| UniProt ID | RAS_SCHPO | |
|---|---|---|
| UniProt AC | P08647 | |
| Protein Name | Ras-like protein 1 | |
| Gene Name | ras1 | |
| Organism | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast). | |
| Sequence Length | 219 | |
| Subcellular Localization |
Cell membrane Lipid-anchor Cytoplasmic side . |
|
| Protein Description | Participates in the process of sexual differentiation and the determination of cell shape. Essential for mating and for recognition of the mating pheromone, but not for vegetative growth. Does not regulate the intracellular cAMP level. Regulates two downstream pathways, namely the byr2/byr1/spk1 mitogen-activated protein kinase cascade and the cdc42 small G protein pathway. The former is relevant to mating and sporulation, whereas the latter is relevant to mating, cell growth and cell morphology.. | |
| Protein Sequence | MRSTYLREYKLVVVGDGGVGKSALTIQLIQSHFVDEYDPTIEDSYRKKCEIDGEGALLDVLDTAGQEEYSAMREQYMRTGEGFLLVYNITSRSSFDEISTFYQQILRVKDKDTFPVVLVANKCDLEAERVVSRAEGEQLAKSMHCLYVETSAKLRLNVEEAFYSLVRTIRRYNKSEEKGFQNKQAVQTAQVPASTAKRASAVNNSKTEDEVSTKCCVIC | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
|
|
||
* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 194 | Phosphorylation | QTAQVPASTAKRASA HHCCCCHHHHHHHHH | 23.87 | 25720772 | |
| 195 | Phosphorylation | TAQVPASTAKRASAV HCCCCHHHHHHHHHC | 38.00 | 29996109 | |
| 200 | Phosphorylation | ASTAKRASAVNNSKT HHHHHHHHHCCCCCC | 36.46 | 24763107 | |
| 205 | Phosphorylation | RASAVNNSKTEDEVS HHHHCCCCCCCCCCC | 35.43 | 21712547 | |
| 207 | Phosphorylation | SAVNNSKTEDEVSTK HHCCCCCCCCCCCCC | 48.79 | 29996109 | |
| 212 | Phosphorylation | SKTEDEVSTKCCVIC CCCCCCCCCCEEEEC | 21.80 | 29996109 | |
| 215 | S-palmitoylation | EDEVSTKCCVIC--- CCCCCCCEEEEC--- | 1.96 | 28729673 | |
| 216 | Methylation | DEVSTKCCVIC---- CCCCCCEEEEC---- | 2.17 | - | |
| 216 | Farnesylation | DEVSTKCCVIC---- CCCCCCEEEEC---- | 2.17 | - |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of RAS_SCHPO !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of RAS_SCHPO !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of RAS_SCHPO !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
loading...
