dbPTM

SYTC_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	SYTC_SCHPO
UniProt AC	P87144
Protein Name	Threonine--tRNA ligase, cytoplasmic
Gene Name	ths1
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	703
Subcellular Localization	Cytoplasm.
Protein Description
Protein Sequence	MSAAAVKGVQASLDNLSLEIPFIQHRLDLFDKLQKEYKESLATKPREEIDITLPDGKVIKGTSWETTPISIAASISKGLADRVTVAIVNGEPWDLTRPLEASCTLKLCDFNDPEGKRVFWHSSAHILGEATELSFHCHLCIGPPTDEGFFYEMGIDNGRVITNDDYSSIESYAKQAIKQKQPFERLVISKEGLLEMFRYNKYKQYIIQTKIPDGASTTVYRCGPLIDLCTGPHVPHTGRIKSFAVTKNSSSYFLGDAKNDSLQRVYGISFPDNKQMQEYKTFLAEAAKRDHRKIGRDQELFFFNEISPGSCFFLPHGARIYNTLLKYMRYQYSKRGYQEVITPNMYNVNLWKTSGHWNNYSENMFSFDIEKEKYALKPMNCPGHCVMFKSRDRSYRDLPWRVADFGVLHRNEFSGALSGLTRVRRFQQDDAHIFCTPDQVRSEIEGCFDFLKEVYGTFGFTFHLELSTRPEEKYLGDLATWDKAEAQLKAALDASGYKWELNAGDGAFYGPKIDITVFDALKRQHQCATIQLDFQLPERFQLEFHAPASAEEAKESGNNNKYTRPVMVHRAILGSLERMIAILTEHYAGKWPFWMSPRQVCIIPVSAAAYNYADKVHNILSEADIFVDTDKSDNTLPKKIRNAQLAQYNFIFVVGAEEESTNSVNVRNRDDPKKQSKGSTVAVEEVVKKLLKLKESKSLINDL

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
12	Phosphorylation	AVKGVQASLDNLSLE HHHCHHHHHHHHCCC	21.11	29996109
17	Phosphorylation	QASLDNLSLEIPFIQ HHHHHHHCCCCHHHH	30.15	29996109
167	Phosphorylation	VITNDDYSSIESYAK EEECCCCCHHHHHHH	31.66	25720772
168	Phosphorylation	ITNDDYSSIESYAKQ EECCCCCHHHHHHHH	24.93	25720772
249	Phosphorylation	SFAVTKNSSSYFLGD EEEEECCCCCCCCCC	23.40	24763107
250	Phosphorylation	FAVTKNSSSYFLGDA EEEECCCCCCCCCCC	38.15	21712547
261	Phosphorylation	LGDAKNDSLQRVYGI CCCCCCCCCCEECCC	35.48	21712547
269	Phosphorylation	LQRVYGISFPDNKQM CCEECCCCCCCHHHH	26.77	25720772
414	Phosphorylation	VLHRNEFSGALSGLT EECCCCCHHHHCCHH	19.58	25720772
418	Phosphorylation	NEFSGALSGLTRVRR CCCHHHHCCHHEEEE	31.09	25720772

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of SYTC_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of SYTC_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of SYTC_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of SYTC_SCHPO !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of SYTC_SCHPO

Related Literatures of Post-Translational Modification