YAS2_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: YAS2_SCHPO
• UniProt AC: Q10138
• Protein Name: CRAL-TRIO domain-containing protein C3H8.02
• Gene Name: SPAC3H8.02
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 444
• Protein Sequence: MPEGAGRPWNLTELEEEKLKTMWSYLFKLFGITLLERTESWYTVKTHLSDDSSSSSSHRLSSVSYAKSRTRLELTSSSHGSDTRSFNDKTKNVHLERVEKIASEWDPEGLRVCFWDAVNCDDPDGLLLRFLRARKWNVEAALEMFMKTVHWRSREMNVGEIVCNADHLDKDDDFVRQLRIGKCFIFGEDKHNRPVCYIRARLHKVGDVSPESVERLTVWVMETARLILKPPIETATVVFDMTDFSMSNMDYGPLKFMIKCFEAHYPECLGECIVHKAPWLFQGVWSIIKSWLDPVVVSKVKFTRNYRDLQQYINPDNILKEFGGPNPWRYTYPEPCQNEAEALKNVEARKSLRAKKDAIAKQYEEVTMDWILNNGDMAEVKQKRRKLASQLIDAYWNLDKYIRARSVYDRMGLIAPQTSHTLLLSQPTNGDVKESMVEVTSSAT

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
33	Phosphorylation	LFKLFGITLLERTES HHHHHCCHHHEECCC	26.18	21712547
38	Phosphorylation	GITLLERTESWYTVK CCHHHEECCCEEEEE	25.62	21712547
40	Phosphorylation	TLLERTESWYTVKTH HHHEECCCEEEEEEE	25.44	28889911
42	Phosphorylation	LERTESWYTVKTHLS HEECCCEEEEEEECC	15.78	21712547
43	Phosphorylation	ERTESWYTVKTHLSD EECCCEEEEEEECCC	14.85	28889911
49	Phosphorylation	YTVKTHLSDDSSSSS EEEEEECCCCCCCCC	31.59	29996109
52	Phosphorylation	KTHLSDDSSSSSSHR EEECCCCCCCCCCCC	36.79	29996109
61	Phosphorylation	SSSSHRLSSVSYAKS CCCCCCCCCCEEECC	28.75	25720772
62	Phosphorylation	SSSHRLSSVSYAKSR CCCCCCCCCEEECCC	21.48	25720772
64	Phosphorylation	SHRLSSVSYAKSRTR CCCCCCCEEECCCCE	22.71	25720772
65	Phosphorylation	HRLSSVSYAKSRTRL CCCCCCEEECCCCEE	18.85	25720772
68	Phosphorylation	SSVSYAKSRTRLELT CCCEEECCCCEEEEE	30.61	21712547
70	Phosphorylation	VSYAKSRTRLELTSS CEEECCCCEEEEECC	46.85	25720772
75	Phosphorylation	SRTRLELTSSSHGSD CCCEEEEECCCCCCC	19.72	25720772
76	Phosphorylation	RTRLELTSSSHGSDT CCEEEEECCCCCCCC	42.33	29996109
77	Phosphorylation	TRLELTSSSHGSDTR CEEEEECCCCCCCCC	22.56	29996109
78	Phosphorylation	RLELTSSSHGSDTRS EEEEECCCCCCCCCC	31.47	29996109
81	Phosphorylation	LTSSSHGSDTRSFND EECCCCCCCCCCCCH	30.31	28889911
83	Phosphorylation	SSSHGSDTRSFNDKT CCCCCCCCCCCCHHC	29.88	29996109
85	Phosphorylation	SHGSDTRSFNDKTKN CCCCCCCCCCHHCCC	30.41	25720772
418	Phosphorylation	MGLIAPQTSHTLLLS HCCCCCCCCCEEEEC	22.78	28889911
419	Phosphorylation	GLIAPQTSHTLLLSQ CCCCCCCCCEEEECC	14.82	29996109
421	Phosphorylation	IAPQTSHTLLLSQPT CCCCCCCEEEECCCC	20.90	25720772
425	Phosphorylation	TSHTLLLSQPTNGDV CCCEEEECCCCCCCC	33.80	29996109
428	Phosphorylation	TLLLSQPTNGDVKES EEEECCCCCCCCCHH	44.17	25720772
441	Phosphorylation	ESMVEVTSSAT---- HHHEEEECCCC----	24.13	25720772

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of YAS2_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of YAS2_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of YAS2_SCHPO !!

Protein-Protein Interaction

Oops, there are no PPI records of YAS2_SCHPO !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Phosphoproteome analysis of fission yeast.";
Wilson-Grady J.T., Villen J., Gygi S.P.;
J. Proteome Res. 7:1088-1097(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-40; THR-43; SER-81 ANDTHR-418, AND MASS SPECTROMETRY.
PubMed: 18257517