BYR1_SCHPO - dbPTM
BYR1_SCHPO - PTM Information in dbPTM
Basic Information of Protein
UniProt ID BYR1_SCHPO
UniProt AC P10506
Protein Name Protein kinase byr1
Gene Name byr1
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length 340
Subcellular Localization Cytoplasm . Localizes to the cell tips and septum forming regions.
Protein Description Serine/threonine protein kinase involved in conjugation and sporulation. It is thought that it is phosphorylated by the byr2 protein kinase and that it can phosphorylate the spk1 kinase. When bound to bob1, is involved in the regulation of sexual differentiation..
Protein Sequence MFKRRRNPKGLVLNPNASVKSSDNDHKEELINNQKSFESNVEAFMEQCAHMNRRPAWISDLDNSSLEVVRHLGEGNGGAVSLVKHRNIFMARKTVYVGSDSKLQKQILRELGVLHHCRSPYIVGFYGAFQYKNNISLCMEYMDCGSLDAILREGGPIPLDILGKIINSMVKGLIYLYNVLHIIHRDLKPSNVVVNSRGEIKLCDFGVSGELVNSVAQTFVGTSTYMSPERIRGGKYTVKSDIWSLGISIIELATQELPWSFSNIDDSIGILDLLHCIVQEEPPRLPSSFPEDLRLFVDACLHKDPTLRASPQQLCAMPYFQQALMINVDLASWASNFRSS
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
21PhosphorylationNPNASVKSSDNDHKE
CCCCCCCCCCCHHHH
40.5421712547
214PhosphorylationVSGELVNSVAQTFVG
CCHHHHHHHHHHHCC
16.02-
218PhosphorylationLVNSVAQTFVGTSTY
HHHHHHHHHCCCCCC
15.56-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of BYR1_SCHPO !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of BYR1_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of BYR1_SCHPO !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
PFD5_SCHPObob1physical
11683500
SPK1_SCHPOspk1physical
9660817
BYR2_SCHPObyr2physical
9315645
SPK1_SCHPOspk1physical
23695164
MOC3_SCHPOmoc3physical
23695164
CBH1_SCHPOcbh1physical
23695164
CBH2_SCHPOcbh2physical
23695164
BYR2_SCHPObyr2physical
23695164
AFG2_SCHPOSPBC56F2.07cphysical
23695164
WIS1_SCHPOwis1genetic
8557102
SPK1_SCHPOspk1physical
26771498
YAWC_SCHPOSPAC3F10.12cphysical
26771498
MOC3_SCHPOmoc3physical
26771498
CBH1_SCHPOcbh1physical
26771498
CBH2_SCHPOcbh2physical
26771498
BYR2_SCHPObyr2physical
26771498
AFG2_SCHPOSPBC56F2.07cphysical
26771498

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of BYR1_SCHPO

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Related Literatures of Post-Translational Modification

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