| UniProt ID | PRP31_SCHPO | |
|---|---|---|
| UniProt AC | O42904 | |
| Protein Name | Pre-mRNA-processing factor 31 | |
| Gene Name | prp31 | |
| Organism | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast). | |
| Sequence Length | 518 | |
| Subcellular Localization | Nucleus . | |
| Protein Description | Required for spliceosome assembly where it is needed to link the U4/U6XU5 tri-snRNP to the prespliceosome complexes.. | |
| Protein Sequence | MSLADELLADLDDIEETTESTITDELGPDAKKRRLELQLEEGNGISAELENDLDITKISDSAQKLPSEVANKFNDNNENIYQLLNSTRLRDIIEGTEKYKGTEKQAITGNIEDDLEYHLIVDSNSIAMEIDDEILRLHRLVKEWYHDRFPELSSLVLNAFDYCKTVSSLLNDLDNSKTKLSFLPSATVMVIATTATTTVGKPLPDEMIKNVKNCCEAIQQLGEEKQKIIEYVQSRISVVAPNLSAVVGSTTAANLIGIAGGLTRLGKFPACNLPALGKRRLTTIGINNPAVSGDYGFLYMSEIVQKTPPDVRKQAIRMTAAKVALAARIDSIHEYPDGSFGISARKEVERKIEKLLEPPSQKPTVALPVPDDRPKRRRGGRRIRKMKEQYAVTELRRLQNRVAFGKEEAEVFNFDETEGLGMLGQEGEGKIRAVSIDSRTKLRLPKARKAQLQSMAQKNPLAASGLQSSLSFTPIQGIELVNPLLQRQQKVEEANKWFRDGVFTQIKKDSNEPKNKFS | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 464 | Phosphorylation | QKNPLAASGLQSSLS HHCCHHHHHCCCCCC | 34.13 | 29996109 | |
| 468 | Phosphorylation | LAASGLQSSLSFTPI HHHHHCCCCCCCCCC | 37.99 | 21712547 | |
| 469 | Phosphorylation | AASGLQSSLSFTPIQ HHHHCCCCCCCCCCC | 18.31 | 21712547 | |
| 471 | Phosphorylation | SGLQSSLSFTPIQGI HHCCCCCCCCCCCCH | 29.08 | 29996109 | |
| 473 | Phosphorylation | LQSSLSFTPIQGIEL CCCCCCCCCCCCHHH | 18.99 | 21712547 | |
| 504 | Phosphorylation | WFRDGVFTQIKKDSN HHHCCHHHHCCCCCC | 27.29 | 25720772 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of PRP31_SCHPO !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of PRP31_SCHPO !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of PRP31_SCHPO !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| PRP1_SCHPO | prp1 | physical | 15755920 | |
| PRP1_SCHPO | prp1 | physical | 16133344 | |
| PRP1_SCHPO | prp1 | physical | 20007600 | |
| RL29_SCHPO | rpl29 | physical | 20007600 | |
| RS27_SCHPO | rps27 | physical | 20007600 | |
| SNF5_SCHPO | snf5 | genetic | 22681890 | |
| SEC14_SCHPO | spo20 | genetic | 22681890 | |
| PRP31_SCHPO | prp31 | physical | 26771498 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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