SET11_SCHPO - dbPTM
SET11_SCHPO - PTM Information in dbPTM
Basic Information of Protein
UniProt ID SET11_SCHPO
UniProt AC O74405
Protein Name Ribosomal lysine N-methyltransferase set11
Gene Name set11
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length 381
Subcellular Localization Cytoplasm. Nucleus, nucleolus.
Protein Description S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that trimethylates 60S ribosomal protein L12 (rpl1201 and rpl1202) at 'Lys-4' and may dimethylate L12 also at 'Lys-40' and 'Lys-41'. Overexpression causes a severe growth defect. Has a role in meiosis..
Protein Sequence MSNKQNIESEVSWVKSKGAFVHPSLEFSVIPDAGSCVLANNDINENTVLLKLPPNILINKRTCSRYSFRDKLTSFQFLSWLISEDVHSNLEISPYYTKALPQGFSFHPVTLTSDHPLWSILPDEVRNSLLERKNVMAFDYEQVKKFVSVDQPTFQWGWLCVNTRCLYYDTGSKNTEDHLTLAPIFEYFNHSPEAQTALINTRGTITIKSTRRIDKGEQIFLCYGPHGNDKLFTEYGFCLSNNPNISIQLDRFIEFDKWQQSFLQDHGYWNDYTCSLHGASFRTLVGVRTLLVSPSEKLNDASYDQTRRVLQYINGFSDGSRDRQDVEDYLKKVLQELLCEAEECKEKVKGISDGSYVFICAEQLWKDRIMCCQYLMEHSFE
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster

Oops, there are no PTM records of SET11_SCHPO !!
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of SET11_SCHPO !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of SET11_SCHPO !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of SET11_SCHPO !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
KLP6_SCHPOklp6genetic
18931302
NU132_SCHPOnup132genetic
22681890
BUB3_SCHPObub3genetic
22681890
6PGL_SCHPOSPCC16C4.10genetic
22681890
RAF2_SCHPOraf2genetic
22681890
ARP6_SCHPOarp6genetic
22681890
SWD3_SCHPOswd3genetic
22681890
YAC5_SCHPOcph1genetic
22681890
YK82_SCHPObdf2genetic
22681890
RPA12_SCHPOrpa12genetic
22681890
CLR4_SCHPOclr4genetic
22681890
DAD1_SCHPOdad1genetic
22681890
ASH2_SCHPOash2genetic
22681890
YO48_SCHPOSPBC36B7.08cgenetic
22681890
MAD2_SCHPOmad2genetic
22681890
RAF1_SCHPOraf1genetic
22681890
ATP11_SCHPOatp11genetic
22681890
MU172_SCHPOmsd1genetic
22681890
RL27A_SCHPOrpl2701genetic
22681890
SEC14_SCHPOspo20genetic
22681890
TOM70_SCHPOtom70genetic
22681890
FFT3_SCHPOfft3genetic
22681890
KLP6_SCHPOklp6genetic
22681890
MCL1_SCHPOmcl1genetic
22681890
MAD1_SCHPOmad1genetic
22681890
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of SET11_SCHPO

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Related Literatures of Post-Translational Modification

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