dbPTM

HSP7F_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	HSP7F_SCHPO
UniProt AC	O59838
Protein Name	Heat shock protein homolog pss1
Gene Name	pss1
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	720
Subcellular Localization	Cytoplasm .
Protein Description	Required for normal growth at various temperatures..
Protein Sequence	MSSRTNVVGIDFGNSKTVIAVARNRAIDVIVNEVSNRSTPSLVSYGERSRFLGEAAKSAEASNFRNTVGSLKRLAGRTYDDPEIKDIESNFISAKLTEVDGFVGAKVQYLNEETAFSNIQLIAAYFTKIKAIAEAELIGSVSDVVISIPAWFTDIQRRALLEAANIAGLNPLRLMNDNAAAALTYGITKTDLPEPESPRRVAIVDFGHSNYSVSIVEFSRGQFHIKSTVCDRNLGSRNMDKALIDYFAAEFKEKYKIDVLSNPKATFRLATAVERLKKVLSANANAPLNVEMIMNDIDASSFIKRSDFEELIKPLLERLTPPIEKALELAGIKKEDLYSIEMVGGCTRVPIVKEVIANYFGKGLSFTLNQDEAVARGCALSCAILSPVFRVREFHVHDVTTYPITFSWEPIPENPEEDSSLEVFSEGNPIPSTKILTFYRKAPFKLLAAYSKEAQLPGSIKQNIAQYLINDVVPNKDGDLSIVKIKVRLDLHGILVVEQAYIVEEQEVEEPVETSPEEEAEKKTDEPVKMRKVKKLVKVADLSVSVQEDRLPTEVLEKYREAEHQMIATDKLVAETVDRKNALEEYIYDTRAKLDDIYAPFTNEEESSKFKEMLTKAEDWLYEEGEDTTKAVYTAKLEDLMRVGGPIRQRYLDAEEAKRQKVQAEREAAKAATKSEAEKQKPSGKFEEGTGGRAPPPPPAEEVAPENEEVETMEIDEQKE

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
5	Phosphorylation	---MSSRTNVVGIDF ---CCCCCCEEEEEC	34.02	25720772
35	Phosphorylation	DVIVNEVSNRSTPSL HEEEECCCCCCCCCC	21.98	28889911
38	Phosphorylation	VNEVSNRSTPSLVSY EECCCCCCCCCCCHH	49.25	28889911
39	Phosphorylation	NEVSNRSTPSLVSYG ECCCCCCCCCCCHHH	17.41	28889911
58	Phosphorylation	FLGEAAKSAEASNFR HHHHHHHHHHHCCHH	26.98	24763107
70	Phosphorylation	NFRNTVGSLKRLAGR CHHHHHHHHHHHCCC	26.78	25720772
197	Phosphorylation	TDLPEPESPRRVAIV CCCCCCCCCCEEEEE	34.13	27738172
386	Phosphorylation	ALSCAILSPVFRVRE HHHHHHHCCEEEEEE	16.95	25720772

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of HSP7F_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of HSP7F_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of HSP7F_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of HSP7F_SCHPO !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of HSP7F_SCHPO

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Phosphoproteome analysis of fission yeast."; Wilson-Grady J.T., Villen J., Gygi S.P.; J. Proteome Res. 7:1088-1097(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-38 AND THR-39, AND MASSSPECTROMETRY.	18257517 [Abstract]