PPE1_SCHPO - dbPTM
PPE1_SCHPO - PTM Information in dbPTM
Basic Information of Protein
UniProt ID PPE1_SCHPO
UniProt AC P36614
Protein Name Serine/threonine-protein phosphatase ppe1
Gene Name ppe1
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length 305
Subcellular Localization Nucleus . Associated with chromatin.
Protein Description Has a role in chromosome segregation. May provide a dynamic connection between kinetochore microtubules and kinetochore chromatin. Negatively regulates mis12..
Protein Sequence MFDLDEWIATVRKCKYLPEHQLKRLCEMVKVILMEESNIQPVRTPVTVCGDIHGQFYDLLELFRVGGELPSTNYIFMGDFVDRGYFSLETFTLFMLLKARYPDKITLLRGNHESRQITQVYGFYDECQTKYGNANVWKYCCQVFDFLTLAAVIDNKILCVHGGLSPEVRTLDQIRILARAQEIPHEGSFCDLMWSDPEDIESWTVSPRGAGWLFGSKVTTEFSQINDLTLIARAHQLVQEGYKYHFADKNLVTVWSAPNYCYRCGNVASVMKVDESLEPEFRIFSAVADEDRTVPPSRKRSEYFI
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
188PhosphorylationQEIPHEGSFCDLMWS
HCCCCCCCCCHHCCC		21.5127738172
276PhosphorylationSVMKVDESLEPEFRI
EEEECCCCCCCCEEE		33.3025720772
301PhosphorylationVPPSRKRSEYFI---
CCCCCCCCCCCC---		39.4225720772
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of PPE1_SCHPO !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of PPE1_SCHPO !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of PPE1_SCHPO !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
GSK3_SCHPOgsk3genetic
12773390
PP2A2_SCHPOppa2genetic
8387356
PCK1_SCHPOpck1genetic
8387356
EKC1_SCHPOekc1physical
12773390
PP2A1_SCHPOppa1genetic
8387356
DIS3_SCHPOdis3genetic
8387356
MAG1_SCHPOmag1genetic
22681890
YAOE_SCHPOSPAC11D3.14cgenetic
22681890
KU80_SCHPOpku80genetic
22681890
MGR2_SCHPOmgr2genetic
22681890
GOS1_SCHPOgos1genetic
22681890
YGRG_SCHPOSPBC365.16genetic
22681890
MAC1_SCHPOmac1genetic
22681890
CAM2_SCHPOcam2genetic
22681890
ATP12_SCHPOatp12genetic
22681890
PNK1_SCHPOpnk1genetic
22681890
APQ12_SCHPOapq12genetic
22681890
VPS3_SCHPOvps3genetic
22681890
RM01_SCHPOSPAC1610.02cgenetic
22681890
CYSK_SCHPOcys11genetic
22681890
ATP11_SCHPOatp11genetic
22681890
TOM70_SCHPOtom70genetic
22681890
EMC1_SCHPOemc1genetic
22681890
YFE6_SCHPOgmh5genetic
22681890
RF1M_SCHPOmrf1genetic
22681890
EKC1_SCHPOekc1physical
26771498
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of PPE1_SCHPO

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Related Literatures of Post-Translational Modification

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