BYR4_SCHPO - dbPTM
BYR4_SCHPO - PTM Information in dbPTM
Basic Information of Protein
UniProt ID BYR4_SCHPO
UniProt AC Q10951
Protein Name Protein byr4
Gene Name byr4
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length 665
Subcellular Localization Cell membrane
Peripheral membrane protein . Cytoplasm .
Protein Description Has an essential role in ensuring cytokinesis and septation occur only once during mitosis. It does so by interacting with the ras1 signaling pathways, thereby suppressing them..
Protein Sequence MTEVECWDDDPDFASDVDNASLFTQSIATTSASTSVDDGFSFDDSISRLNSLSISDVPSAHSRVEQWNQQVHNLNHELSSNKNRISSNVEGYEDDFSFDEEGEEGNNEFNTLRPNKYQDADVDEFNTIRASETASQRPPIPFSSDTLKKTYLSSENDARYPSVSDSPYCESEGFSSFEDDFEIDPDTDLNSILHRKQNRMDPKASFSSVEQSSLRTPSSAHNDDGFWDDFDIDFNNETESIFRKKIRSPNTINQKHPYISSTISYQPNVHQDAKYYPLCKDIFPSLANENPHSDNPNLKYSSKTLSKRDTSSHYPETLKASSKHSSPVKGNSSISSTWTPSNLKIYHSKNSMGLMDLDALKTVASNSKYRTKPKNCKTYGDGTELDTLDELPVDYEFELKLRKKQTTKVSGTPKSKHAGSTQEWHSHTTPRSTSKHENNLNNITNSAKNEHIRSQRQHKTHAAPSKELTKESLSNDQLSVKEKRRHHKKAPTLIQNLNSPRTPKIVGKMRYNPTKHCWEGNDYAIRDFDTPISPSRPALISNISTKKGIQVVGNMVYDPTRLRWIDNSISGQEAEDPFSGFDDLEDTDSTSQYLNENSGSFNGSINSIINFPDMSEIYDVGPEFEKKQFSEDIQWRKRIDGWFFSFKNDDRSRLWELYNILNAEQ
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
51PhosphorylationDSISRLNSLSISDVP
HHHHHHHCCCHHHCC		28.2525720772
53PhosphorylationISRLNSLSISDVPSA
HHHHHCCCHHHCCCH		21.6229996109
92PhosphorylationISSNVEGYEDDFSFD
CCCCCCCCCCCCCCC		11.5929996109
97PhosphorylationEGYEDDFSFDEEGEE
CCCCCCCCCCCCCCC		38.4921712547
205PhosphorylationNRMDPKASFSSVEQS
CCCCCCCCCCHHHHH		31.6125720772
208PhosphorylationDPKASFSSVEQSSLR
CCCCCCCHHHHHHCC		27.8825720772
248PhosphorylationIFRKKIRSPNTINQK
HHHHHCCCCCCCCCC		26.4424763107
251PhosphorylationKKIRSPNTINQKHPY
HHCCCCCCCCCCCCC		25.3721712547
310PhosphorylationKTLSKRDTSSHYPET
CCCCCCCCCCCCCCH		35.8424763107
311PhosphorylationTLSKRDTSSHYPETL
CCCCCCCCCCCCCHH		21.2925720772
312PhosphorylationLSKRDTSSHYPETLK
CCCCCCCCCCCCHHH		29.1821712547
325PhosphorylationLKASSKHSSPVKGNS
HHCCCCCCCCCCCCC		39.8221712547
326PhosphorylationKASSKHSSPVKGNSS
HCCCCCCCCCCCCCC		33.1728889911
428PhosphorylationTQEWHSHTTPRSTSK
CCCCCCCCCCCCCCC		41.3221712547
432PhosphorylationHSHTTPRSTSKHENN
CCCCCCCCCCCCCCC		37.9321712547
433PhosphorylationSHTTPRSTSKHENNL
CCCCCCCCCCCCCCH		42.9725720772
434PhosphorylationHTTPRSTSKHENNLN
CCCCCCCCCCCCCHH		33.0125720772
444PhosphorylationENNLNNITNSAKNEH
CCCHHHHCHHHHHHH		25.8321712547
446PhosphorylationNLNNITNSAKNEHIR
CHHHHCHHHHHHHHH		31.7824763107
479PhosphorylationSLSNDQLSVKEKRRH
HHCCCCCCHHHHHHH		26.0525720772
492PhosphorylationRHHKKAPTLIQNLNS
HHHCCCCHHHHHCCC		41.1621712547
499PhosphorylationTLIQNLNSPRTPKIV
HHHHHCCCCCCCCCC		20.9428889911
502PhosphorylationQNLNSPRTPKIVGKM
HHCCCCCCCCCCCEE		32.1124763107
530PhosphorylationYAIRDFDTPISPSRP
EEECCCCCCCCCCCC		23.6329996109
533PhosphorylationRDFDTPISPSRPALI
CCCCCCCCCCCCHHH		20.3028889911
535PhosphorylationFDTPISPSRPALISN
CCCCCCCCCCHHHHH		44.0729996109
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of BYR4_SCHPO !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of BYR4_SCHPO !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of BYR4_SCHPO !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
SPG1_SCHPOspg1genetic
9742395
2AD1_SCHPOpar1genetic
11514436
2AD2_SCHPOpar2genetic
11514436
MOB1_SCHPOmob1genetic
10769201
CDC16_SCHPOcdc16genetic
9638658
CDC7_SCHPOcdc7genetic
9638658
SID4_SCHPOsid4physical
10805785
CDC11_SCHPOcdc11physical
11676915
SPG1_SCHPOspg1physical
9638658
CDC16_SCHPOcdc16physical
9638658
CDC16_SCHPOcdc16physical
9742395
FIN1_SCHPOfin1physical
15132994
CDC11_SCHPOcdc11physical
12546793
SPG1_SCHPOspg1physical
9742395
RAS_SCHPOras1genetic
8682866
SCD1_SCHPOscd1genetic
8682866
MOB1_SCHPOmob1genetic
24920823
CDC7_SCHPOcdc7genetic
24920823
CDC11_SCHPOcdc11genetic
24920823
SPG1_SCHPOspg1genetic
24920823
PLO1_SCHPOplo1genetic
24920823
CDC16_SCHPOcdc16physical
26771498
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of BYR4_SCHPO

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Related Literatures of Post-Translational Modification
Phosphorylation
ReferencePubMed
"Phosphoproteome analysis of fission yeast.";
Wilson-Grady J.T., Villen J., Gygi S.P.;
J. Proteome Res. 7:1088-1097(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-326, AND MASSSPECTROMETRY.

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