	genetic	26988418
PTF2_SCHPO	ptf2	genetic	26988418
JHD1_SCHPO	epe1	genetic	26988418
SWI6_SCHPO	swi6	genetic	26988418
SWI1_SCHPO	swi1	genetic	26990647

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of POZ1_SCHPO

Related Literatures of Post-Translational Modification