dbPTM

RHO4_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	RHO4_SCHPO
UniProt AC	Q874R1
Protein Name	GTP-binding protein rho4
Gene Name	rho4
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	203
Subcellular Localization	Membrane . Membrane-bound. Associates with the septum during mitosis.
Protein Description	Required for cell separation. Involved in the regulation of the septum degradation during cytokinesis and in the organization of F-actin patches and cytoplasmic microtubules..
Protein Sequence	MSAFKKSGSKSETSKKLVVVGDGGCGKTCLLIVFSSGTFPERYVPTVFENYITDITYGPNSKVIELALWDTAGQEEYDRLRPLSYPNSNVILLCFSIDCPASLNNVTEKWYPEVQHFCPRTPIVLVGLKADLRKDRNATEVLRTQGLTPVTYQQAQSVALSMNAPYVECSAKENTGVNEVFQLAVGLTIKKSFSFSKKSCVIL

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
200	Methylation	FSFSKKSCVIL---- CCCCCCEEEEC----	2.79	-
200	Geranylgeranylation	FSFSKKSCVIL---- CCCCCCEEEEC----	2.79	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of RHO4_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of RHO4_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of RHO4_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
TBB_SCHPO	nda3	genetic	12653963
SCD1_SCHPO	scd1	physical	14637153
ENG1_SCHPO	eng1	genetic	16215171
EXO70_SCHPO	exo70	physical	25724972
SEC8_SCHPO	sec8	physical	25724972
SPN1_SCHPO	spn1	genetic	25724972
SPN2_SCHPO	spn2	genetic	25724972
SPN3_SCHPO	spn3	genetic	25724972
SPN4_SCHPO	spn4	genetic	25724972
SPN3_SCHPO	spn3	physical	25724972

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of RHO4_SCHPO

Related Literatures of Post-Translational Modification