YLA3_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: YLA3_SCHPO
• UniProt AC: Q9P6K0
• Protein Name: Uncharacterized HTH La-type RNA-binding protein C1527.03
• Gene Name: SPAC1527.03
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 475
• Subcellular Localization: Cytoplasm .
• Protein Sequence: MSHKEPSAAETSTVVHSEEDKAFCIGTGAVISEEREKEVLKNLQNSLTGKTAEENLNDEANHTSSDKSKSEDYQPSNVNVWALRKEKMIPKKHSHVKQEKRFSKSLQLQDPNVWPSPEIAEKQVEDRKLSDDSQKPLAPKANGKEKWVTITPNFTHTPISNRKSSRSRNDGSRRNGNGRRRGNYSSHGSNKRQTNYSREKDASRSIDSSNPSAEYRDDINNTFGSQTVSSANGKEVPQTSEDSSSQAPHHSSSSGHAPSQQGGNKHSYKKSDSQQSFHHKGRNTRKGQRHNNGFYRNIANNIQGPFPNYPVVVNGNGVNPYLCDVQAFLTSQLEYYFSIENLCKDMFLRKHMDDEGYVPLAFLASFNRIKSFSTDLNLLHAACKASDIIDVAIDLQSPMSIKVRRKETWSPWILPSESRLKFEMAKYPQINSSSSMSPLASSISNLTISPPFIPSSVDSIIKRDVQTEVEDKLTV

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Phosphorylation	------MSHKEPSAA ------CCCCCCCCC	43.18	24763107
7	Phosphorylation	-MSHKEPSAAETSTV -CCCCCCCCCCCCCC	41.00	21712547
11	Phosphorylation	KEPSAAETSTVVHSE CCCCCCCCCCCCCCC	25.60	29996109
12	Phosphorylation	EPSAAETSTVVHSEE CCCCCCCCCCCCCCC	15.65	21712547
13	Phosphorylation	PSAAETSTVVHSEED CCCCCCCCCCCCCCC	33.69	29996109
46	Phosphorylation	VLKNLQNSLTGKTAE HHHHHHHHHCCCCHH	17.85	24763107
48	Phosphorylation	KNLQNSLTGKTAEEN HHHHHHHCCCCHHHH	36.13	25720772
51	Phosphorylation	QNSLTGKTAEENLND HHHHCCCCHHHHCCC	40.42	24763107
64	Phosphorylation	NDEANHTSSDKSKSE CCCCCCCCCCCCCCC	29.05	21712547
65	Phosphorylation	DEANHTSSDKSKSED CCCCCCCCCCCCCCC	50.65	21712547
70	Phosphorylation	TSSDKSKSEDYQPSN CCCCCCCCCCCCCCC	42.67	27738172
116	Phosphorylation	QDPNVWPSPEIAEKQ CCCCCCCCHHHHHHH	21.32	28889911
130	Phosphorylation	QVEDRKLSDDSQKPL HHHHHCCCCCCCCCC	42.27	29996109
203	Phosphorylation	YSREKDASRSIDSSN CCHHHHHHHCCCCCC	36.37	21712547
205	Phosphorylation	REKDASRSIDSSNPS HHHHHHHCCCCCCCC	28.40	28889911
208	Phosphorylation	DASRSIDSSNPSAEY HHHHCCCCCCCCHHH	30.28	21712547
230	Phosphorylation	FGSQTVSSANGKEVP CCCCEECCCCCCCCC	22.78	21712547
239	Phosphorylation	NGKEVPQTSEDSSSQ CCCCCCCCCCCCCCC	28.19	21712547
240	Phosphorylation	GKEVPQTSEDSSSQA CCCCCCCCCCCCCCC	33.87	25720772
243	Phosphorylation	VPQTSEDSSSQAPHH CCCCCCCCCCCCCCC	28.04	25720772
245	Phosphorylation	QTSEDSSSQAPHHSS CCCCCCCCCCCCCCC	34.02	27738172
408	Phosphorylation	IKVRRKETWSPWILP EEEEECCCCCCCCCC	33.99	28889911
410	Phosphorylation	VRRKETWSPWILPSE EEECCCCCCCCCCCC	20.13	28889911
427	Phosphorylation	LKFEMAKYPQINSSS HHHHHCCCCCCCCCC	7.28	29996109
447	Phosphorylation	ASSISNLTISPPFIP HHHHHCCEECCCCCC	24.53	29996109
467	Phosphorylation	IIKRDVQTEVEDKLT HHHHHHCCHHHHCCC	41.67	25720772
474	Phosphorylation	TEVEDKLTV------ CHHHHCCCC------	29.88	25720772

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of YLA3_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of YLA3_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of YLA3_SCHPO !!

Protein-Protein Interaction

Oops, there are no PPI records of YLA3_SCHPO !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Phosphoproteome analysis of fission yeast.";
Wilson-Grady J.T., Villen J., Gygi S.P.;
J. Proteome Res. 7:1088-1097(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-408 AND SER-410, ANDMASS SPECTROMETRY.
PubMed: 18257517