dbPTM

CDC16_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	CDC16_SCHPO
UniProt AC	P36618
Protein Name	Cell division control protein 16
Gene Name	cdc16
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	299
Subcellular Localization	Cytoplasm . Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body .
Protein Description	Has a dual role in the cell cycle. In mitosis, it is involved in maintenance of cdc2 kinase activity. It is subsequently required for regulation of septum formation. Could be involved in maintenance of cdc2 kinase activity by preventing, directly or indirectly, the degradation of cyclin or the dephosphorylation of 'Thr-167' of cdc2..
Protein Sequence	MPSIDCKRLQKLAPKSPENQSKCISRLRYMVMLDQVESDEGGNSSTRPYVWAVLLNAPPRNADEYIRYVRQGPSPMAQKIQNDVSRTLVVESQFHSRVSQSSLSRLLNAYVWKRGALYVQGMNVLASPFLYACKSENQAFQFFDRLLQNECPLYVLPNIDGVHRGAKLLDKCLEVLDHRLYTYLLSKGLTAKIYALPSILTLSACTAPLSEALTIWDFLFAYGIHLNILCVIAQMFIFREQLIDHPSPMTLLRTFPPLNAKNIMKITILLISKLPPELYNLLARHAWDSEAGVLIDRLT

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
16	Phosphorylation	LQKLAPKSPENQSKC HHHHCCCCHHHHHHH	36.07	24763107

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of CDC16_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of CDC16_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of CDC16_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
BYR4_SCHPO	byr4	genetic	9742395
MOB1_SCHPO	mob1	genetic	10769201
BYR4_SCHPO	byr4	genetic	9638658
CDC7_SCHPO	cdc7	genetic	9638658
DMA1_SCHPO	dma1	genetic	8978687
ZFS1_SCHPO	zfs1	genetic	10462526
CDC7_SCHPO	cdc7	genetic	11271422
SPG1_SCHPO	spg1	genetic	11271422
SID1_SCHPO	sid1	genetic	11271422
SID2_SCHPO	sid2	genetic	11271422
CDC11_SCHPO	cdc11	genetic	11271422
CDC14_SCHPO	cdc14	genetic	11271422
MOB1_SCHPO	mob1	genetic	11271422
DMA1_SCHPO	dma1	genetic	11271422
CTK1_SCHPO	lsk1	genetic	15537703
BYR4_SCHPO	byr4	physical	10196225
CDC11_SCHPO	cdc11	physical	15062098
RPB1_SCHPO	rpb1	genetic	17502918
WEE1_SCHPO	wee1	genetic	20805322
SID2_SCHPO	sid2	genetic	20805322
2ABA_SCHPO	pab1	genetic	20876564
DMA1_SCHPO	dma1	genetic	12479804
CTK3_SCHPO	lsg1	genetic	21931816
YNVD_SCHPO	far10	genetic	22119525
PTPA2_SCHPO	ypa2	genetic	22267499
PP2A2_SCHPO	ppa2	genetic	22267499
YGD1_SCHPO	far8	genetic	22119525
FAR11_SCHPO	far11	genetic	22119525
YEYA_SCHPO	csc4	genetic	22119525
2AAA_SCHPO	paa1	genetic	22119525
BYR4_SCHPO	byr4	physical	9742395
CDC7_SCHPO	cdc7	genetic	10924454
DMA1_SCHPO	dma1	genetic	10924454
BYR3_SCHPO	byr3	genetic	10924454
BYR4_SCHPO	byr4	genetic	10924454
ULP2_SCHPO	ulp2	genetic	22681890
YE08_SCHPO	SPAC17H9.08	genetic	22681890
ZRG17_SCHPO	zrg17	genetic	22681890
DSK1_SCHPO	dsk1	genetic	22681890
BYR4_SCHPO	byr4	genetic	11271422
CTK1_SCHPO	lsk1	genetic	17502918
CTK2_SCHPO	lsc1	genetic	17502918
SPG1_SCHPO	spg1	genetic	9203579
CDC11_SCHPO	cdc11	genetic	23874188

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of CDC16_SCHPO

Related Literatures of Post-Translational Modification