SA145_SCHPO - dbPTM
SA145_SCHPO - PTM Information in dbPTM
Basic Information of Protein
UniProt ID SA145_SCHPO
UniProt AC Q9UUI3
Protein Name Pre-mRNA-splicing factor sap145
Gene Name sap145
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length 601
Subcellular Localization Nucleus . Cytoplasm .
Protein Description Involved in pre-mRNA splicing. May be involved in endoplasmic reticulum-associated protein degradation (ERAD) and required for growth at low and high temperatures (By similarity)..
Protein Sequence MYLLTRPKHCCLDFLLMAEIQTAQNPLKELEKILERNNKQKNKKSRNQVRREKKKLLREKTNSGAKLAEKNSDDKDQLTENNDNLYNDKKSNGNFYDTNKTDSVDGMVYTTIVDSVELDPNDPLIEQFKDVFNRFKADGQEKDFEDTDKGQIMYSDDEILSEGEEDALQKQQEEKLSKKKLRKLKRMTVAQLKMLSEKADVVEWWDVSSLDPLFLTHLKAYPNTVPVPRHWNQKRDYLSGQRGIERQLFELPSYIRATGIVQMRNAVHENEADMPLRQKMRERVQPKMGKLDIDYQKLHDAFFRYQTKPVLTGFGECYFEGKELEADVKEKRPGDISEELREALGIAPGAPPPWLFAMQRYGPPPSYPDLKIPGVNCPIPTGAQWGFHPGGWGKPPVDQFNRPLYGDVFGNVKPRIHAGTGSPVSTQHWGELEEFEEEESSEEEESEDVEYPTEEITERETIEEYQSASEPRSQREDLHAEPLTYFNQSNVEVDNVELRKNTQPSSDAANRDLYQVLPEKSTNISGFMGPQHQYDIPTAEDTLPQKRNAHSMLSSTNKGDVALNQSSNWQDELSELVSEQAMKVGAAKRQKTQSKRDKFRL
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
154PhosphorylationTDKGQIMYSDDEILS
CCCCCEEECHHHHHC		15.5821712547
155PhosphorylationDKGQIMYSDDEILSE
CCCCEEECHHHHHCC		22.6224763107
161PhosphorylationYSDDEILSEGEEDAL
ECHHHHHCCCHHHHH		49.5728889911
505PhosphorylationLRKNTQPSSDAANRD
HHHCCCCCCHHHCCC		30.9121712547
506PhosphorylationRKNTQPSSDAANRDL
HHCCCCCCHHHCCCH		37.6421712547
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of SA145_SCHPO !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of SA145_SCHPO !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of SA145_SCHPO !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
PUB1_SCHPOpub1genetic
22681890
REB1_SCHPOreb1genetic
22681890
SDS23_SCHPOsds23genetic
22681890
UBLH1_SCHPOuch1genetic
22681890
YCGK_SCHPOSPCC16C4.20cgenetic
22681890
MU178_SCHPOmug178genetic
22681890
YIW4_SCHPOSPAC694.04cgenetic
22681890
YF98_SCHPOnht10genetic
22681890
SNF5_SCHPOsnf5genetic
22681890
YAOF_SCHPOSPAC11D3.15genetic
22681890
ARP42_SCHPOarp42genetic
22681890
SPN4_SCHPOspn4genetic
22681890
SOL1_SCHPOsol1genetic
22681890
SET1_SCHPOset1genetic
22681890
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of SA145_SCHPO

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Related Literatures of Post-Translational Modification
Phosphorylation
ReferencePubMed
"Phosphoproteome analysis of fission yeast.";
Wilson-Grady J.T., Villen J., Gygi S.P.;
J. Proteome Res. 7:1088-1097(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-161, AND MASSSPECTROMETRY.

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