SRK1_SCHPO - dbPTM
SRK1_SCHPO - PTM Information in dbPTM
Basic Information of Protein
UniProt ID SRK1_SCHPO
UniProt AC O94547
Protein Name Serine/threonine-protein kinase srk1
Gene Name srk1
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length 580
Subcellular Localization Cytoplasm. Nucleus.
Protein Description Has a role in the regulation of meiosis via the sty1 stress-activated MAPK pathway. Inhibits nitrogen-limitation induced arrest at G1..
Protein Sequence MRFKSIQQNIEDEGKVNVREVNPDSYAERDHGYTAGIFSDAEENFGITQQVADSTQNPTSKPKSRHAHFHETVHENPSEYSRSKCKQPTNEKEYDKAIEALVAKAIVEEHSGQQFPVYKGLEQYTLLQKMGDGAFSNVYKAIHNRTGEKVAIKVVQRAQPNTDPRDPRKRQGVESHNILKEVQIMRRVKHPNIIQLLEFIQTPEYYYLVLELADGGELFHQIVRLTYFSEDLSRHVITQVAHAIRYLHEDCGVVHRDIKPENLLFDSIDFVPSRVRKYRAGDDPDKVDEGEFIPGVGAGTIGRIRLADFGLSKVVWDSHTQTPCGTMGYTAPEIVRDERYSKGVDMWALGCVLYTILCGFPPFYDESISLLTKKVSRGEYSFLSPWWDDISKSAKDLISHLLTVDPESRYDIHQFLAHPWISGSREPTFPATDAPNTAQRENPFTYDFLEPEDVAAAGSAARTPGVNSLREVFNISYAAHRMEQEKIRKRGQRGNQGIMNFMGDMDDLMEENDDYDDGTKSVEHSMKRVNLSGENDPSLASRQPAQSQQQSSQRSRNKFKGFQLNLSKATLYNRRHRQKV
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
33PhosphorylationYAERDHGYTAGIFSD
HHCCCCCCCCCCCCC		7.0429996109
34PhosphorylationAERDHGYTAGIFSDA
HCCCCCCCCCCCCCH		24.0129996109
39PhosphorylationGYTAGIFSDAEENFG
CCCCCCCCCHHHHCC		33.7125720772
48PhosphorylationAEENFGITQQVADST
HHHHCCCCHHHCCCC		17.2129996109
54PhosphorylationITQQVADSTQNPTSK
CCHHHCCCCCCCCCC		23.3529996109
55PhosphorylationTQQVADSTQNPTSKP
CHHHCCCCCCCCCCC		32.6729996109
318PhosphorylationLSKVVWDSHTQTPCG
CCEEEEECCCCCCCC		16.8429996109
322PhosphorylationVWDSHTQTPCGTMGY
EEECCCCCCCCCCCC		23.0029996109
459PhosphorylationEDVAAAGSAARTPGV
HHHHCCCHHHCCCCC		17.6527738172
463PhosphorylationAAGSAARTPGVNSLR
CCCHHHCCCCCCHHH		21.4825720772
567PhosphorylationKGFQLNLSKATLYNR
HHHHCCHHHHHHHHH		21.1224763107
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of SRK1_SCHPO !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of SRK1_SCHPO !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of SRK1_SCHPO !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
RAD24_SCHPOrad24genetic
15629716
HOG1_SCHPOsty1physical
12080074
HOG1_SCHPOsty1physical
12589433
MPIP_SCHPOcdc25physical
18272791
HOG1_SCHPOsty1physical
18272791
RAD1_SCHPOrad1genetic
20444100
YEG5_SCHPOmga2genetic
22681890
AMT1_SCHPOamt1genetic
22681890
RAF2_SCHPOraf2genetic
22681890
WTF21_SCHPOwtf21genetic
22681890
MUG33_SCHPOmug33genetic
22681890
SNF5_SCHPOsnf5genetic
22681890
ERG5_SCHPOerg5genetic
22681890
GBB_SCHPOgit5genetic
22681890
RAF1_SCHPOraf1genetic
22681890
GMA12_SCHPOgma12genetic
22681890
PTPA1_SCHPOypa1genetic
22681890
IWR1_SCHPOiwr1genetic
22681890
WEE1_SCHPOwee1genetic
26575035
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of SRK1_SCHPO

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Related Literatures of Post-Translational Modification

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