SLM9_SCHPO - dbPTM
SLM9_SCHPO - PTM Information in dbPTM
Basic Information of Protein
UniProt ID SLM9_SCHPO
UniProt AC O74309
Protein Name Histone transcription regulator slm9
Gene Name slm9
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length 807
Subcellular Localization Cytoplasm. Nucleus.
Protein Description Probably required for replication-independent chromatin assembly (By similarity). Required for transcriptional silencing in the outer repeat (otr) centromeric repeats and the Tf2 long terminal repeat retrotransposons. May play an indirect role in the regulation of cdc2 and/or wee1 at the G2/M stage of mitosis..
Protein Sequence MHIFVPKLLENHQFSSISSSKDFVAVSAETNVYILSKDFFYPKSSEKRIIQSLNGHKTTHLSFDSPISCIRFTYDGSCLAVATEAGTFLYHSEKWDKAFQVLSGPAYEVCWSQQGHILATSWKQISIYVKDEGLRTETIVKKTEHADSNHQPAVSIEESKEAVESTSQSSEISFKLIKVIEGHHTFVGGLAFDPMGQFLASQSFDHTLKVWKLSTFGVEKSIAKPFEQMPTGNRFLRLSWSPDGAHIASVNAVNEGAYVIAIVQRDTWTYDINLVGHQGPLECATFNPYLYEDPFQKSIIASAAHDGCVSIWNTACARPMAVIHELSCSSFVDLQWSTSGFELYGVSLDGNLMLLQFEESEFGEKMDTIHYPDDLSYFNSSRSKAHVNKNAAADRTTSPTQGQPESPSKSILLRPPPSIASSPESKRRKCPKKFVARPPVPHPTSLYSQIRIGCPYLKPKLVISKSFGTLIVKNHNQLSLLKCTFSNLDGNDCSWFSYLPNAIVLANGTSVFWAVATEDSSIYIYSPAGRLLLPPVVVAATPCFLECCGDFLCCIVSTGLLYIWNIKNFEAIHSPVSTLPLFHSNFSVSKIARGPSIEQFFVTKQGHPVAIMSDGNAFAFIRDSSSWLRVSEGWWMIGSQYWGPLASESNEESPLGFLERCTDEEIIKAGRGRFLQRLVKALMLRQGYDNYEMLVSIRHLENRLMSSAKLDLEYDFRENLILYAKKIAEEGMKDKMDELCKELLGPLRIPHNGIDTVKVGNRLWSPTIAGNNKRNLLKDIIIHTAKYRDMQRITSQYSDLLRRSALL
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
396PhosphorylationKNAAADRTTSPTQGQ
CCCCCCCCCCCCCCC
31.9721712547
397PhosphorylationNAAADRTTSPTQGQP
CCCCCCCCCCCCCCC
33.3325720772
398PhosphorylationAAADRTTSPTQGQPE
CCCCCCCCCCCCCCC
25.9021712547
400PhosphorylationADRTTSPTQGQPESP
CCCCCCCCCCCCCCC
45.1325720772
406PhosphorylationPTQGQPESPSKSILL
CCCCCCCCCCCCEEE
40.9528889911
408PhosphorylationQGQPESPSKSILLRP
CCCCCCCCCCEEECC
48.6025720772
418PhosphorylationILLRPPPSIASSPES
EEECCCCCCCCCCHH
36.2421712547
421PhosphorylationRPPPSIASSPESKRR
CCCCCCCCCCHHHHC
44.7628889911
422PhosphorylationPPPSIASSPESKRRK
CCCCCCCCCHHHHCC
24.5428889911
425PhosphorylationSIASSPESKRRKCPK
CCCCCCHHHHCCCCC
34.5421712547
765PhosphorylationKVGNRLWSPTIAGNN
EECCCCCCCCCCCCC
19.4324763107

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of SLM9_SCHPO !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of SLM9_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of SLM9_SCHPO !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
CDR1_SCHPOcdr1genetic
10835386
CDR2_SCHPOcdr2genetic
10835386
MPIP_SCHPOcdc25genetic
9843572
WEE1_SCHPOwee1genetic
9843572
HIR1_SCHPOhip1physical
15121850
HIR1_SCHPOhip1physical
16428807
HIR3_SCHPOhip3physical
16428807
ASH2_SCHPOash2genetic
18931302
H2AZ_SCHPOpht1genetic
18931302
YBAC_SCHPOrud3genetic
18931302
DOHH_SCHPOmmd1genetic
18931302
FHL1_SCHPOfhl1genetic
18931302
PLI1_SCHPOpli1genetic
18931302
SWI6_SCHPOswi6genetic
18931302
RES2_SCHPOres2genetic
18931302
PYP2_SCHPOpyp2genetic
18931302
CUL3_SCHPOcul3genetic
18931302
IES2_SCHPOies2genetic
18931302
MRC1_SCHPOmrc1genetic
18931302
YF75_SCHPOspa2genetic
18931302
PHD1_SCHPOhos2genetic
18931302
HIR1_SCHPOhip1physical
20976105
SLM9_SCHPOslm9physical
20976105
HIR3_SCHPOhip3physical
20976105
PYR1_SCHPOura1physical
20976105
HPC2_SCHPOhip4physical
20976105
SYTC_SCHPOtrs1physical
20976105
HSP90_SCHPOhsp90physical
20976105
PYRG_SCHPOcts1physical
20976105
PRS4_SCHPOrpt2physical
20976105
PRS6B_SCHPOrpt3physical
20976105
ADT_SCHPOanc1physical
20976105
HOSM_SCHPOlys4physical
20976105
TCPA_SCHPOcct1physical
20976105
TCPQ_SCHPOcct8physical
20976105
DYR_SCHPOdfr1physical
20976105
MET5_SCHPOsir1physical
20976105
TBB_SCHPOnda3physical
20976105
PUR2_SCHPOade1physical
20976105
RAD24_SCHPOrad24physical
20976105
GPD1_SCHPOgpd1physical
20976105
EF3_SCHPOtef3physical
20976105
CDC48_SCHPOcdc48physical
20976105
ILVB_SCHPOilv1physical
20976105
HSP7F_SCHPOpss1physical
20976105
RPN1_SCHPOmts4physical
20976105
VATB_SCHPOvma2physical
20976105
TBA2_SCHPOatb2physical
20976105
YGRG_SCHPOSPBC365.16physical
20976105
PRS6A_SCHPOrpt5physical
20976105
ATPB_SCHPOatp2physical
20976105
SYVM_SCHPOvrs2physical
20976105
ALF_SCHPOfba1physical
20976105
SYEC_SCHPOgus1physical
20976105
RUVB1_SCHPOrvb1physical
20976105
TCPZ_SCHPOcct6physical
20976105
DHAS_SCHPOSPCC1827.06cphysical
20976105
PGK_SCHPOpgk1physical
20976105
TCPD_SCHPOcct4physical
20976105
PRS10_SCHPOrpt4physical
20976105
HSP71_SCHPOssa1physical
20976105
PRS7_SCHPOrpt1physical
20976105
WEE1_SCHPOwee1genetic
10835386
MPIP_SCHPOcdc25genetic
10835386

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of SLM9_SCHPO

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Related Literatures of Post-Translational Modification
Phosphorylation
ReferencePubMed
"Phosphoproteome analysis of fission yeast.";
Wilson-Grady J.T., Villen J., Gygi S.P.;
J. Proteome Res. 7:1088-1097(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-406; SER-421 ANDSER-422, AND MASS SPECTROMETRY.

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