HHP1_SCHPO - dbPTM
HHP1_SCHPO - PTM Information in dbPTM
Basic Information of Protein
UniProt ID HHP1_SCHPO
UniProt AC P40235
Protein Name Casein kinase I homolog hhp1
Gene Name hhp1
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length 365
Subcellular Localization Nucleus .
Protein Description Involved in DNA repair. Has a probable role in repairing alkylated DNA and may regulate the activity of protein(s) involved in double strand break repair caused by gamma rays..
Protein Sequence MALDLRIGNKYRIGRKIGSGSFGDIYLGTNVVSGEEVAIKLESTRAKHPQLEYEYRVYRILSGGVGIPFVRWFGVECDYNAMVMDLLGPSLEDLFNFCNRKFSLKTVLLLADQLISRIEFIHSKSFLHRDIKPDNFLMGIGKRGNQVNIIDFGLAKKYRDHKTHLHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLVYFCRGSLPWQGLKATTKKQKYEKIMEKKISTPTEVLCRGFPQEFSIYLNYTRSLRFDDKPDYAYLRKLFRDLFCRQSYEFDYMFDWTLKRKTQQDQQHQQQLQQQLSATPQAINPPPERSSFRNYQKQNFDEKGGDINTTVPVINDPSATGAQYINRPN
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
259PhosphorylationIYLNYTRSLRFDDKP
EEEECCCCCCCCCCC
18.9825720772
298PhosphorylationDWTLKRKTQQDQQHQ
EEHHHHHHHHHHHHH
35.1827738172
313PhosphorylationQQLQQQLSATPQAIN
HHHHHHHHCCCCCCC
26.2625720772
315PhosphorylationLQQQLSATPQAINPP
HHHHHHCCCCCCCCC
16.7429996109
326PhosphorylationINPPPERSSFRNYQK
CCCCCCCCHHHCHHH
31.9727738172
345PhosphorylationEKGGDINTTVPVIND
CCCCCCCCCCEEECC
29.5124763107
354PhosphorylationVPVINDPSATGAQYI
CEEECCCCCCCCCCC
41.1328889911
356PhosphorylationVINDPSATGAQYINR
EECCCCCCCCCCCCC
37.0725720772
360PhosphorylationPSATGAQYINRPN--
CCCCCCCCCCCCC--
10.3025720772

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of HHP1_SCHPO !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of HHP1_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of HHP1_SCHPO !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
HHP2_SCHPOhhp2genetic
16990132
HHP2_SCHPOhhp2genetic
8026462
REC8_SCHPOrec8genetic
20383139
HHP2_SCHPOhhp2genetic
20581463
REC8_SCHPOrec8physical
20581463
CDK1_SCHPOcdc2genetic
24861625
WEE1_SCHPOwee1genetic
24861625
RHP9_SCHPOcrb2genetic
24861625
CDS1_SCHPOcds1genetic
24861625
CHK1_SCHPOchk1genetic
24861625
RAD3_SCHPOrad3genetic
24861625
HHP2_SCHPOhhp2physical
24055157
CDC11_SCHPOcdc11physical
24055157
PCP1_SCHPOpcp1physical
24055157
PPC89_SCHPOppc89physical
24055157
SID4_SCHPOsid4physical
24055157
SID2_SCHPOsid2physical
24055157
BYR4_SCHPObyr4physical
24055157
TBG_SCHPOgtb1physical
24055157
CDC7_SCHPOcdc7physical
24055157
MBO1_SCHPOmto1physical
24055157
CUT12_SCHPOcut12physical
24055157
CDC31_SCHPOcdc31physical
24055157
TAS3_SCHPOtas3physical
26771498
HHP2_SCHPOhhp2genetic
25993311

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of HHP1_SCHPO

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Related Literatures of Post-Translational Modification

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