| UniProt ID | CDR2_SCHPO | |
|---|---|---|
| UniProt AC | P87050 | |
| Protein Name | Mitosis inducer protein kinase cdr2 | |
| Gene Name | cdr2 | |
| Organism | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast). | |
| Sequence Length | 775 | |
| Subcellular Localization | ||
| Protein Description | Acts as a mitotic inducer. In G2 it negatively regulates wee1, a mitotic inhibitor. Also has a role in cytokinesis where it required for proper septum formation.. | |
| Protein Sequence | MSTISEVGPWELGLSLGSGGPNSSRLAKHRETGQLAVVKPIVGWSELTSSQQARIEGELVLLRLIEHPNVLQLIDVISAQEQLFVVVEYMPGGELFDCMLRKGSFTEQDTAKFLWQILCGLEYCHKLHICHRDLKPENLYLDAHGSIKIGEFGMASIQQPGKLLQTSCGSPHYASPEIIMGRSYDGCASDIWSCGIIFFALLTGKLPFDDDNIRSLLLKVCQGQFEMPSNISPQAQHLLYRMLDVDSSTRITMEQIREHPFLSCFVHPNISIPIISAPIQPIDPLIVQHLSLVFRCSDDPMPLYEKLASQSPLVEKTLYTLLSRHLHPPSSAAVDRNRAVVDDLLGTAASNGQQMDEEEIEQAINIPTLAPYPISYAAESVPRPATSASPFLTPVTTSGTFNYSFNATNPQSILQRPATTSSAVPQLPKSVTPGLAYPHDSSMLSSNYRPPSALSPRNFNVSINDPEVQLSRRATSLDMSNDFRMNENDPSIVGNLAASNFPTGMGPPRKRVTSRMSEHTGNRVVSFPRGSAFNPRVTRFNVGNEQFSNNIDNNNYNQPYANATMNNSRRLRTPSGERSMRADLSQSPASYDSLNVPKHRRRQSLFSPSSTKKKLSGSPFQPKRSFLRRLFSSEPSCKCVYASLVASELEHEILEVLRRWQLLGIGIADIIYDSVSASISARIKRQNSLNLKPVRFRISVLAEFFGSQAVFVLESGSSTTFDHLATEFQLIFEDKGFLDNLELSYFQASASRPVSRMSVSSSPFAVFRQRQSVQS | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 166 | Phosphorylation | QPGKLLQTSCGSPHY CCCCEEHHCCCCCCC | 26.42 | 25720772 | |
| 167 | Phosphorylation | PGKLLQTSCGSPHYA CCCEEHHCCCCCCCC | 11.97 | 29996109 | |
| 170 | Phosphorylation | LLQTSCGSPHYASPE EEHHCCCCCCCCCCH | 16.90 | 29996109 | |
| 309 | Phosphorylation | PLYEKLASQSPLVEK HHHHHHHHCCCHHHH | 41.44 | 28889911 | |
| 311 | Phosphorylation | YEKLASQSPLVEKTL HHHHHHCCCHHHHHH | 20.08 | 28889911 | |
| 430 | Phosphorylation | AVPQLPKSVTPGLAY CCCCCCCCCCCCCCC | 29.32 | 25720772 | |
| 432 | Phosphorylation | PQLPKSVTPGLAYPH CCCCCCCCCCCCCCC | 20.80 | 25720772 | |
| 441 | Phosphorylation | GLAYPHDSSMLSSNY CCCCCCCHHCCCCCC | 18.02 | 29996109 | |
| 442 | Phosphorylation | LAYPHDSSMLSSNYR CCCCCCHHCCCCCCC | 29.78 | 29996109 | |
| 446 | Phosphorylation | HDSSMLSSNYRPPSA CCHHCCCCCCCCCCC | 33.64 | 25720772 | |
| 452 | Phosphorylation | SSNYRPPSALSPRNF CCCCCCCCCCCCCCE | 44.52 | 29996109 | |
| 455 | Phosphorylation | YRPPSALSPRNFNVS CCCCCCCCCCCEECC | 22.87 | 25720772 | |
| 462 | Phosphorylation | SPRNFNVSINDPEVQ CCCCEECCCCCHHHH | 19.44 | 25720772 | |
| 471 | Phosphorylation | NDPEVQLSRRATSLD CCHHHHHHHHCCCCC | 11.57 | 29996109 | |
| 475 | Phosphorylation | VQLSRRATSLDMSND HHHHHHCCCCCCCCC | 28.19 | 29996109 | |
| 476 | Phosphorylation | QLSRRATSLDMSNDF HHHHHCCCCCCCCCC | 22.76 | 28889911 | |
| 480 | Phosphorylation | RATSLDMSNDFRMNE HCCCCCCCCCCCCCC | 32.68 | 29996109 | |
| 491 | Phosphorylation | RMNENDPSIVGNLAA CCCCCCHHHHHHHHH | 32.54 | 29996109 | |
| 513 | Phosphorylation | GPPRKRVTSRMSEHT CCCCHHHCHHCCCCC | 18.04 | 29996109 | |
| 514 | Phosphorylation | PPRKRVTSRMSEHTG CCCHHHCHHCCCCCC | 24.11 | 29996109 | |
| 517 | Phosphorylation | KRVTSRMSEHTGNRV HHHCHHCCCCCCCEE | 25.72 | 29996109 | |
| 526 | Phosphorylation | HTGNRVVSFPRGSAF CCCCEEEECCCCCCC | 27.03 | 25720772 | |
| 573 | Phosphorylation | NNSRRLRTPSGERSM CCCCCCCCCCCCCCC | 26.80 | 29996109 | |
| 585 | Phosphorylation | RSMRADLSQSPASYD CCCCCCCCCCCCCHH | 29.20 | 25720772 | |
| 587 | Phosphorylation | MRADLSQSPASYDSL CCCCCCCCCCCHHHC | 21.03 | 28889911 | |
| 590 | Phosphorylation | DLSQSPASYDSLNVP CCCCCCCCHHHCCCC | 32.62 | 25720772 | |
| 591 | Phosphorylation | LSQSPASYDSLNVPK CCCCCCCHHHCCCCH | 16.20 | 25720772 | |
| 593 | Phosphorylation | QSPASYDSLNVPKHR CCCCCHHHCCCCHHH | 17.38 | 25720772 | |
| 604 | Phosphorylation | PKHRRRQSLFSPSST CHHHCCCCCCCCCCC | 29.57 | 29996109 | |
| 607 | Phosphorylation | RRRQSLFSPSSTKKK HCCCCCCCCCCCCCC | 29.21 | 29996109 | |
| 609 | Phosphorylation | RQSLFSPSSTKKKLS CCCCCCCCCCCCCCC | 49.82 | 29996109 | |
| 610 | Phosphorylation | QSLFSPSSTKKKLSG CCCCCCCCCCCCCCC | 47.86 | 29996109 | |
| 616 | Phosphorylation | SSTKKKLSGSPFQPK CCCCCCCCCCCCCCC | 46.21 | 29996109 | |
| 618 | Phosphorylation | TKKKLSGSPFQPKRS CCCCCCCCCCCCCHH | 21.11 | 28889911 | |
| 632 | Phosphorylation | SFLRRLFSSEPSCKC HHHHHHHCCCCCCHH | 38.08 | 28889911 | |
| 633 | Phosphorylation | FLRRLFSSEPSCKCV HHHHHHCCCCCCHHH | 46.31 | 29996109 | |
| 755 | Phosphorylation | ASASRPVSRMSVSSS CCCCCCCCCCCCCCC | 25.58 | 29996109 | |
| 758 | Phosphorylation | SRPVSRMSVSSSPFA CCCCCCCCCCCCCCH | 20.10 | 25720772 | |
| 760 | Phosphorylation | PVSRMSVSSSPFAVF CCCCCCCCCCCCHHH | 20.14 | 25720772 | |
| 761 | Phosphorylation | VSRMSVSSSPFAVFR CCCCCCCCCCCHHHC | 39.62 | 29996109 | |
| 762 | Phosphorylation | SRMSVSSSPFAVFRQ CCCCCCCCCCHHHCH | 19.27 | 25720772 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of CDR2_SCHPO !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of CDR2_SCHPO !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of CDR2_SCHPO !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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