dbPTM

YDZ7_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	YDZ7_SCHPO
UniProt AC	O13714
Protein Name	Uncharacterized membrane protein C14C4.07
Gene Name	SPAC14C4.07
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	644
Subcellular Localization	Membrane Multi-pass membrane protein .
Protein Description
Protein Sequence	MSSHDDDHTPLLISDPSVNKPFRSRTPSPEREYCSDCPLQAKGSACNGNSHSLKHETNGASSSNNNVAKSSSHDSFKAKPKNYDSTSNSNEPISFNEPDSSNSHHNNESICNNDNCCREIARRRSLSPLLILPLNFINAFSWGMIEIPLLFLLRQELCAIHYNLDPTQLSPDDPICRLAEITTGVSKVRAAFGSLAAFLGLFSTAYYGTMGDIYGRRLVLFITVSFLLLGDLWLLYQSYAPKHPYFVLFAAALKGLGGYISTVVASQNSFVADCSKTEFRAWYLGLNFAAYHLGTALGPSLSGFIVQYTPHMYYVFYITSTFWIIYLLYVWLILPESLDVSESKEQQNKISGFSSIWRSCLEPLIILWPRSLCTEESCEFHQYDINADTHAGRRHWDVLLAAILISLTLLGAGSMGLLPLYTDYKFGWGPMKASLILSTDSFASSITLVALFPLLSKVIEKIIEKLYSSEGLFEDPSRADNTSSLQGIRNVFSYLVRPGYSRSSILRGRTADEKYTIVKRDVWNAQLGYAIALSAAVLLAVAKSDVALFTAVIIQAISNMVVPCVQSIALNGVQSEYNGRVLAAFAVFEAVALIIRGPIYAFVYTESMKVSYPNMIFFLSAVIYGCCFIIIFFMRLYRPLNRKR

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Phosphorylation	------MSSHDDDHT ------CCCCCCCCC	36.06	24763107
3	Phosphorylation	-----MSSHDDDHTP -----CCCCCCCCCC	29.63	21712547
9	Phosphorylation	SSHDDDHTPLLISDP CCCCCCCCCEECCCC	23.72	21712547
17	Phosphorylation	PLLISDPSVNKPFRS CEECCCCCCCCCCCC	43.23	29996109
24	Phosphorylation	SVNKPFRSRTPSPER CCCCCCCCCCCCCCC	40.67	21712547
26	Phosphorylation	NKPFRSRTPSPEREY CCCCCCCCCCCCCCC	29.39	21712547
28	Phosphorylation	PFRSRTPSPEREYCS CCCCCCCCCCCCCCC	38.49	28889911
61	Phosphorylation	KHETNGASSSNNNVA CCCCCCCCCCCCCCC	35.38	21712547
62	Phosphorylation	HETNGASSSNNNVAK CCCCCCCCCCCCCCC	36.23	24763107
63	Phosphorylation	ETNGASSSNNNVAKS CCCCCCCCCCCCCCC	40.87	21712547
70	Phosphorylation	SNNNVAKSSSHDSFK CCCCCCCCCCCCCCC	27.60	21712547
72	Phosphorylation	NNVAKSSSHDSFKAK CCCCCCCCCCCCCCC	38.10	21712547
75	Phosphorylation	AKSSSHDSFKAKPKN CCCCCCCCCCCCCCC	24.19	21712547
87	Phosphorylation	PKNYDSTSNSNEPIS CCCCCCCCCCCCCCC	42.06	27738172
94	Phosphorylation	SNSNEPISFNEPDSS CCCCCCCCCCCCCCC	32.50	27738172
483	Phosphorylation	PSRADNTSSLQGIRN CCCCCCCHHHHHHHH	34.99	25720772

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of YDZ7_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of YDZ7_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of YDZ7_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of YDZ7_SCHPO !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of YDZ7_SCHPO

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Phosphoproteome analysis of fission yeast."; Wilson-Grady J.T., Villen J., Gygi S.P.; J. Proteome Res. 7:1088-1097(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-28, AND MASSSPECTROMETRY.	18257517 [Abstract]