PP2B_SCHPO - dbPTM
PP2B_SCHPO - PTM Information in dbPTM
Basic Information of Protein
UniProt ID PP2B_SCHPO
UniProt AC Q12705
Protein Name Serine/threonine-protein phosphatase 2B catalytic subunit
Gene Name ppb1
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length 554
Subcellular Localization
Protein Description Calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin. Appears to be involved in cytokinesis, mating, transport, nuclear and spindle pole body positioning, and cell shape..
Protein Sequence MTSGPHNLEDPIVRAIRQKNQAPSHDFTIFVQEDGSSVSTLDRVVKNVQAPATYIPTDVEFFDINEPDKPDLHFLRNHFIREGRLSEEQTLYIIKKATEILKSEDNLIEVDAPVTVCGDIHGQYYDLMKLFEVGGNPANTQYLFLGDYVDRGYFSIECLLYLWALKIWYPKTLWLLRGNHECAHLTDYFTFKLECTHKYNIKVYEACLQSFNALPLAAIMNKQFLCVHGGLSPELHTLNDIRMINRFCEPPTHGLMCDLLWSDPLEDFGSEKSNKHFIHNNVRGCSYFYSYQAVCTFLENNNLLSVIRAHEAQDVGYRMYRKTKTTGFPSLMTIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVSEMLISMLNICSKEELYETDLKESAPTQHKQPAPSENENKADQEIDIEARRQIIKNKIMAIGRISRVFSVLREERESVSELKNVSGTQRLPAGTLMLGAEGIKNAINSFDDARKLDIQNERLPPSNSRRRSTDLKAFEEVMNSSEDDTSIDHLVERFADKKSSL
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
498PhosphorylationGIKNAINSFDDARKL
HHHHHHHHHHHHHHC		24.7624763107
533PhosphorylationAFEEVMNSSEDDTSI
HHHHHHHCCCCCCCH		19.6024763107
534PhosphorylationFEEVMNSSEDDTSID
HHHHHHCCCCCCCHH		39.7924763107
538PhosphorylationMNSSEDDTSIDHLVE
HHCCCCCCCHHHHHH		39.6521712547
539PhosphorylationNSSEDDTSIDHLVER
HCCCCCCCHHHHHHH		32.7721712547
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of PP2B_SCHPO !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of PP2B_SCHPO !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of PP2B_SCHPO !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
PMP1_SCHPOpmp1genetic
12637524
PMP1_SCHPOpmp1genetic
12931193
PMP1_SCHPOpmp1genetic
10365961
SKH1_SCHPOpek1genetic
12931193
RNC1_SCHPOrnc1genetic
12931193
AP1M1_SCHPOapm1genetic
15047861
STS5_SCHPOsts5genetic
7983142
SPM1_SCHPOpmk1genetic
10365961
MKH1_SCHPOmkh1genetic
10365961
MYO3_SCHPOmyp2genetic
12136004
PMP1_SCHPOpmp1genetic
15657058
SPM1_SCHPOpmk1genetic
17005909
SKH1_SCHPOpek1genetic
17005909
MKH1_SCHPOmkh1genetic
17005909
PCK2_SCHPOpck2genetic
17005909
PP2C1_SCHPOptc1genetic
17881729
PP2C3_SCHPOptc3genetic
17881729
PMP1_SCHPOpmp1genetic
17881729
ECM33_SCHPOecm33genetic
20032302
STS1_SCHPOsts1genetic
7983142
PP2A2_SCHPOppa2genetic
7983142
PPE1_SCHPOppe1genetic
7983142
CDS1_SCHPOcds1genetic
21336311
TEA2_SCHPOtea2genetic
21336311
TIP1_SCHPOtip1genetic
21336311
BGS1_SCHPObgs1genetic
12637524
ITS3_SCHPOits3genetic
12637524
YPT3_SCHPOypt3genetic
12637524
MCD4_SCHPOits8genetic
12637524
CDC7_SCHPOcdc7genetic
12637524
PMP1_SCHPOpmp1genetic
9427748
SPM1_SCHPOpmk1genetic
9427748
MKH1_SCHPOmkh1genetic
9427748
PCK2_SCHPOpck2genetic
9427748
PRZ1_SCHPOprz1genetic
15657058
FNTB_SCHPOcpp1genetic
17005909
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of PP2B_SCHPO

loading...

Related Literatures of Post-Translational Modification

TOP
© 2024 Institute of Bioinformatics and Systems Biology, NYCU | Designed by : BiOmics Laboratory