YHP6_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: YHP6_SCHPO
• UniProt AC: Q9USP7
• Protein Name: Uncharacterized protein C902.06
• Gene Name: SPBC902.06
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 397
• Subcellular Localization: Cytoplasm .
• Protein Sequence: MSEHNYQSDREVAEDPFLNYEASANQLSSNSRESTPRGSPWRAGMRSASLMTEPLEDSMYSDNNYLDNGVSFTKDENPLYSPSWPSLADANVNSMKSNNAIQEHKAAKFVSEKSLEKVSTADNNLVLQELENLRERLNQVELQLSERPSSYLGYHNNLSPYRSPNSYPSLLPSTHSPHSPAPLSTMQTALMRLRTYHPSPIILKPVEQAVNHAITLVNTSPSSVVDALCRSLAELCLGLVQEAIDASILSQQESSNSLDLVRHTPPLNYTSSVDSSPQRMASDSYGRPSLHLNDPFPSVDLQSNELSHHNVRTTLFSDDSRFHSKIHTHSTPPSQMYSAASHFRYRSDPSTRHVSNSTNKSSLHPSPTSLRVAHPIIPQRASPASQSFPSLQDTPSP

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Phosphorylation	------MSEHNYQSD ------CCCCCCCCC	47.79	29996109
29	Phosphorylation	ASANQLSSNSRESTP HHHHHHCCCCCCCCC	47.63	29996109
31	Phosphorylation	ANQLSSNSRESTPRG HHHHCCCCCCCCCCC	39.10	29996109
34	Phosphorylation	LSSNSRESTPRGSPW HCCCCCCCCCCCCCC	42.47	25720772
35	Phosphorylation	SSNSRESTPRGSPWR CCCCCCCCCCCCCCH	16.56	25720772
81	Phosphorylation	KDENPLYSPSWPSLA CCCCCCCCCCCCHHH	21.82	21712547
83	Phosphorylation	ENPLYSPSWPSLADA CCCCCCCCCCHHHHH	45.75	29996109
97	Phosphorylation	ANVNSMKSNNAIQEH HCCHHHHCCCHHHHH	27.03	21712547
159	Phosphorylation	LGYHNNLSPYRSPNS CCCCCCCCCCCCCCC	23.24	29996109
264	Phosphorylation	SLDLVRHTPPLNYTS CCCCHHCCCCCCCCC	18.94	28889911
270	Phosphorylation	HTPPLNYTSSVDSSP CCCCCCCCCCCCCCC	17.29	29996109
271	Phosphorylation	TPPLNYTSSVDSSPQ CCCCCCCCCCCCCCC	20.29	29996109
272	Phosphorylation	PPLNYTSSVDSSPQR CCCCCCCCCCCCCCH	23.34	25720772
275	Phosphorylation	NYTSSVDSSPQRMAS CCCCCCCCCCCHHCC	41.59	28889911
276	Phosphorylation	YTSSVDSSPQRMASD CCCCCCCCCCHHCCC	22.16	29996109
289	Phosphorylation	SDSYGRPSLHLNDPF CCCCCCCCCCCCCCC	27.36	29996109
328	Phosphorylation	RFHSKIHTHSTPPSQ HHCHHCCCCCCCHHH	22.46	29996109
330	Phosphorylation	HSKIHTHSTPPSQMY CHHCCCCCCCHHHHH	43.71	29996109
334	Phosphorylation	HTHSTPPSQMYSAAS CCCCCCHHHHHCHHH	28.87	29996109
355	Phosphorylation	DPSTRHVSNSTNKSS CCCCCCCCCCCCCCC	20.95	25720772
361	Phosphorylation	VSNSTNKSSLHPSPT CCCCCCCCCCCCCCC	39.95	25720772
362	Phosphorylation	SNSTNKSSLHPSPTS CCCCCCCCCCCCCCC	32.10	25720772
366	Phosphorylation	NKSSLHPSPTSLRVA CCCCCCCCCCCCCCC	30.02	28889911
368	Phosphorylation	SSLHPSPTSLRVAHP CCCCCCCCCCCCCCC	44.74	25720772
369	Phosphorylation	SLHPSPTSLRVAHPI CCCCCCCCCCCCCCC	19.98	29996109
382	Phosphorylation	PIIPQRASPASQSFP CCCCCCCCCCHHCCC	24.16	25720772
394	Phosphorylation	SFPSLQDTPSP---- CCCCCCCCCCC----	16.83	25720772
396	Phosphorylation	PSLQDTPSP------ CCCCCCCCC------	45.38	28889911

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of YHP6_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of YHP6_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of YHP6_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
ALP4_SCHPO	alp4	physical	15837798
MBO1_SCHPO	mto1	physical	15659644
MBO1_SCHPO	mto1	physical	15800064
YHP6_SCHPO	mto2	physical	24704079
MBO1_SCHPO	mto1	physical	24704079

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Phosphoproteome analysis of fission yeast.";
Wilson-Grady J.T., Villen J., Gygi S.P.;
J. Proteome Res. 7:1088-1097(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-366 AND SER-396, ANDMASS SPECTROMETRY.
PubMed: 18257517