SSP1_SCHPO - dbPTM
SSP1_SCHPO - PTM Information in dbPTM
Basic Information of Protein
UniProt ID SSP1_SCHPO
UniProt AC P50526
Protein Name Serine/threonine-protein kinase ssp1
Gene Name ssp1
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length 652
Subcellular Localization Cytoplasm .
Protein Description Involved in actin localization and thus in polarized cell growth..
Protein Sequence MGSVNNEEKTLIEPQRLLRKNTWHPEVDDSEVPPSVFPEYPVHKAIQKTSDSFRKRNYSAGDYVIAPLGGEREGSSLTHSWTFQPGKHNQRLYSDNFQEAQRQWKRLQEWGEVKETKKIRKRFDRFSGRKYINHYEIIKELGRGMHGKVKLGRDTVTRELLAIKIIPKTERRPKLGRANASSQKEKVRREIAILKKCVHPNVVRLREVIDDPSSTKVYLVLEYMSGGEVPWTDCDSPVLSISEARQYFRDVVLGLEYLHYQGIIHRDIKPANLLLNSSNCVKISDFGVSYIANAGLNEDNDVELAKTVGTPAFFAPELCWTDLDRPRPKISEAIDVWALGVTLFCLLFGRCPFNASMEYELFDKIVNERLNIPSTPDIGEEGRDLLKRLLCKDPEQRITLVEVKLHPWTLDGLKDPEKWLQNTDPSTVSRVEVSTDEVASAISLVGRLRRKLGKLFRFRRPKARVFDSSSSVPSDSSICRPESSGNSSIGLSASELSDSFNRLAVNESQKDRERKQVHPVEMGRNSSEKKPRCDFGWDYEAFPNDNQDADDACSYNTGDSIPQVSKSINGHFETYSRTSMDTDDVASFESPNAKHEESGMPVVTFRNYENYDANPSNFHPVVPGFVSSPNLHLAGGSDTPIYCIEHSFTPTN
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
22PhosphorylationQRLLRKNTWHPEVDD
HHHHHCCCCCCCCCC		28.3424763107
49PhosphorylationVHKAIQKTSDSFRKR
HHHHHHHCCHHHHHH		22.7621712547
52PhosphorylationAIQKTSDSFRKRNYS
HHHHCCHHHHHHCCC		27.0721712547
58PhosphorylationDSFRKRNYSAGDYVI
HHHHHHCCCCCCEEE		12.1628889911
59PhosphorylationSFRKRNYSAGDYVIA
HHHHHCCCCCCEEEE		29.3528889911
63PhosphorylationRNYSAGDYVIAPLGG
HCCCCCCEEEECCCC		7.8928889911
75PhosphorylationLGGEREGSSLTHSWT
CCCCCCCCCCEEEEE		19.8829996109
76PhosphorylationGGEREGSSLTHSWTF
CCCCCCCCCEEEEEE		48.4121712547
80PhosphorylationEGSSLTHSWTFQPGK
CCCCCEEEEEECCCC		23.6829996109
82PhosphorylationSSLTHSWTFQPGKHN
CCCEEEEEECCCCCC		18.5328889911
94PhosphorylationKHNQRLYSDNFQEAQ
CCCCCCCCCCHHHHH		30.5725720772
435PhosphorylationVSRVEVSTDEVASAI
CCEEEECHHHHHHHH		41.1625720772
526PhosphorylationPVEMGRNSSEKKPRC
CCCCCCCCCCCCCCC		38.2121712547
527PhosphorylationVEMGRNSSEKKPRCD
CCCCCCCCCCCCCCC		57.9124763107
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of SSP1_SCHPO !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of SSP1_SCHPO !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of SSP1_SCHPO !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
HOG1_SCHPOsty1genetic
10233158
SNF1_SCHPOssp2genetic
22375066
WEE1_SCHPOwee1genetic
10233158
RAD24_SCHPOrad24physical
19371376
RAD25_SCHPOrad25physical
19371376
YBN1_SCHPOSPBC8E4.01cphysical
19371376
SN114_SCHPOcwf10physical
19371376
EIF3M_SCHPOSPAC1751.03physical
19371376
SDS23_SCHPOsds23genetic
19371376
MPIP_SCHPOcdc25genetic
24508166
CDR2_SCHPOcdr2genetic
24508166
RAD24_SCHPOrad24genetic
24451546
MPIP_SCHPOcdc25genetic
24451546
RAD24_SCHPOrad24physical
24451546
RAD25_SCHPOrad25physical
24451546
SRK1_SCHPOsrk1genetic
26575035
MPIP_SCHPOcdc25genetic
26575035
TWF1_SCHPOtwf1genetic
26575035
TWF1_SCHPOtwf1physical
26575035
GSK3_SCHPOgsk3genetic
28281664
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of SSP1_SCHPO

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Related Literatures of Post-Translational Modification
Phosphorylation
ReferencePubMed
"Phosphoproteome analysis of fission yeast.";
Wilson-Grady J.T., Villen J., Gygi S.P.;
J. Proteome Res. 7:1088-1097(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-58; SER-59 AND TYR-63,AND MASS SPECTROMETRY.

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