NAB2_SCHPO - dbPTM
NAB2_SCHPO - PTM Information in dbPTM
Basic Information of Protein
UniProt ID NAB2_SCHPO
UniProt AC O13713
Protein Name Nuclear polyadenylated RNA-binding protein nab2
Gene Name nab2
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length 307
Subcellular Localization Nucleus .
Protein Description Binds to polyadenylated RNA and single-stranded DNA. It may be involved not only in RNA processing but also in transcription regulation. Believed to associate directly with nascent RNA polymerase II transcripts and remain associated during subsequent nuclear RNA processing reactions (By similarity)..
Protein Sequence MTTLLETPGYSEKLHDSIEKKLSEYGWGEEAASLADFVLVMLSNGKTQTEINEELVDLIGSDFDTSFSLWLFNQIEELEKSKNASVESVSKIDEIDFIEKESTDKSQQSFSVPETSIQPQSSQTPNITSLREEKELPTGRVGQKLKLTSQKQRFNPMAASFNYSKSVMPAAKRALTQTQEVPLCKYADKCSRANCIFAHPTPAAAPGEGMVLSSEMCASGKECKAADCVKGHPSPATVTTLPPFMSMSTIPIPCKYKPCLNPACRFIHPTKSRNMTWRPPSKTEETSLSERSFAVNESEEQLHVPSV
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
85PhosphorylationLEKSKNASVESVSKI
HHHHCCCCHHHHHHH
35.4925720772
88PhosphorylationSKNASVESVSKIDEI
HCCCCHHHHHHHHCC
29.5425720772
106PhosphorylationEKESTDKSQQSFSVP
ECCCCCCHHCCCCCC
35.9421712547
121PhosphorylationETSIQPQSSQTPNIT
CCCCCCCCCCCCCCC
30.9721712547
289PhosphorylationKTEETSLSERSFAVN
CCCCCCHHHCEEECC
30.6325720772
298PhosphorylationRSFAVNESEEQLHVP
CEEECCCCHHHHCCC
41.0324763107
306PhosphorylationEEQLHVPSV------
HHHHCCCCC------
39.0925720772

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of NAB2_SCHPO !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of NAB2_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of NAB2_SCHPO !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
PAB2_SCHPOpab2genetic
24081329
RL30B_SCHPOrpl3002physical
24081329
PRP19_SCHPOprp19physical
24081329
SPP42_SCHPOspp42physical
24081329
SN114_SCHPOcwf10physical
24081329
PRP31_SCHPOprp31physical
24081329
CWF11_SCHPOcwf11physical
24081329
SYF1_SCHPOcwf3physical
24081329
SF3B1_SCHPOprp10physical
24081329
BRR2_SCHPObrr2physical
24081329
CLF1_SCHPOcwf4physical
24081329
NOG1_SCHPOnog1physical
24081329
RSE1_SCHPOprp12physical
24081329
PRP17_SCHPOprp17physical
24081329
SMD2_SCHPOsmd2physical
24081329
CEF1_SCHPOcdc5physical
24081329
PRP45_SCHPOprp45physical
24081329
CWF17_SCHPOspf38physical
24081329
SMD1_SCHPOsmd1physical
24081329
DHX15_SCHPOprp43physical
24081329
RSMB_SCHPOsmb1physical
24081329
SMD3_SCHPOsmd3physical
24081329
PRP46_SCHPOprp5physical
24081329
RU2A_SCHPOlea1physical
24081329
SA114_SCHPOsap114physical
24081329
RUXF_SCHPOsmf1physical
24081329
SA145_SCHPOsap145physical
24081329
PRP39_SCHPOusp105physical
24081329
CWC15_SCHPOcwf15physical
24081329
CBF5_SCHPOcbf5physical
24081329
FBRL_SCHPOfib1physical
24081329
NOP56_SCHPOSPBC646.10cphysical
24081329
RRP5_SCHPOSPCC1183.07physical
24081329
NOP58_SCHPOSPAC23G3.06physical
24081329
GAR1_SCHPOgar1physical
24081329
NHP2_SCHPOnhp2physical
24081329
UTP22_SCHPOutp22physical
24081329
NOP2_SCHPOnop2physical
24081329
RENT1_SCHPOupf1physical
24081329
YE02_SCHPOmtl1physical
24081329
MMI1_SCHPOmmi1physical
24081329
MTR4_SCHPOmtr4physical
24081329
PABP_SCHPOpabpphysical
26771498
PAB2_SCHPOpab2physical
26771498

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of NAB2_SCHPO

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Related Literatures of Post-Translational Modification

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