SRE2_SCHPO - dbPTM
SRE2_SCHPO - PTM Information in dbPTM
Basic Information of Protein
UniProt ID SRE2_SCHPO
UniProt AC O43019
Protein Name Putative transcription factor sre2
Gene Name sre2
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length 793
Subcellular Localization Cytoplasm . Nucleus . Membrane
Multi-pass membrane protein . May be released from membranes by a process known as regulated intramembrane proteolysis (RIP).
Protein Description Putative transcription factor..
Protein Sequence MCPSQHSSLKDIHRQLENTAISNPTENADPSSYVDGSNIMDFKHPSIVSSSASSSYPISHVPSVGTRGIPRSYSMASAYPYQVNSNSMDASTAFNLNQDVADKPMLARNSIDSSINTELGPLESNHWFTQAQDHSRQYSSSWDPSIDPFEVKNSLHDSTDLSITHHPHLPINHQGNTWKHANESLQSNQGPVPNTKFVGLETTQTDSYQQSSVNSVVKIEEADATYALREESGQFNTFTGAENPSISPHSLNPNFPQYTEKPALTLLQSPKQNSNYDTSNFQNSVSDSSMQFTNEGMPSPVKGIMSSDDAVAFNFSQYSTVYPQNAPENGNEFETPNKLKRTVSSPCASISSKRSYGDIAQDCSYISSKTNGGGPSDSPSSSSTSVRGSVNDSNSPISSSATFAIQSNGVEPVGLSTQEQNLSPLSKRSAHNMIEKRYRSNLNDKIAELRDAVPTLRSGYNSTTADELKGTYVPLSRKLNKATILSKATEYIKSLQSKNKKLIEENKILQKRLSEYTSVIQASLTAPSQPASLSLLGPPGNTPGHRNVPPILKRSSIGTPSQQAYFPDAPHNCHSVPQNSSYPRPPMQVNRSPIDSMQTIPHANFNEMHNAYSSRYPLKYSKSCNAVSHTSMMHPQEYGGSLPSSTVPSDYNQPQLVSPRAQADQQGLSYKNVGRAVLNGLVGLETVHMLTNPDDAGSSNRFSMSVLPISPSLHSILRFLLLLLAFLCFAMHILLTPEATLRKWASSIYLSFRLECVFISFLIFSVPIYDWGNYLNLRGKLLSELNLESGVAT
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
110PhosphorylationKPMLARNSIDSSINT
CHHHHHHCCCCCCCC
23.4029996109
139PhosphorylationQDHSRQYSSSWDPSI
HHHHHCCCCCCCCCC
15.0125720772
140PhosphorylationDHSRQYSSSWDPSID
HHHHCCCCCCCCCCC
30.4325720772
141PhosphorylationHSRQYSSSWDPSIDP
HHHCCCCCCCCCCCH
29.5625720772
265PhosphorylationYTEKPALTLLQSPKQ
CCCCCHHHHCCCCCC
27.7721712547
269PhosphorylationPALTLLQSPKQNSNY
CHHHHCCCCCCCCCC
33.7521712547
342PhosphorylationTPNKLKRTVSSPCAS
CCCHHHCCCCCCCCC
24.1321712547
344PhosphorylationNKLKRTVSSPCASIS
CHHHCCCCCCCCCCC
28.1328889911
345PhosphorylationKLKRTVSSPCASISS
HHHCCCCCCCCCCCC
21.4728889911
349PhosphorylationTVSSPCASISSKRSY
CCCCCCCCCCCCCCC
29.7125720772
351PhosphorylationSSPCASISSKRSYGD
CCCCCCCCCCCCCCH
27.5821712547
352PhosphorylationSPCASISSKRSYGDI
CCCCCCCCCCCCCHH
30.3425720772
355PhosphorylationASISSKRSYGDIAQD
CCCCCCCCCCHHHHH
36.8828889911
356PhosphorylationSISSKRSYGDIAQDC
CCCCCCCCCHHHHHC
23.8928889911
376PhosphorylationKTNGGGPSDSPSSSS
CCCCCCCCCCCCCCC
54.7325720772
378PhosphorylationNGGGPSDSPSSSSTS
CCCCCCCCCCCCCCE
30.9025720772
380PhosphorylationGGPSDSPSSSSTSVR
CCCCCCCCCCCCEEE
46.9725720772
381PhosphorylationGPSDSPSSSSTSVRG
CCCCCCCCCCCEEEC
31.5225720772
658PhosphorylationYNQPQLVSPRAQADQ
CCCCCCCCHHHHHHH
19.7727738172

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of SRE2_SCHPO !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of SRE2_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of SRE2_SCHPO !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
MU103_SCHPOmug103genetic
21504829
YLD2_SCHPOslc1genetic
21504829
SOL1_SCHPOsol1genetic
21504829
YIU1_SCHPOsaf5genetic
21504829
PCR1_SCHPOpcr1genetic
21504829
TRK1_SCHPOtrk1genetic
21504829
MU172_SCHPOmsd1genetic
21504829
NNRD_SCHPOSPCC61.03genetic
21504829
SYM1_SCHPOSPAC3G6.05genetic
21504829
CUF1_SCHPOcuf1genetic
21504829
TASP1_SCHPOSPAC823.09cgenetic
21504829
YE98_SCHPOerp2genetic
21504829
ADRL_SCHPOSPBC12C2.09cgenetic
21504829
YA01_SCHPOSPAC5H10.01genetic
21504829
YCN3_SCHPOSPCC320.03genetic
21504829
AP2A_SCHPOapl3genetic
21504829
YH73_SCHPOSPBC16G5.03genetic
21504829
FOR3_SCHPOfor3genetic
21504829
OTU2_SCHPOotu2genetic
21504829
UAF30_SCHPOspp27genetic
21504829
FT105_SCHPOftp105genetic
21504829
PRZ1_SCHPOprz1genetic
21504829
PLC1_SCHPOplc1genetic
21504829
RAF1_SCHPOraf1genetic
21504829
SKI2_SCHPOSPCC550.03cgenetic
21504829
YHZ3_SCHPOath1genetic
21504829
YJE6_SCHPOSPCC1682.06genetic
21504829
YEO2_SCHPOtco1genetic
21504829
YK18_SCHPOSPAPB1A10.08genetic
21504829
ZFS1_SCHPOzfs1genetic
21504829
SET5_SCHPOset5genetic
21504829
CAND1_SCHPOknd1genetic
21504829
ADG2_SCHPOadg2genetic
21504829
RL10B_SCHPOrpl1002genetic
21504829
YQMA_SCHPOSPCP1E11.10genetic
21504829
YDHE_SCHPOSPAC6G9.14genetic
21504829
YCRE_SCHPOtrs130genetic
21504829
RAD24_SCHPOrad24genetic
21504829
UPP2_SCHPOSPAC1399.04cgenetic
21504829
RTF_SCHPOrtf1genetic
21504829
SSN2_SCHPOmed13genetic
21504829
YIW2_SCHPOSPAC694.02genetic
21504829
EHS1_SCHPOyam8genetic
21504829
OTC_SCHPOarg3genetic
21504829
MPC1_SCHPOmpc1genetic
21504829
ERD11_SCHPOerd1genetic
21504829
PLMT_SCHPOcho1genetic
21504829
TCO89_SCHPOtco89genetic
21504829
NAGS_SCHPOarg6genetic
21504829
RL27A_SCHPOrpl2701genetic
21504829
RAF2_SCHPOraf2genetic
21504829
EST1_SCHPOest1genetic
21504829
DNI2_SCHPOdni2genetic
21504829
SHY1_SCHPOshy1genetic
21504829
YOM1_SCHPOSPBPB7E8.01genetic
21504829
YJD4_SCHPOSPCC594.04cgenetic
21504829
RL43B_SCHPOrpl4302genetic
21504829
YBI8_SCHPOoga1genetic
21504829
SDH3_SCHPOsdh3genetic
21504829
MED19_SCHPOrox3genetic
21504829
UBR1_SCHPOubr1genetic
21504829
YLA3_SCHPOSPAC1527.03genetic
21504829
CSK1_SCHPOcsk1genetic
21504829
YKW3_SCHPObop1genetic
21504829
PAC2_SCHPOpac2genetic
21504829
AROG_SCHPOSPAP8A3.07cgenetic
21504829
RSSA1_SCHPOrps001genetic
21504829
PROB_SCHPOSPAC17H9.13cgenetic
21504829
MEU10_SCHPOmeu10genetic
21504829
YBH4_SCHPOSPBC3B8.04cgenetic
21504829
YNS7_SCHPOSPBC18H10.07genetic
21504829
GPA2_SCHPOgpa2genetic
21504829
PVH1_SCHPOSPBC17A3.06genetic
21504829
YK98_SCHPOwhi2genetic
21504829
ARF6_SCHPOarf6genetic
21504829
YE87_SCHPOSPAC9G1.07genetic
21504829
YIPL_SCHPOSPAPJ691.02genetic
21504829
MDE1_SCHPOmde1genetic
21504829
PPID_SCHPOwis2genetic
21504829
OCA2_SCHPOoca2genetic
21504829
TPP1_SCHPOtpp1genetic
21504829
YG58_SCHPOSPBC56F2.08cgenetic
21504829
RLA4_SCHPOrpp202genetic
21504829
RL16A_SCHPOrpl1602genetic
21504829
YCPF_SCHPOSPCC663.15cgenetic
21504829
RS12A_SCHPOrps1201genetic
21504829
ZIP2_SCHPOzip2genetic
21504829
RLA6_SCHPOrpp203genetic
21504829
SLM1_SCHPOslm1genetic
21504829
YGT9_SCHPOSPBC4C3.09genetic
21504829
MFM2_SCHPOmfm2genetic
21504829
MPC2_SCHPOmpc2genetic
21504829
FHL1_SCHPOfhl1genetic
21504829
UBP11_SCHPOubp11genetic
21504829
EME1_SCHPOeme1genetic
21504829
ITPA_SCHPOham1genetic
21504829
UREA_SCHPOure2genetic
21504829
YI7H_SCHPOSPAC977.17genetic
21504829
RL17B_SCHPOrpl1702genetic
21504829
YDHG_SCHPOSPAC6G9.16cgenetic
21504829
POP2_SCHPOpop2genetic
21504829
ARC1_SCHPOSPAC30C2.04genetic
21504829
SVP26_SCHPOSPCC1795.10cgenetic
21504829
MED20_SCHPOmed20genetic
21504829
YDZ7_SCHPOSPAC14C4.07genetic
21504829
OTU1_SCHPOotu1genetic
21504829
TRM1_SCHPOtrm1genetic
21504829
SRB11_SCHPOsrb11genetic
21504829
YP13_SCHPOSPBP4G3.03genetic
21504829
HSP71_SCHPOssa1genetic
21504829
OYEA_SCHPOSPAC5H10.04genetic
21504829
SGT2_SCHPOSPAC1142.02cgenetic
21504829
MU123_SCHPOmug123genetic
21504829
G6PD2_SCHPOzwf2genetic
21504829
NOP53_SCHPOrrp16genetic
21504829
ETFD_SCHPOSPAC20G8.04cgenetic
21504829
YL85_SCHPOdeg1genetic
21504829
GYP10_SCHPOgyp10genetic
21504829
GTO2_SCHPOSPCC1281.07cgenetic
21504829
SFT2_SCHPOsft2genetic
21504829
ALP16_SCHPOalp16genetic
21504829
ADK_SCHPOado1genetic
21504829
TIP1_SCHPOtip1genetic
21504829
YE85_SCHPOaip1genetic
21504829
MLO3_SCHPOmlo3genetic
21504829
YKN3_SCHPOSPAPB1A11.03genetic
21504829
PSL1_SCHPOpsl1genetic
21504829
RIK1_SCHPOrik1genetic
21504829
FIO1_SCHPOfio1genetic
21504829
AMYG_SCHPOmeu17genetic
21504829
RS24A_SCHPOrps2401genetic
21504829
YKEA_SCHPOSPAC1805.10genetic
21504829
CSX2_SCHPOcnt5genetic
21504829
UREF_SCHPOSPAC29A4.13genetic
21504829
YOW5_SCHPOSPBC1861.05genetic
21504829
YLX7_SCHPOatd2genetic
21504829
MDM31_SCHPOmdm31genetic
21504829
KCC2_SCHPOcmk2genetic
21504829
YD44_SCHPOppa3genetic
21504829
PDR1_SCHPOpdr1genetic
21504829
NUP60_SCHPOnup60genetic
21504829
ATP12_SCHPOatp12genetic
21504829
TR112_SCHPOtrm112genetic
21504829
RL7B_SCHPOrpl702genetic
21504829
SODM_SCHPOSPAC1486.01genetic
21504829
YF19_SCHPOatd1genetic
21504829
MMS19_SCHPOmms19genetic
21504829
SRS2_SCHPOsrs2genetic
21504829
DEGS_SCHPOdsd1genetic
21504829
ZIP1_SCHPOzip1genetic
21504829
YCTB_SCHPOent3genetic
21504829
RAD57_SCHPOrad57genetic
21504829
YF14_SCHPOSPAC9E9.04genetic
21504829
YQE2_SCHPOSPCC576.02genetic
21504829
GAL1_SCHPOgal1genetic
21504829
BZZ1_SCHPObzz1genetic
21504829
YET4_SCHPOSPAC8C9.04genetic
21504829
ZDS1_SCHPOzds1genetic
21504829
FKBP4_SCHPOfkbp39genetic
21504829
ATP10_SCHPOatp10genetic
21504829
MUG33_SCHPOmug33genetic
21504829
ARG56_SCHPOarg11genetic
21504829
SIF3_SCHPOsif3genetic
21504829
YDQ4_SCHPOSPAC5D6.04genetic
21504829
SPO12_SCHPOspo12genetic
21504829
ANM3_SCHPOrmt3genetic
21504829
YNU4_SCHPOSPBC28E12.04genetic
21504829
PPK6_SCHPOppk6genetic
21504829
CIF1_SCHPOcif1genetic
21504829
GDH2_SCHPOgdh2genetic
21504829
YOE2_SCHPOSPBP19A11.02cgenetic
21504829
PLR1_SCHPOplr1genetic
21504829
KICH_SCHPOSPAC13G7.12cgenetic
21504829
PEX13_SCHPOpex13genetic
21504829
YI75_SCHPOSPAC977.05cgenetic
21504829
YBX5_SCHPOSPBC17D1.05genetic
21504829
ASK1_SCHPOask1genetic
21504829
MUG28_SCHPOmug28genetic
21504829
MU150_SCHPOmug150genetic
21504829
YKT4_SCHPOSPAPB1E7.04cgenetic
21504829
RSC4_SCHPOrsc4genetic
21504829
PTR2_SCHPOptr2genetic
21504829
YLO2_SCHPOtma23genetic
21504829
MEI2_SCHPOmei2genetic
21504829
DPEH1_SCHPOSPAC3A11.10cgenetic
21504829
PDS5_SCHPOpds5genetic
21504829
RAD7_SCHPOrhp7genetic
21504829
TRX2_SCHPOtrx2genetic
21504829
TPSX_SCHPOSPACUNK4.16cgenetic
21504829
SGF73_SCHPOsgf73genetic
21504829
YFZ4_SCHPOSPAC1039.04genetic
21504829
PEX5_SCHPOpex5genetic
21504829
ETT1_SCHPOnro1genetic
21504829
PFA3_SCHPOpfa3genetic
21504829
MUG58_SCHPOmug58genetic
21504829
DUS2_SCHPOdus2genetic
21504829
MED1_SCHPOpmc2genetic
21504829
VPS35_SCHPOvps35genetic
21504829
YKW3_SCHPObop1genetic
22681890
YBH4_SCHPOSPBC3B8.04cgenetic
22681890
ITPA_SCHPOham1genetic
22681890
MPC2_SCHPOmpc2genetic
22681890
YCRE_SCHPOtrs130genetic
22681890
TPP1_SCHPOtpp1genetic
22681890
YG58_SCHPOSPBC56F2.08cgenetic
22681890
FHL1_SCHPOfhl1genetic
22681890
PLMT_SCHPOcho1genetic
22681890
TCO89_SCHPOtco89genetic
22681890
YK98_SCHPOwhi2genetic
22681890
ADG2_SCHPOadg2genetic
22681890
UPP2_SCHPOSPAC1399.04cgenetic
22681890
PAC2_SCHPOpac2genetic
22681890
RAF2_SCHPOraf2genetic
22681890
UREA_SCHPOure2genetic
22681890
PROB_SCHPOSPAC17H9.13cgenetic
22681890
YIPL_SCHPOSPAPJ691.02genetic
22681890
MED19_SCHPOrox3genetic
22681890
ARF6_SCHPOarf6genetic
22681890
ZIP2_SCHPOzip2genetic
22681890
UBP11_SCHPOubp11genetic
22681890
SDH3_SCHPOsdh3genetic
22681890
UAF30_SCHPOspp27genetic
22681890
OTU2_SCHPOotu2genetic
22681890
POP2_SCHPOpop2genetic
22681890
SHY1_SCHPOshy1genetic
22681890
OTC_SCHPOarg3genetic
22681890
RTF_SCHPOrtf1genetic
22681890
YNS7_SCHPOSPBC18H10.07genetic
22681890
MEU10_SCHPOmeu10genetic
22681890
FT105_SCHPOftp105genetic
22681890
YJD4_SCHPOSPCC594.04cgenetic
22681890
NAGS_SCHPOarg6genetic
22681890
RL43B_SCHPOrpl4302genetic
22681890
GPA2_SCHPOgpa2genetic
22681890
MFM2_SCHPOmfm2genetic
22681890
SKI2_SCHPOSPCC550.03cgenetic
22681890
ZFS1_SCHPOzfs1genetic
22681890
YI7H_SCHPOSPAC977.17genetic
22681890
YDHE_SCHPOSPAC6G9.14genetic
22681890
AROG_SCHPOSPAP8A3.07cgenetic
22681890
YCPF_SCHPOSPCC663.15cgenetic
22681890
RAF1_SCHPOraf1genetic
22681890
RSSA1_SCHPOrps001genetic
22681890
RL27A_SCHPOrpl2701genetic
22681890
YE87_SCHPOSPAC9G1.07genetic
22681890
RLA6_SCHPOrpp203genetic
22681890
CAND1_SCHPOknd1genetic
22681890
EME1_SCHPOeme1genetic
22681890
ERD11_SCHPOerd1genetic
22681890
YDHG_SCHPOSPAC6G9.16cgenetic
22681890
SLM1_SCHPOslm1genetic
22681890
PPID_SCHPOwis2genetic
22681890
DNI2_SCHPOdni2genetic
22681890
OCA2_SCHPOoca2genetic
22681890
RL17B_SCHPOrpl1702genetic
22681890
RL10B_SCHPOrpl1002genetic
22681890
YHZ3_SCHPOath1genetic
22681890
PVH1_SCHPOSPBC17A3.06genetic
22681890
YQMA_SCHPOSPCP1E11.10genetic
22681890
YLA3_SCHPOSPAC1527.03genetic
22681890
MPC1_SCHPOmpc1genetic
22681890
YOM1_SCHPOSPBPB7E8.01genetic
22681890
PRZ1_SCHPOprz1genetic
22681890
CSK1_SCHPOcsk1genetic
22681890
EHS1_SCHPOyam8genetic
22681890
YJE6_SCHPOSPCC1682.06genetic
22681890
YBI8_SCHPOoga1genetic
22681890
RS12A_SCHPOrps1201genetic
22681890
YK18_SCHPOSPAPB1A10.08genetic
22681890
YIW2_SCHPOSPAC694.02genetic
22681890
YGT9_SCHPOSPBC4C3.09genetic
22681890
SSN2_SCHPOmed13genetic
22681890
GSF2_SCHPOgsf2genetic
23236291
DSC2_SCHPOdsc2physical
23760507
DSC3_SCHPOdsc3physical
23760507
DSC4_SCHPOdsc4physical
23760507

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of SRE2_SCHPO

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Related Literatures of Post-Translational Modification
Phosphorylation
ReferencePubMed
"Phosphoproteome analysis of fission yeast.";
Wilson-Grady J.T., Villen J., Gygi S.P.;
J. Proteome Res. 7:1088-1097(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-344; SER-345; SER-355AND TYR-356, AND MASS SPECTROMETRY.

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