dbPTM

PP1G_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	PP1G_HUMAN
UniProt AC	P36873
Protein Name	Serine/threonine-protein phosphatase PP1-gamma catalytic subunit
Gene Name	PPP1CC
Organism	Homo sapiens (Human).
Sequence Length	323
Subcellular Localization	Cytoplasm . Nucleus. Nucleus, nucleolus . Nucleus, nucleoplasm . Nucleus speckle . Chromosome, centromere, kinetochore . Cleavage furrow . Midbody . Mitochondrion . Colocalizes with SPZ1 in the nucleus (By similarity). Colocalizes with URI1 at mitoch
Protein Description	Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets. Protein phosphatase 1 (PP1) is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Dephosphorylates RPS6KB1. Involved in regulation of ionic conductances and long-term synaptic plasticity. May play an important role in dephosphorylating substrates such as the postsynaptic density-associated Ca(2+)/calmodulin dependent protein kinase II. Component of the PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase. In balance with CSNK1D and CSNK1E, determines the circadian period length, through the regulation of the speed and rhythmicity of PER1 and PER2 phosphorylation. May dephosphorylate CSNK1D and CSNK1E. Dephosphorylates the 'Ser-418' residue of FOXP3 in regulatory T-cells (Treg) from patients with rheumatoid arthritis, thereby inactivating FOXP3 and rendering Treg cells functionally defective. [PubMed: 23396208]
Protein Sequence	MADLDKLNIDSIIQRLLEVRGSKPGKNVQLQENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVLGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAEKKKPNATRPVTPPRGMITKQAKK

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MADLDKLNI ------CCCHHHCCH	26.52	25944712
6	Ubiquitination	--MADLDKLNIDSII --CCCHHHCCHHHHH	51.21	-
6	Acetylation	--MADLDKLNIDSII --CCCHHHCCHHHHH	51.21	25038526
6 (in isoform 2)	Ubiquitination	-	51.21	21890473
11	Phosphorylation	LDKLNIDSIIQRLLE HHHCCHHHHHHHHHH	20.14	30622161
22	Phosphorylation	RLLEVRGSKPGKNVQ HHHHHHCCCCCCCCC	25.72	23186163
23 (in isoform 1)	Ubiquitination	-	61.69	21890473
23 (in isoform 2)	Ubiquitination	-	61.69	21890473
23	Ubiquitination	LLEVRGSKPGKNVQL HHHHHCCCCCCCCCC	61.69	21906983
26 (in isoform 1)	Ubiquitination	-	63.57	21890473
26	Ubiquitination	VRGSKPGKNVQLQEN HHCCCCCCCCCCCCC	63.57	21906983
26 (in isoform 2)	Ubiquitination	-	63.57	21890473
36	Methylation	QLQENEIRGLCLKSR CCCCCHHHHHHHHCH	26.33	115488427
41	Ubiquitination	EIRGLCLKSREIFLS HHHHHHHHCHHHHHC	46.61	-
41	Acetylation	EIRGLCLKSREIFLS HHHHHHHHCHHHHHC	46.61	25953088
42	Phosphorylation	IRGLCLKSREIFLSQ HHHHHHHCHHHHHCC	23.38	28450419
48	Phosphorylation	KSREIFLSQPILLEL HCHHHHHCCCEEEEE	24.14	28450419
60	Ubiquitination	LELEAPLKICGDIHG EEEHHHHHHCCCCCC	34.59	-
69	Phosphorylation	CGDIHGQYYDLLRLF CCCCCCHHHHHHHHH	11.98	28152594
70	Phosphorylation	GDIHGQYYDLLRLFE CCCCCHHHHHHHHHH	7.70	28152594
93	Phosphorylation	NYLFLGDYVDRGKQS CEEECHHHCHHCHHH	11.49	-
98	Ubiquitination	GDYVDRGKQSLETIC HHHCHHCHHHHHHHH	37.29	22053931
98 (in isoform 2)	Ubiquitination	-	37.29	21890473
98 (in isoform 1)	Ubiquitination	-	37.29	21890473
113	Acetylation	LLLAYKIKYPENFFL HHHHHHCCCCCCEEE	51.07	26051181
113 (in isoform 2)	Ubiquitination	-	51.07	21890473
113	Ubiquitination	LLLAYKIKYPENFFL HHHHHHCCCCCCEEE	51.07	21890473
113 (in isoform 1)	Ubiquitination	-	51.07	21890473
114	Phosphorylation	LLAYKIKYPENFFLL HHHHHCCCCCCEEEE	21.17	28152594
122	Methylation	PENFFLLRGNHECAS CCCEEEECCCCHHHH	46.12	-
127	S-nitrosylation	LLRGNHECASINRIY EECCCCHHHHHHHHE	2.53	19483679
127	S-nitrosocysteine	LLRGNHECASINRIY EECCCCHHHHHHHHE	2.53	-
129	Phosphorylation	RGNHECASINRIYGF CCCCHHHHHHHHEEC	31.86	30576142
132	Methylation	HECASINRIYGFYDE CHHHHHHHHEECHHH	23.10	-
134	Phosphorylation	CASINRIYGFYDECK HHHHHHHEECHHHHH	9.65	28152594
137	Phosphorylation	INRIYGFYDECKRRY HHHHEECHHHHHHHH	13.38	28152594
140	Glutathionylation	IYGFYDECKRRYNIK HEECHHHHHHHHCCC	3.67	22555962
141 (in isoform 2)	Ubiquitination	-	37.55	21890473
141	Malonylation	YGFYDECKRRYNIKL EECHHHHHHHHCCCC	37.55	26320211
141 (in isoform 1)	Ubiquitination	-	37.55	21890473
141	Acetylation	YGFYDECKRRYNIKL EECHHHHHHHHCCCC	37.55	25825284
141	Ubiquitination	YGFYDECKRRYNIKL EECHHHHHHHHCCCC	37.55	-
147 (in isoform 1)	Ubiquitination	-	44.66	21890473
147 (in isoform 2)	Ubiquitination	-	44.66	21890473
147	Acetylation	CKRRYNIKLWKTFTD HHHHHCCCCCHHHHH	44.66	23749302
147	Ubiquitination	CKRRYNIKLWKTFTD HHHHHCCCCCHHHHH	44.66	-
150 (in isoform 2)	Ubiquitination	-	44.17	-
150	Malonylation	RYNIKLWKTFTDCFN HHCCCCCHHHHHHCC	44.17	26320211
150	Ubiquitination	RYNIKLWKTFTDCFN HHCCCCCHHHHHHCC	44.17	-
155	S-nitrosylation	LWKTFTDCFNCLPIA CCHHHHHHCCCCHHH	2.10	19483679
155	S-nitrosocysteine	LWKTFTDCFNCLPIA CCHHHHHHCCCCHHH	2.10	-
158	S-nitrosylation	TFTDCFNCLPIAAIV HHHHHCCCCHHHHHC	2.10	19483679
158	S-nitrosocysteine	TFTDCFNCLPIAAIV HHHHHCCCCHHHHHC	2.10	-
158	Glutathionylation	TFTDCFNCLPIAAIV HHHHHCCCCHHHHHC	2.10	22555962
177	Phosphorylation	FCCHGGLSPDLQSME EECCCCCCCCHHHHH	21.46	30622161
182	Phosphorylation	GLSPDLQSMEQIRRI CCCCCHHHHHHHHHH	31.42	26437602
183	Sulfoxidation	LSPDLQSMEQIRRIM CCCCHHHHHHHHHHH	2.57	30846556
238 (in isoform 2)	Ubiquitination	-	40.75	21890473
238	Acetylation	VVAKFLHKHDLDLIC HHHHHHCCCCHHHHH	40.75	25825284
238	Ubiquitination	VVAKFLHKHDLDLIC HHHHHHCCCCHHHHH	40.75	-
238 (in isoform 1)	Ubiquitination	-	40.75	21890473
245	S-nitrosocysteine	KHDLDLICRAHQVVE CCCHHHHHHHHHHHH	4.01	-
245	Glutathionylation	KHDLDLICRAHQVVE CCCHHHHHHHHHHHH	4.01	22555962
245	S-nitrosylation	KHDLDLICRAHQVVE CCCHHHHHHHHHHHH	4.01	19483679
255	Phosphorylation	HQVVEDGYEFFAKRQ HHHHHHCHHHHHHCC	23.14	28796482
260	Acetylation	DGYEFFAKRQLVTLF HCHHHHHHCCEEECC	35.20	23954790
260	Ubiquitination	DGYEFFAKRQLVTLF HCHHHHHHCCEEECC	35.20	21890473
260 (in isoform 1)	Ubiquitination	-	35.20	21890473
260 (in isoform 2)	Ubiquitination	-	35.20	21890473
303 (in isoform 1)	Ubiquitination	-	55.35	21890473
303 (in isoform 2)	Ubiquitination	-	55.35	21890473
303	Ubiquitination	LKPAEKKKPNATRPV CCHHHCCCCCCCCCC	55.35	2190698
307	Phosphorylation	EKKKPNATRPVTPPR HCCCCCCCCCCCCCC	41.99	30266825
311 (in isoform 2)	Phosphorylation	-	30.20	28985074
311	Phosphorylation	PNATRPVTPPRGMIT CCCCCCCCCCCCCCC	30.20	30266825
317 (in isoform 2)	Phosphorylation	-	4.91	30622161
318	Phosphorylation	TPPRGMITKQAKK-- CCCCCCCCCCCCC--	14.28	10880350
319	Acetylation	PPRGMITKQAKK--- CCCCCCCCCCCC---	37.02	25953088
319	Ubiquitination	PPRGMITKQAKK--- CCCCCCCCCCCC---	37.02	-
322	Methylation	GMITKQAKK------ CCCCCCCCC------	57.43	116252267
336 (in isoform 2)	Phosphorylation	-		27642862

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
307	T	Phosphorylation	Kinase	NEK2	P51955	PSP
318	T	Phosphorylation	Kinase	NEK2	P51955	PSP

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of PP1G_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of PP1G_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
SNF5_HUMAN	SMARCB1	genetic	12016208
HDAC6_HUMAN	HDAC6	physical	14670976
HDAC1_HUMAN	HDAC1	physical	14670976
HDA10_HUMAN	HDAC10	physical	14670976
PR15A_HUMAN	PPP1R15A	physical	14670976
HDAC1_HUMAN	HDAC1	physical	12567184
NCOR1_HUMAN	NCOR1	physical	12410313
TIF1B_HUMAN	TRIM28	physical	20424263
WDR82_HUMAN	WDR82	physical	20516061
TOX4_HUMAN	TOX4	physical	20516061
PP1RA_HUMAN	PPP1R10	physical	20516061
EI2BE_RAT	Eif2b5	physical	12624094
NONO_HUMAN	NONO	physical	21566083
PDE6B_HUMAN	PDE6B	physical	17683050
TERA_HUMAN	VCP	physical	17683050
LMNA_HUMAN	LMNA	physical	17683050
GRP78_HUMAN	HSPA5	physical	17683050
HSP7C_HUMAN	HSPA8	physical	17683050
ENOG_HUMAN	ENO2	physical	17683050
ACTB_HUMAN	ACTB	physical	17683050
SIAH2_HUMAN	SIAH2	physical	17683050
NFL_HUMAN	NEFL	physical	17683050
PPR1B_HUMAN	PPP1R1B	physical	17683050
KCRB_HUMAN	CKB	physical	17683050
ATM_HUMAN	ATM	physical	17274640
BCL2_HUMAN	BCL2	physical	17274640
EIF2A_HUMAN	EIF2A	physical	17274640
LBR_HUMAN	LBR	physical	17274640
CDN2A_HUMAN	CDKN2A	physical	17274640
ARF_HUMAN	CDKN2A	physical	17274640
B2CL1_HUMAN	BCL2L1	physical	17274640
UB2R1_HUMAN	CDC34	physical	17274640
CDK1_HUMAN	CDK1	physical	17274640
CDK2_HUMAN	CDK2	physical	17274640
CCNB1_HUMAN	CCNB1	physical	17274640
CCND1_HUMAN	CCND1	physical	17274640
CCND3_HUMAN	CCND3	physical	17274640
HSP74_HUMAN	HSPA4	physical	17274640
MAX_HUMAN	MAX	physical	17274640
SKP1_HUMAN	SKP1	physical	17274640
PCNA_HUMAN	PCNA	physical	17274640
ESR1_HUMAN	ESR1	physical	17274640
P53_HUMAN	TP53	physical	17274640
AKT1_HUMAN	AKT1	physical	17274640
BIRC5_HUMAN	BIRC5	physical	17274640
AURKA_HUMAN	AURKA	physical	11551964
IPP2_HUMAN	PPP1R2	physical	8119416
A4_HUMAN	APP	physical	21832049
PP1R8_HUMAN	PPP1R8	physical	22939629
BMPR2_HUMAN	BMPR2	physical	23080069
GOGA7_HUMAN	GOLGA7	physical	23080069
IL3RA_HUMAN	IL3RA	physical	23080069
RANB9_HUMAN	RANBP9	physical	23080069
LMTK1_HUMAN	AATK	physical	23080069
ACAD8_HUMAN	ACAD8	physical	23080069
ABT1_HUMAN	ABT1	physical	23080069
B4GA1_HUMAN	B4GAT1	physical	23080069
BTBDA_HUMAN	BTBD10	physical	23080069
CO059_HUMAN	C15orf59	physical	23080069
C1QA_HUMAN	C1QA	physical	23080069
CLMN_HUMAN	CLMN	physical	23080069
CLH1_HUMAN	CLTC	physical	23080069
CNST_HUMAN	CNST	physical	23080069
CSN5_HUMAN	COPS5	physical	23080069
CSRN1_HUMAN	CSRNP1	physical	23080069
DEAF1_HUMAN	DEAF1	physical	23080069
ELP4_HUMAN	ELP4	physical	23080069
FRIL_HUMAN	FTL	physical	23080069
FXYD6_HUMAN	FXYD6	physical	23080069
HMGN1_HUMAN	HMGN1	physical	23080069
KCD20_HUMAN	KCTD20	physical	23080069
CE126_HUMAN	KIAA1377	physical	23080069
LMTK2_HUMAN	LMTK2	physical	23080069
NAPEP_HUMAN	NAPEPLD	physical	23080069
NEK2_HUMAN	NEK2	physical	23080069
NUAK1_HUMAN	NUAK1	physical	23080069
PHAR4_HUMAN	PHACTR4	physical	23080069
PHC1_HUMAN	PHC1	physical	23080069
PIAS1_HUMAN	PIAS1	physical	23080069
NEB2_HUMAN	PPP1R9B	physical	23080069
ASPP1_HUMAN	PPP1R13B	physical	23080069
PP16A_HUMAN	PPP1R16A	physical	23080069
PPR18_HUMAN	PPP1R18	physical	23080069
PPR3C_HUMAN	PPP1R3C	physical	23080069
PP1R8_HUMAN	PPP1R8	physical	23080069
LARGN_HUMAN	PRR16	physical	23080069
RIF1_HUMAN	RIF1	physical	23080069
RL7_HUMAN	RPL7	physical	23080069
RPRD2_HUMAN	RPRD2	physical	23080069
RRP1B_HUMAN	RRP1B	physical	23080069
SH3R2_HUMAN	SH3RF2	physical	23080069
SHAN3_HUMAN	SHANK3	physical	23080069
STAM1_HUMAN	STAM	physical	23080069
STAU1_HUMAN	STAU1	physical	23080069
TACC2_HUMAN	TACC2	physical	23080069
TEFM_HUMAN	TEFM	physical	23080069
TOIP1_HUMAN	TOR1AIP1	physical	23080069
ASPP2_HUMAN	TP53BP2	physical	23080069
TPRN_HUMAN	TPRN	physical	23080069
WBP11_HUMAN	WBP11	physical	23080069
YLPM1_HUMAN	YLPM1	physical	23080069
ZDBF2_HUMAN	ZDBF2	physical	23080069
ZN318_HUMAN	ZNF318	physical	23080069
ZN667_HUMAN	ZNF667	physical	23080069
MDM4_HUMAN	MDM4	physical	23277204
RAF1_HUMAN	RAF1	physical	12374792
TPRN_HUMAN	TPRN	physical	21382349
PPR18_HUMAN	PPP1R18	physical	21382349
LMTK2_HUMAN	LMTK2	physical	21382349
NEK2_HUMAN	NEK2	physical	21382349
ASPP2_HUMAN	TP53BP2	physical	21382349
ASPP1_HUMAN	PPP1R13B	physical	21382349
PP1R8_HUMAN	PPP1R8	physical	21382349
RIF1_HUMAN	RIF1	physical	21382349
ANR42_HUMAN	ANKRD42	physical	21382349
YLPM1_HUMAN	YLPM1	physical	21382349
MTNB_HUMAN	APIP	physical	21382349
ASH2L_HUMAN	ASH2L	physical	21382349
CSRN1_HUMAN	CSRNP1	physical	21382349
C1QA_HUMAN	C1QA	physical	21382349
CSN5_HUMAN	COPS5	physical	21382349
CATL1_HUMAN	CTSL	physical	21382349
CYFP1_HUMAN	CYFIP1	physical	21382349
DACT1_HUMAN	DACT1	physical	21382349
DYRK4_HUMAN	DYRK4	physical	21382349
GLB1L_HUMAN	GLB1L	physical	21382349
MAAI_HUMAN	GSTZ1	physical	21382349
KC1A_HUMAN	CSNK1A1	physical	21382349
JAK2_HUMAN	JAK2	physical	21382349
KDM4D_HUMAN	KDM4D	physical	21382349
M4K4_HUMAN	MAP4K4	physical	21382349
NMT2_HUMAN	NMT2	physical	21382349
NRBP_HUMAN	NRBP1	physical	21382349
RANB9_HUMAN	RANBP9	physical	21382349
RIR1_HUMAN	RRM1	physical	21382349
SGCE_HUMAN	SGCE	physical	21382349
EST1A_HUMAN	SMG6	physical	21382349
TC1D4_HUMAN	TCTEX1D4	physical	21382349
T120A_HUMAN	TMEM120A	physical	21382349
TOPB1_HUMAN	TOPBP1	physical	21382349
TRA2A_HUMAN	TRA2A	physical	21382349
RPA43_HUMAN	TWISTNB	physical	21382349
TEX36_HUMAN	TEX36	physical	21382349
VSTM4_HUMAN	VSTM4	physical	21382349
PPR32_HUMAN	PPP1R32	physical	21382349
CK074_HUMAN	C11orf74	physical	21382349
CO059_HUMAN	C15orf59	physical	21382349
ENKD1_HUMAN	ENKD1	physical	21382349
CNST_HUMAN	CNST	physical	21382349
SPC1L_HUMAN	SPATC1L	physical	21382349
PPR35_HUMAN	PPP1R35	physical	21382349
CI050_HUMAN	C9orf50	physical	21382349
ZNF24_HUMAN	ZNF24	physical	21382349
KRCC1_HUMAN	KRCC1	physical	21382349
TENS1_HUMAN	TNS1	physical	21382349
RN19B_HUMAN	RNF19B	physical	21382349
IPP2_HUMAN	PPP1R2	physical	21382349
D39U1_HUMAN	SDR39U1	physical	21382349
SH3R2_HUMAN	SH3RF2	physical	21382349
SPOC1_HUMAN	SPOCD1	physical	21382349
STAR9_HUMAN	STARD9	physical	21382349
TBC19_HUMAN	TBC1D19	physical	21382349
HSP72_HUMAN	HSPA2	physical	21382349
HSP7C_HUMAN	HSPA8	physical	21382349
TBB5_HUMAN	TUBB	physical	21382349
ATPB_HUMAN	ATP5B	physical	21382349
ACTG_HUMAN	ACTG1	physical	21382349
TCPB_HUMAN	CCT2	physical	21382349
GSTM5_HUMAN	GSTM5	physical	21382349
SFRP1_HUMAN	SFRP1	physical	21382349
RMP_HUMAN	URI1	physical	21397856
ASPP2_HUMAN	TP53BP2	physical	21988832
GBP1_HUMAN	GBP1	physical	22863883
SMD2_HUMAN	SNRPD2	physical	22863883
NEMO_HUMAN	IKBKG	physical	24586659
TRAF3_HUMAN	TRAF3	physical	24586659
TRAF6_HUMAN	TRAF6	physical	24586659
ASPP2_HUMAN	TP53BP2	physical	25416956
ZFYV9_HUMAN	ZFYVE9	physical	25416956
CD2B2_HUMAN	CD2BP2	physical	25416956
CSRN1_HUMAN	CSRNP1	physical	25416956
CSRN2_HUMAN	CSRNP2	physical	25416956
RORG_HUMAN	RORC	physical	23555304
CLOCK_HUMAN	CLOCK	physical	23555304
ASPP1_HUMAN	PPP1R13B	physical	26186194
ASPP2_HUMAN	TP53BP2	physical	26186194
PP1R8_HUMAN	PPP1R8	physical	26186194
IPP2_HUMAN	PPP1R2	physical	26186194
IASPP_HUMAN	PPP1R13L	physical	26186194
RIF1_HUMAN	RIF1	physical	26186194
ZFYV9_HUMAN	ZFYVE9	physical	26186194
KNL1_HUMAN	CASC5	physical	26186194
KI67_HUMAN	MKI67	physical	26186194
RPC1_HUMAN	POLR3A	physical	26186194
NEB1_HUMAN	PPP1R9A	physical	26186194
NEB2_HUMAN	PPP1R9B	physical	26186194
GYS1_HUMAN	GYS1	physical	26186194
PPR18_HUMAN	PPP1R18	physical	26186194
RPAP3_HUMAN	RPAP3	physical	26186194
SCRIB_HUMAN	SCRIB	physical	26186194
LRRC1_HUMAN	LRRC1	physical	26186194
PLCL2_HUMAN	PLCL2	physical	26186194
KBP_HUMAN	KIAA1279	physical	26186194
YLPM1_HUMAN	YLPM1	physical	26186194
RPC5_HUMAN	POLR3E	physical	26186194
DSN1_HUMAN	DSN1	physical	26186194
PEAK1_HUMAN	PEAK1	physical	26186194
ZFY16_HUMAN	ZFYVE16	physical	26186194
ERBIN_HUMAN	ERBB2IP	physical	26186194
RRP1B_HUMAN	RRP1B	physical	26186194
E2AK4_HUMAN	EIF2AK4	physical	26186194
RMP_HUMAN	URI1	physical	26186194
PDRG1_HUMAN	PDRG1	physical	26186194
SHOC2_HUMAN	SHOC2	physical	26186194
LMTK2_HUMAN	LMTK2	physical	26186194
NU153_HUMAN	NUP153	physical	26186194
PP1A_HUMAN	PPP1CA	physical	26186194
CDCA2_HUMAN	CDCA2	physical	26186194
KI18A_HUMAN	KIF18A	physical	26186194
KCD20_HUMAN	KCTD20	physical	26186194
TANC2_HUMAN	TANC2	physical	26186194
RPAP2_HUMAN	RPAP2	physical	26186194
SNCAP_HUMAN	SNCAIP	physical	26186194
NDC80_HUMAN	NDC80	physical	26186194
WBP11_HUMAN	WBP11	physical	26186194
CC85C_HUMAN	CCDC85C	physical	26186194
NUF2_HUMAN	NUF2	physical	26186194
PP1RA_HUMAN	PPP1R10	physical	26186194
TPRN_HUMAN	TPRN	physical	26186194
CSRN2_HUMAN	CSRNP2	physical	26186194
RASF8_HUMAN	RASSF8	physical	26186194
CNST_HUMAN	CNST	physical	26186194
LENG8_HUMAN	LENG8	physical	26186194
PP1RB_HUMAN	PPP1R11	physical	26186194
CC85B_HUMAN	CCDC85B	physical	26186194
CT027_HUMAN	C20orf27	physical	26186194
PHAR4_HUMAN	PHACTR4	physical	26186194
RPC2_HUMAN	POLR3B	physical	26186194
UXT_HUMAN	UXT	physical	26186194
PPR3F_HUMAN	PPP1R3F	physical	26186194
RASF7_HUMAN	RASSF7	physical	26186194
PPR3D_HUMAN	PPP1R3D	physical	26186194
IPP2_HUMAN	PPP1R2	physical	26344197
PP1R7_HUMAN	PPP1R7	physical	26344197
DPYL2_HUMAN	DPYSL2	physical	17683050
ACTG_HUMAN	ACTG1	physical	26496610
AP2A1_HUMAN	AP2A1	physical	26496610
CALL3_HUMAN	CALML3	physical	26496610
CAPZB_HUMAN	CAPZB	physical	26496610
CLIC1_HUMAN	CLIC1	physical	26496610
CBPM_HUMAN	CPM	physical	26496610
DDX3X_HUMAN	DDX3X	physical	26496610
FLII_HUMAN	FLII	physical	26496610
ROA2_HUMAN	HNRNPA2B1	physical	26496610
HNRH3_HUMAN	HNRNPH3	physical	26496610
ILF3_HUMAN	ILF3	physical	26496610
MYO1B_HUMAN	MYO1B	physical	26496610
PFD2_HUMAN	PFDN2	physical	26496610
PP1A_HUMAN	PPP1CA	physical	26496610
IPP2_HUMAN	PPP1R2	physical	26496610
PP1R8_HUMAN	PPP1R8	physical	26496610
PP1RA_HUMAN	PPP1R10	physical	26496610
SVIL_HUMAN	SVIL	physical	26496610
TPM3_HUMAN	TPM3	physical	26496610
TPM4_HUMAN	TPM4	physical	26496610
RMP_HUMAN	URI1	physical	26496610
ABC3B_HUMAN	APOBEC3B	physical	26496610
SAFB2_HUMAN	SAFB2	physical	26496610
LMTK2_HUMAN	LMTK2	physical	26496610
COR1C_HUMAN	CORO1C	physical	26496610
RAI14_HUMAN	RAI14	physical	26496610
RBMX_HUMAN	RBMX	physical	26496610
ZN638_HUMAN	ZNF638	physical	26496610
PNMA3_HUMAN	PNMA3	physical	26496610
LIMA1_HUMAN	LIMA1	physical	26496610
PPHLN_HUMAN	PPHLN1	physical	26496610
PIHD1_HUMAN	PIH1D1	physical	26496610
RIF1_HUMAN	RIF1	physical	26496610
YLPM1_HUMAN	YLPM1	physical	26496610
NCOA5_HUMAN	NCOA5	physical	26496610
INF2_HUMAN	INF2	physical	26496610
PDRG1_HUMAN	PDRG1	physical	26496610
NEB2_HUMAN	PPP1R9B	physical	26496610
WDR92_HUMAN	WDR92	physical	26496610
ZN326_HUMAN	ZNF326	physical	26496610
RB12B_HUMAN	RBM12B	physical	26496610
RMXL1_HUMAN	RBMXL1	physical	26496610
KNL1_HUMAN	CASC5	physical	27880917
CC85C_HUMAN	CCDC85C	physical	27880917
CD2B2_HUMAN	CD2BP2	physical	27880917
CDCA2_HUMAN	CDCA2	physical	27880917
E2AK4_HUMAN	EIF2AK4	physical	27880917
ERBIN_HUMAN	ERBB2IP	physical	27880917
GSK3A_HUMAN	GSK3A	physical	27880917
GSK3B_HUMAN	GSK3B	physical	27880917
DHB3_HUMAN	HSD17B3	physical	27880917
LRRC1_HUMAN	LRRC1	physical	27880917
KI67_HUMAN	MKI67	physical	27880917
PEAK1_HUMAN	PEAK1	physical	27880917
PFD6_HUMAN	PFDN6	physical	27880917
PLCL2_HUMAN	PLCL2	physical	27880917
RPAB1_HUMAN	POLR2E	physical	27880917
PP1RA_HUMAN	PPP1R10	physical	27880917
PP1RB_HUMAN	PPP1R11	physical	27880917
ASPP1_HUMAN	PPP1R13B	physical	27880917
IASPP_HUMAN	PPP1R13L	physical	27880917
PPR18_HUMAN	PPP1R18	physical	27880917
IPP2_HUMAN	PPP1R2	physical	27880917
PP1R7_HUMAN	PPP1R7	physical	27880917
PP1R8_HUMAN	PPP1R8	physical	27880917
NEB1_HUMAN	PPP1R9A	physical	27880917
NEB2_HUMAN	PPP1R9B	physical	27880917
PQBP1_HUMAN	PQBP1	physical	27880917
PSME1_HUMAN	PSME1	physical	27880917
RIF1_HUMAN	RIF1	physical	27880917
RL13_HUMAN	RPL13	physical	27880917
RRP1B_HUMAN	RRP1B	physical	27880917
SCRIB_HUMAN	SCRIB	physical	27880917
SHOC2_HUMAN	SHOC2	physical	27880917
ASPP2_HUMAN	TP53BP2	physical	27880917
TPRN_HUMAN	TPRN	physical	27880917
UXT_HUMAN	UXT	physical	27880917
WBP11_HUMAN	WBP11	physical	27880917
WDR82_HUMAN	WDR82	physical	27880917
YLPM1_HUMAN	YLPM1	physical	27880917
ZFY16_HUMAN	ZFYVE16	physical	27880917
ZFYV9_HUMAN	ZFYVE9	physical	27880917
TPRN_HUMAN	TPRN	physical	28514442
PPR18_HUMAN	PPP1R18	physical	28514442
ZFYV9_HUMAN	ZFYVE9	physical	28514442
PP1R8_HUMAN	PPP1R8	physical	28514442
KI18A_HUMAN	KIF18A	physical	28514442
CDCA2_HUMAN	CDCA2	physical	28514442
SHOC2_HUMAN	SHOC2	physical	28514442
NEB1_HUMAN	PPP1R9A	physical	28514442
LMTK2_HUMAN	LMTK2	physical	28514442
ZFY16_HUMAN	ZFYVE16	physical	28514442
CNST_HUMAN	CNST	physical	28514442
TANC2_HUMAN	TANC2	physical	28514442
IPP2_HUMAN	PPP1R2	physical	28514442
PP1RA_HUMAN	PPP1R10	physical	28514442
E2AK4_HUMAN	EIF2AK4	physical	28514442
ASPP1_HUMAN	PPP1R13B	physical	28514442
PEAK1_HUMAN	PEAK1	physical	28514442
PPR3F_HUMAN	PPP1R3F	physical	28514442
PP1RB_HUMAN	PPP1R11	physical	28514442
PLCL2_HUMAN	PLCL2	physical	28514442
ASPP2_HUMAN	TP53BP2	physical	28514442
ERBIN_HUMAN	ERBB2IP	physical	28514442
RASF7_HUMAN	RASSF7	physical	28514442
IASPP_HUMAN	PPP1R13L	physical	28514442
KCD20_HUMAN	KCTD20	physical	28514442
KNL1_HUMAN	CASC5	physical	28514442
YLPM1_HUMAN	YLPM1	physical	28514442
SCRIB_HUMAN	SCRIB	physical	28514442
WBP11_HUMAN	WBP11	physical	28514442
RASF8_HUMAN	RASSF8	physical	28514442
PP1A_HUMAN	PPP1CA	physical	28514442
LENG8_HUMAN	LENG8	physical	28514442
KBP_HUMAN	KIAA1279	physical	28514442
KI67_HUMAN	MKI67	physical	28514442
CC85C_HUMAN	CCDC85C	physical	28514442
CT027_HUMAN	C20orf27	physical	28514442
PHAR4_HUMAN	PHACTR4	physical	28514442
CC85B_HUMAN	CCDC85B	physical	28514442
NDC80_HUMAN	NDC80	physical	28514442
RIF1_HUMAN	RIF1	physical	28514442
RPC1_HUMAN	POLR3A	physical	28514442
RMP_HUMAN	URI1	physical	28514442
NEB2_HUMAN	PPP1R9B	physical	28514442
DSN1_HUMAN	DSN1	physical	28514442
LRRC1_HUMAN	LRRC1	physical	28514442
CBARP_HUMAN	C19orf26	physical	28514442
RPAP3_HUMAN	RPAP3	physical	28514442
GYS1_HUMAN	GYS1	physical	28514442
RPC5_HUMAN	POLR3E	physical	28514442
RRP1B_HUMAN	RRP1B	physical	28514442
NUF2_HUMAN	NUF2	physical	28514442
RPC2_HUMAN	POLR3B	physical	28514442
PDRG1_HUMAN	PDRG1	physical	28514442
RPAP2_HUMAN	RPAP2	physical	28514442
CSRN2_HUMAN	CSRNP2	physical	28514442
NU153_HUMAN	NUP153	physical	28514442
SNCAP_HUMAN	SNCAIP	physical	28514442
PP1B_HUMAN	PPP1CB	physical	28514442
SFRP2_HUMAN	SFRP2	physical	17123353
SFRP1_HUMAN	SFRP1	physical	17123353
SFRP5_HUMAN	SFRP5	physical	17123353
PP1R7_HUMAN	PPP1R7	physical	27173435
PP1A_HUMAN	PPP1CA	physical	27173435
2A5G_HUMAN	PPP2R5C	physical	25487150

Drug and Disease Associations

Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of PP1G_HUMAN

Related Literatures of Post-Translational Modification

Acetylation
Reference	PubMed
"Lys-N and trypsin cover complementary parts of the phosphoproteome ina refined SCX-based approach."; Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,Mohammed S.; Anal. Chem. 81:4493-4501(2009). Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2, AND MASS SPECTROMETRY.	19413330 [Abstract]
"Lysine acetylation targets protein complexes and co-regulates majorcellular functions."; Choudhary C., Kumar C., Gnad F., Nielsen M.L., Rehman M., Walther T.,Olsen J.V., Mann M.; Science 325:834-840(2009). Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-147, AND MASS SPECTROMETRY.	19608861 [Abstract]
Phosphorylation
Reference	PubMed
"A quantitative atlas of mitotic phosphorylation."; Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,Elledge S.J., Gygi S.P.; Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-307, AND MASSSPECTROMETRY.	18669648 [Abstract]