dbPTM

NOG1_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	NOG1_SCHPO
UniProt AC	O94659
Protein Name	Probable nucleolar GTP-binding protein 1
Gene Name	nog1
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	642
Subcellular Localization	Nucleus, nucleolus.
Protein Description	Involved in the biogenesis of the 60S ribosomal subunit..
Protein Sequence	MATAVFKNITPIPDVNTFLDVVLSRTQRKTPTVIRSGFKISRIRGFYGRKVKFTQDTITEKLDSILQEFPKLNDIHPFHADLLNILYDRDHLKIALSQLSTAKHLVENVARDYIRLLKYGDSLYRCKQLKRAALGRMATIIKRQKSSLEFLEQVRQHLSRLPAIDPNTRTLLVCGYPNVGKSSFMNKVTRAQVDVQPYAFTTKSLFVGHFDYKYLRWQVIDTPGILDHPLEQMNTIEMQSITAMAHLRSAVLYFMDLSEMCGYSVAAQVKLYHSIKPLFANKVTILVLNKIDAMRPEDLDQKNQELLQTIIDDGNVKVVQTSCVQDIGVMDVRTTACEALLAARVEQKLKGSRVNNVLNRIHLAEPAARDEVARPACIPDSVKTRRAYDANDPNRRILARDIEAANGGAGVYNVELRDKYILQDPSWKYDRMPELLDGKNVADFVDPEIEAKLLALDEEEERLEREGYYDSDQEIEDADEEEVLEKASRIREKNKLTMLAARQKKIKNRPVLPRTAGIRTLDELQSSLQSAGLPSDSIEERARSRARTAAANEMADGSGVDLLMNEGEEIRSKSIAPRSQSNRRESGVHAEGARSYADRLARVKQIHRNRMARASESDRHVIAAKPKHLLSGKRGNGKTQRR

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
147	Phosphorylation	IIKRQKSSLEFLEQV HHHHHHHHHHHHHHH	38.67	25720772
468	Phosphorylation	ERLEREGYYDSDQEI HHHHHCCCCCCCCCC	10.19	28889911
469	Phosphorylation	RLEREGYYDSDQEIE HHHHCCCCCCCCCCC	21.59	28889911
471	Phosphorylation	EREGYYDSDQEIEDA HHCCCCCCCCCCCCC	25.68	28889911
558	Phosphorylation	ANEMADGSGVDLLMN HHHHCCCCCCCEECC	35.87	25720772
579	Phosphorylation	SKSIAPRSQSNRRES HCCCCCCCCCCCCCC	36.58	29996109
581	Phosphorylation	SIAPRSQSNRRESGV CCCCCCCCCCCCCCC	33.28	29996109
586	Phosphorylation	SQSNRRESGVHAEGA CCCCCCCCCCCCHHH	44.28	29996109

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of NOG1_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of NOG1_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of NOG1_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of NOG1_SCHPO !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of NOG1_SCHPO

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Phosphoproteome analysis of fission yeast."; Wilson-Grady J.T., Villen J., Gygi S.P.; J. Proteome Res. 7:1088-1097(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-468 AND SER-471, ANDMASS SPECTROMETRY.	18257517 [Abstract]