dbPTM

YEX1_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	YEX1_SCHPO
UniProt AC	O13855
Protein Name	Uncharacterized protein C1A6.01c
Gene Name	SPAC1A6.01c, SPAC23C4.20c
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	455
Subcellular Localization
Protein Description
Protein Sequence	MEKWTKENVLKILPVDDESAAMITSTALAVDSSEAAKDYWISLLGDSAETIEFISDFNQKRFHSTHSGNSPSIMKNKKNVTPNNNIRQKNTATSSHPSFYIANNKQKGYDEEMYKVNPASRNKSQSNNISSHEKSSKTTKNVSPGVMTSDLIPEKKSVKHNNSSSNRIEGLADIEKAIRQIEISQNINKAERRVCNCQGRKHPLNEAAPNCLNCGKIICIVEGIGPCTFCDNPVISKAQQLELIQELKHEGSRLKQAANQKRKSKTVSSKNNFQRLQNSSLHSIFLDPKQLEQKAQEAEERKNVLLNFDRTSAQRTRIIDEAADFDPTSLASDTWASPAEKALNLVRMQKAMAKKEKKKKKVLSISLSGKKVVVDQKEASSESSDEDQDELDNLTKVEGQSHSHNPKAPVIRNLPRPIYHQDLHSSHVAVPESILNKINQKWSKVQDDDGMPSML

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
65	Phosphorylation	NQKRFHSTHSGNSPS CHHHCCCCCCCCCHH	16.10	29996109
67	Phosphorylation	KRFHSTHSGNSPSIM HHCCCCCCCCCHHHH	39.49	21712547
70	Phosphorylation	HSTHSGNSPSIMKNK CCCCCCCCHHHHCCC	24.45	28889911
72	Phosphorylation	THSGNSPSIMKNKKN CCCCCCHHHHCCCCC	34.83	21712547
81	Phosphorylation	MKNKKNVTPNNNIRQ HCCCCCCCCCCCCCC	29.68	24763107
148	Phosphorylation	NVSPGVMTSDLIPEK CCCCCCCCCCCCCCC	19.38	29996109
149	Phosphorylation	VSPGVMTSDLIPEKK CCCCCCCCCCCCCCC	16.60	29996109
163	Phosphorylation	KSVKHNNSSSNRIEG CCCCCCCCCCCCHHH	40.22	21712547
164	Phosphorylation	SVKHNNSSSNRIEGL CCCCCCCCCCCHHHH	33.48	24763107
279	Phosphorylation	NFQRLQNSSLHSIFL HHHHHHHHCHHHHHC	22.70	24763107
280	Phosphorylation	FQRLQNSSLHSIFLD HHHHHHHCHHHHHCC	37.34	21712547
283	Phosphorylation	LQNSSLHSIFLDPKQ HHHHCHHHHHCCHHH	21.96	21712547
380	Phosphorylation	VVDQKEASSESSDED EECHHHHCCCCCCCC	35.41	28889911

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of YEX1_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of YEX1_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of YEX1_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of YEX1_SCHPO !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of YEX1_SCHPO

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Phosphoproteome analysis of fission yeast."; Wilson-Grady J.T., Villen J., Gygi S.P.; J. Proteome Res. 7:1088-1097(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-70 AND SER-380, AND MASSSPECTROMETRY.	18257517 [Abstract]