HHP2_SCHPO - dbPTM
HHP2_SCHPO - PTM Information in dbPTM
Basic Information of Protein
UniProt ID HHP2_SCHPO
UniProt AC P40236
Protein Name Casein kinase I homolog hhp2
Gene Name hhp2
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length 400
Subcellular Localization Nucleus .
Protein Description Involved in DNA repair. May regulate the activity of protein(s) involved in double strand break repair caused by gamma rays..
Protein Sequence MTVVDIKIGNKYRIGRKIGSGSFGQIYLGLNTVNGEQVAVKLEPLKARHHQLEYEFRVYNILKGNIGIPTIRWFGVTNSYNAMVMDLLGPSLEDLFCYCGRKFTLKTVLLLADQLISRIEYVHSKSFLHRDIKPDNFLMKKHSNVVTMIDFGLAKKYRDFKTHVHIPYRDNKNLTGTARYASINTHIGIEQSRRDDLESLGYVLLYFCRGSLPWQGLQADTKEQKYQRIRDTKIGTPLEVLCKGLPEEFITYMCYTRQLSFTEKPNYAYLRKLFRDLLIRKGYQYDYVFDWMILKYQKRAAAAAAASATAPPQVTSPMVSQTQPVNPITPNYSSIPLPAERNPKTPQSFSTNIVQCASPSPLPLSFRSPVPNKDYEYIPSSLQPQYSAQLRRVLDEEPAP
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
307PhosphorylationAAAAAAASATAPPQV
HHHHHHHHCCCCCCC
22.7927738172
316PhosphorylationTAPPQVTSPMVSQTQ
CCCCCCCCCCCCCCC
16.4927738172
345PhosphorylationPAERNPKTPQSFSTN
CCCCCCCCCCCCCCC
28.0225720772
348PhosphorylationRNPKTPQSFSTNIVQ
CCCCCCCCCCCCEEE
23.5125720772
351PhosphorylationKTPQSFSTNIVQCAS
CCCCCCCCCEEECCC
27.2725720772
358PhosphorylationTNIVQCASPSPLPLS
CCEEECCCCCCCCCC
33.2725720772
360PhosphorylationIVQCASPSPLPLSFR
EEECCCCCCCCCCCC
36.2527738172
380PhosphorylationKDYEYIPSSLQPQYS
CCCCCCCHHCCHHHH
33.8424763107
381PhosphorylationDYEYIPSSLQPQYSA
CCCCCCHHCCHHHHH
26.1829996109

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of HHP2_SCHPO !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of HHP2_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of HHP2_SCHPO !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
REC8_SCHPOrec8genetic
20383139
YEG5_SCHPOmga2genetic
18818364
ELP3_SCHPOelp3genetic
18818364
POM1_SCHPOpom1genetic
18818364
MED1_SCHPOpmc2genetic
18818364
SNF5_SCHPOsnf5genetic
18818364
BU107_SCHPObun107genetic
18818364
ASH2_SCHPOash2genetic
18818364
MUB1_SCHPOSPBC31F10.10cgenetic
18818364
VPH2_SCHPOvph2genetic
18818364
PFD4_SCHPOSPAC227.05genetic
22681890
FLP1_SCHPOclp1genetic
22681890
YN1B_SCHPOSPBC577.11genetic
22681890
AMT1_SCHPOamt1genetic
22681890
RAF2_SCHPOraf2genetic
22681890
CLR4_SCHPOclr4genetic
22681890
YLO2_SCHPOtma23genetic
22681890
POM1_SCHPOpom1genetic
22681890
ARP42_SCHPOarp42genetic
22681890
PNK1_SCHPOpnk1genetic
22681890
CYB51_SCHPOSPBC29A10.16cgenetic
22681890
ELP3_SCHPOelp3genetic
22681890
RAF1_SCHPOraf1genetic
22681890
GMA12_SCHPOgma12genetic
22681890
SHR3_SCHPOpsh3genetic
22681890
TOM70_SCHPOtom70genetic
22681890
YORS_SCHPOstc1genetic
22681890
IWR1_SCHPOiwr1genetic
22681890
EMC1_SCHPOemc1genetic
22681890
MCL1_SCHPOmcl1genetic
22681890
RGA8_SCHPOrga8genetic
22681890
SREBP_SCHPOsre1physical
24327658
HHP2_SCHPOhhp2physical
24327658
HHP1_SCHPOhhp1physical
24055157
HHP2_SCHPOhhp2physical
24055157
PCP1_SCHPOpcp1physical
24055157
PPC89_SCHPOppc89physical
24055157
SID2_SCHPOsid2physical
24055157
TBG_SCHPOgtb1physical
24055157
MBO1_SCHPOmto1physical
24055157
COG6_SCHPOcog6physical
26771498

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of HHP2_SCHPO

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Related Literatures of Post-Translational Modification

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