MUG33_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: MUG33_SCHPO
• UniProt AC: O74472
• Protein Name: Meiotically up-regulated gene 33 protein
• Gene Name: mug33
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 336
• Subcellular Localization: Cytoplasm . Localizes to the barrier septum and the cell tip.
• Protein Description: Has a role in meiosis..
• Protein Sequence: MRIRSATPSLILLVIAIVFFVLAICTPPLANNLTLGKYGDVRFGVFGYCLNSNCSKPLVGYNSDYLDEHAKDGFRTSVIVRQRASYGLVIVPVSACICLISTIMTIFAHIGAIARSPGFFNVIGTITFFNIFITAIAFVICVITFVPHIQWPSWLVLANVGIQLIVLLLLLVARRQATRLQAKHLRRATSGSLGYNPYSLQNSSNIFSTSSRKGDLPKFSDYSAEKPMYDTISEDDGLKRGGSVSKLKPTFSNDSRSLSSYAPTVREPVPVPKSNSGFRFPFMRNKPAEQAPENPFRDPENPFKDPASAPAPNPWSINDVQANNDKKPSRFSWGRS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
189	Phosphorylation	AKHLRRATSGSLGYN HHHHHHHCCCCCCCC	31.63	25720772
190	Phosphorylation	KHLRRATSGSLGYNP HHHHHHCCCCCCCCC	25.96	29996109
192	Phosphorylation	LRRATSGSLGYNPYS HHHHCCCCCCCCCCC	20.56	29996109
195	Phosphorylation	ATSGSLGYNPYSLQN HCCCCCCCCCCCCCC	20.46	29996109
198	Phosphorylation	GSLGYNPYSLQNSSN CCCCCCCCCCCCCCC	20.55	27738172
199	Phosphorylation	SLGYNPYSLQNSSNI CCCCCCCCCCCCCCC	25.41	29996109
203	Phosphorylation	NPYSLQNSSNIFSTS CCCCCCCCCCCCCCC	16.29	29996109
204	Phosphorylation	PYSLQNSSNIFSTSS CCCCCCCCCCCCCCC	41.30	29996109
208	Phosphorylation	QNSSNIFSTSSRKGD CCCCCCCCCCCCCCC	24.47	25720772
209	Phosphorylation	NSSNIFSTSSRKGDL CCCCCCCCCCCCCCC	21.70	25720772
210	Phosphorylation	SSNIFSTSSRKGDLP CCCCCCCCCCCCCCC	27.26	25720772
211	Phosphorylation	SNIFSTSSRKGDLPK CCCCCCCCCCCCCCC	37.79	25720772
222	Phosphorylation	DLPKFSDYSAEKPMY CCCCCCCCCCCCCCC	14.47	25720772
223	Phosphorylation	LPKFSDYSAEKPMYD CCCCCCCCCCCCCCC	34.64	29996109
229	Phosphorylation	YSAEKPMYDTISEDD CCCCCCCCCCCCCCC	20.61	29996109
231	Phosphorylation	AEKPMYDTISEDDGL CCCCCCCCCCCCCCC	14.65	25720772
233	Phosphorylation	KPMYDTISEDDGLKR CCCCCCCCCCCCCCC	36.75	24763107
243	Phosphorylation	DGLKRGGSVSKLKPT CCCCCCCCCHHCCCC	26.49	25720772
250	Phosphorylation	SVSKLKPTFSNDSRS CCHHCCCCCCCCCCC	37.80	21712547
252	Phosphorylation	SKLKPTFSNDSRSLS HHCCCCCCCCCCCHH	42.05	28889911
255	Phosphorylation	KPTFSNDSRSLSSYA CCCCCCCCCCHHHCC	28.19	29996109
257	Phosphorylation	TFSNDSRSLSSYAPT CCCCCCCCHHHCCCC	36.23	28889911
259	Phosphorylation	SNDSRSLSSYAPTVR CCCCCCHHHCCCCCC	23.66	21712547
260	Phosphorylation	NDSRSLSSYAPTVRE CCCCCHHHCCCCCCC	30.52	21712547
261	Phosphorylation	DSRSLSSYAPTVREP CCCCHHHCCCCCCCC	17.14	21712547
264	Phosphorylation	SLSSYAPTVREPVPV CHHHCCCCCCCCCCC	24.83	21712547
276	Phosphorylation	VPVPKSNSGFRFPFM CCCCCCCCCCCCCCC	46.53	25720772
308	Phosphorylation	NPFKDPASAPAPNPW CCCCCCCCCCCCCCC	39.92	24763107
316	Phosphorylation	APAPNPWSINDVQAN CCCCCCCCHHHCCCC	16.87	21712547
329	Phosphorylation	ANNDKKPSRFSWGRS CCCCCCCCCCCCCCC	55.63	29996109
332	Phosphorylation	DKKPSRFSWGRS--- CCCCCCCCCCCC---	27.75	27738172

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of MUG33_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of MUG33_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of MUG33_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
MYO52_SCHPO	myo52	genetic	21652630
FOR3_SCHPO	for3	genetic	21652630
RHO3_SCHPO	rho3	genetic	21652630

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.