dbPTM

RHP41_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	RHP41_SCHPO
UniProt AC	Q10445
Protein Name	DNA repair protein rhp41
Gene Name	rhp41
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	638
Subcellular Localization	Nucleus .
Protein Description	Has a role in the nucleotide excision repair (NER) pathway. Acts in both transcription-coupled repair (TCR) which removes damage from the transcribed strand of active genes and in global genome repair (GGR) which removes damage in untranscribed DNA. Involved in the repair of UV-induced damages where it is involved in the removal of cyclobutane pyrimidine dimers (CPDs)..
Protein Sequence	MMSDEDNTYSDDEEWLDLDLGLPNNDIKTAPILNSSLLSSAVHGERLIQERPTHDFGDVEATVDRTVEKRSRLKITSVDRKIRLQIHQLHLLCLTYHLCTRNTWCDDNRLNYLVKYIPPGIRVSLHPSSQKSQMIRNKTFLHGLAGLVEVWKRKYKITTNGLRKPNYGLLQNNSLISESLSLEEFCKNSKLLSGSRDYGTQLFASILRNLNVPTRLVFSLQVLSFRFKGAINEASSHEIVPAWSQQMENDSSSDISESAHITSRFRKRRKIIQPSFSNLSHLDASDIVTEDTKLKVIDSPKPVFWVEAFNKAMQKWVCVDPFGDASVIGKYRRFEPASSDHLNQMTYVFAIEANGYVKDVTRKYCLHYYKILKNRVEIFPFGKAWMNRIFSKIGKPRDFYNDMDAIEDAELLRLEQSEGIPRNIQDLKDHPLFVLERHLKKNQAIKTGKSCGRINTKNGVELVYPRKYVSNGFSAEHWYRKGRIIKPGAQPLKHVKNGDKVLPLYDEEATQLYTPKPVVANIVPKNAYGNIDLYVPSMLPYGAYHCRKRCALAAAKFLEIDYAKAVVGFDFQRKYSKPKLEGVVVSKRYEEAIDLIAEEIDQEEKEAEARNVRKTCLLLWKRLITGLRIRQRVFEEYG

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
Oops, there are no PTM records of RHP41_SCHPO !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of RHP41_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of RHP41_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of RHP41_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
RHP42_SCHPO	rhp42	genetic	12807767
RHP26_SCHPO	rhp26	genetic	12807767
UVE1_SCHPO	uve1	genetic	12807767
RHP23_SCHPO	rhp23	genetic	12531030
RHP42_SCHPO	rhp42	genetic	12531030
RHP23_SCHPO	rhp23	physical	26771498

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of RHP41_SCHPO

Related Literatures of Post-Translational Modification