MDE2_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: MDE2_SCHPO
• UniProt AC: P87309
• Protein Name: Mei4-dependent protein 2
• Gene Name: mde2 {ECO:0000303|PubMed:10747048}
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 278
• Protein Description: Required for the formation of meiotic double-strand breaks and for the segregation of homologous centromeres during meiosis I. [PubMed: 16169489 Interacts with the SFT and DSBC complexes, two subcomplexes involved in the formation of meiotic double-strand breaks. Stabilizes the SFT subcomplex on DSB sites and recruits the DSBC subcomplex onto DSB sites]
• Protein Sequence: MENYTKSTTMCGKRKPTFEIYRESDFSKITNQGTVTAFDIISNKETFSESKQLKKAKSRNVTLVDKNTKADKRYKSEKLSDYLLNQEHHKNSPKIINDVLVIGKSDGLINSFPLSQNYISSSESQTSSGNVDIIGNDNSHASPYLPKFELKSQSQSNHSNVVKNQPIKLCKKTEGGTNLDHNKSINGAVKSGTSKSANKDRIYVFYEDEEVMEYRYIFGSRMQTKNHDINANNKRKIFYQNSFSNFHLLHKIIQPNYEPASAEERKLCIEILDEVLQY

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Oops, there are no PTM records of MDE2_SCHPO !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of MDE2_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of MDE2_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of MDE2_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
REC14_SCHPO	rec14	physical	20364342
REC15_SCHPO	rec15	physical	22841486
REC14_SCHPO	rec14	physical	22841486

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.