dbPTM

CLF1_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	CLF1_SCHPO
UniProt AC	P87312
Protein Name	Pre-mRNA-splicing factor cwf4
Gene Name	cwf4
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	674
Subcellular Localization	Nucleus.
Protein Description	Involved in pre-mRNA splicing and cell cycle progression. Required for the spliceosome assembly and initiation of the DNA replication (By similarity)..
Protein Sequence	MTSEAPRVKNKNPAPIQISAEQLLREAVERQDVAFVPPKINITDLEELQEFQGRKRKEFEDAIRRNRLAMGHWMRYGQWELDQKEFARARSVFERALDVDSTYIPLWLKYIECEMKNRNINHARNLFDRAVTQLPRVDKLWYKYVYMEEMLGNITGCRQVFERWLKWEPDENCWMSYIRMERRYHENERARGIYERFVVVHPEVTNWLRWARFEEECGNAANVRQVYLAAIDALGQEFLNERFFIAFAKFEIRQKEYERARTIFKYAIDFMPRSKSMELYKEYTHFEKQFGDHLGVESTVLDKRRLQYEKLLKDSPYDYDTWLDLLKLEESAGDINTIRETYEKAIAKVPEVVEKNAWRRYVYIWLNYCLFEEIDVKDVDRARKVYQEALKLIPHKKFTFAKLWLMYAMFELRQRKIDVARKTLGRALGMCPKPKLFRGYIEFEDAIKQFDRCRILYEKWILYDPEACAPWLGYAALETKLGDSDRARALYNLAVNQPILETPELVWKAYIDFEFEEMEYGKARSIYQQLLRTAPHVKVWISFANFEIAHLEDDDEEPPNEEVASPTAVVRARNVFENALAHLRQQGLKEERVVLLEAWKQFEAMHGTEDTRKHVSSLMPQVVKKRRRLEDGSFEEYLDYLFPDTATDQGDKMRKMLELSRKWKEEMAKKKLEA

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
Oops, there are no PTM records of CLF1_SCHPO !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of CLF1_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of CLF1_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of CLF1_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
CEF1_SCHPO	cdc5	physical	10409726
MBO1_SCHPO	mto1	genetic	22681890
CDC11_SCHPO	cdc11	physical	23695164
TAS3_SCHPO	tas3	physical	26771498
CDC11_SCHPO	cdc11	physical	26771498

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of CLF1_SCHPO

Related Literatures of Post-Translational Modification