TBG_SCHPO - dbPTM
TBG_SCHPO - PTM Information in dbPTM
Basic Information of Protein
UniProt ID TBG_SCHPO
UniProt AC P25295
Protein Name Tubulin gamma chain
Gene Name tug1
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length 446
Subcellular Localization Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body .
Protein Description Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome, suggesting that it is involved in the minus-end nucleation of microtubule assembly..
Protein Sequence MGREIITLQAGQCGNQIGSQFWQQLCLEHGIGPDGTLESFATEGVDRKDVFFYQSDDTRYIPRAILIDLEPRVVNNILSDTYGSLYNPENILITKNGGGAGNNWANGYSHAERIFEDIMDMIDREADGSDSLEGFSLLHSIAGGTGSGLGSFLLERLNDRYPKKIIQTYSVFPNSQSVSDVVVQPYNSLLALKRLTLNADSVVVLDNAALAHIAADRLHTQNPTFHQQNQLVSTVMSASTTTLRYPGYMNNDLVSIIASLIPSPRCHFLLTSYTPFTNQQVEEAKAIRKTTVLDVMRRLLLPKNQMVSVNPSKKSCFISILDIIQGEADPADVHKSLLRIRERRYASFIPWGPASIQVALSKKSPYIKTNHRVSGLMLANHTSIASLFKRTLDQYDRLRKRNAFLEQYKKEAIFEDDLNEFDSSRDVVADLINEYEACEDPNYLSL
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
308PhosphorylationLPKNQMVSVNPSKKS
CCCCCCEECCCCCCC
15.7228889911
312PhosphorylationQMVSVNPSKKSCFIS
CCEECCCCCCCCEEE
47.7328889911

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of TBG_SCHPO !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of TBG_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of TBG_SCHPO !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
TBA2_SCHPOatb2genetic
15280226
KLP5_SCHPOklp5genetic
15280226
KLP6_SCHPOklp6genetic
15280226
DIS1_SCHPOdis1genetic
15280226
TBA2_SCHPOatb2genetic
11082048
TBA1_SCHPOnda2genetic
11082048
NOT3_SCHPOnot3genetic
22737087
NOT2_SCHPOnot2genetic
22737087
RCD1_SCHPOrcd1genetic
22737087
CCR4_SCHPOccr4genetic
22737087
NACB_SCHPObtf3genetic
22737087
SWI6_SCHPOswi6genetic
22737087
FLP1_SCHPOclp1genetic
22737087
PAN3L_SCHPOpan3genetic
22737087
PAN3_SCHPOppk26genetic
22737087
CAF1_SCHPOcaf1genetic
22737087
RAD55_SCHPOrad55genetic
22737087
RAD57_SCHPOrad57genetic
22737087
EME1_SCHPOeme1genetic
22737087
MEX67_SCHPOmex67genetic
22737087
PABPX_SCHPOcrp79genetic
22737087
NAB2_SCHPOnab2genetic
22737087

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of TBG_SCHPO

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Related Literatures of Post-Translational Modification

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