dbPTM

EB1A_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	EB1A_ARATH
UniProt AC	Q7XJ60
Protein Name	Microtubule-associated protein RP/EB family member 1A
Gene Name	EB1A
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	276
Subcellular Localization	Cytoplasm, cytoskeleton, spindle pole. Cytoplasm, cytoskeleton, phragmoplast. Localizes both to the plus ends of microtubules and to the sites of nucleation during division and interphase.
Protein Description	Binds to the plus end of microtubules and regulates the dynamics of the microtubule cytoskeleton. May be involved in anchoring microtubules to their nucleation sites and/or functioning as a reservoir for distribution to the growing end. In plants, microtubule minus ends are not necessarily severed from the nucleation site and transported to the plus end of a microtubule as part of the recycling process. May play a role in endomembrane organization during polarized growth of plant cells. Interacts with the tobamovirus movement protein (MP) and may play a role in the association of MP with the microtubule system during infection..
Protein Sequence	MATNIGMMDSAYFVGRNEILTWINDRLHLNLSRVEEAASGAVQCQMLDMTFPGVVPMHKVNFDAKNEYDMIQNYKVLQDVFNKLKITKPLEINRLVKGRPLDNLEFLQWLKRFCDSINGGIMNENYNPVERRSRNGKERSVKGSNKIPKSLQTNNNHPPPNSSSVGLSKASGPKSAKAAEVQALSKELVDLKISTDLLEKERDFYFSKLRDVEILCQTPELDDLPIVVAVKKILYATDANESALEDAQEYLNQSLGVEDDEAEGNGEQLEEEKTQA

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
Oops, there are no PTM records of EB1A_ARATH !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of EB1A_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of EB1A_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of EB1A_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
EB1B_ARATH	EB1B	physical	20067996
EB1A_ARATH	EB1A	physical	20067996

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of EB1A_ARATH

Related Literatures of Post-Translational Modification