dbPTM

RAI14_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	RAI14_HUMAN
UniProt AC	Q9P0K7
Protein Name	Ankycorbin
Gene Name	RAI14
Organism	Homo sapiens (Human).
Sequence Length	980
Subcellular Localization	Cytoplasm, cell cortex . Cytoplasm, cytoskeleton . Cell junction . Nucleus . Associated with the cortical actin cytoskeleton structures in terminal web and cell-cell adhesion sites and stress fibers (By similarity). Highly expressed at the ectoplasmi
Protein Description	Plays a role in actin regulation at the ectoplasmic specialization, a type of cell junction specific to testis. Important for establishment of sperm polarity and normal spermatid adhesion. May also promote integrity of Sertoli cell tight junctions at the blood-testis barrier..
Protein Sequence	MKSLKAKFRKSDTNEWNKNDDRLLQAVENGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVDSSGKTALHYAAAQGCLQAVQILCEHKSPINLKDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLACEIGSSNAVEALIKKGADLNLVDSLGYNALHYSKLSENAGIQSLLLSKISQDADLKTPTKPKQHDQVSKISSERSGTPKKRKAPPPPISPTQLSDVSSPRSITSTPLSGKESVFFAEPPFKAEISSIRENKDRLSDSTTGADSLLDISSEADQQDLLSLLQAKVASLTLHNKELQDKLQAKSPKEAEADLSFDSYHSTQTDLGPSLGKPGETSPPDSKSSPSVLIHSLGKSTTDNDVRIQQLQEILQDLQKRLESSEAERKQLQVELQSRRAELVCLNNTEISENSSDLSQKLKETQSKYEEAMKEVLSVQKQMKLGLVSPESMDNYSHFHELRVTEEEINVLKQDLQNALEESERNKEKVRELEEKLVEREKGTVIKPPVEEYEEMKSSYCSVIENMNKEKAFLFEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAELEDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQIRSEVSQVKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYAESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQLSYSTSSSKRQSQQLEALQQQVKQLQNQLAECKKQHQEVISVYRMHLLYAVQGQMDEDVQKVLKQILTMCKNQSQKK

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
1	Acetylation	-------MKSLKAKF -------CCCHHHHH	6.33	22814378
11	Phosphorylation	LKAKFRKSDTNEWNK HHHHHCCCCCCCCCC	45.47	25159151
13	Phosphorylation	AKFRKSDTNEWNKND HHHCCCCCCCCCCCC	41.97	21815630
33	Ubiquitination	AVENGDAEKVASLLG HHHCCCHHHHHHHHC	53.45	33845483
37	Phosphorylation	GDAEKVASLLGKKGA CCHHHHHHHHCCCCC	27.41	30266825
40 (in isoform 2)	Phosphorylation	-	34.62	27251275
41	Malonylation	KVASLLGKKGASATK HHHHHHCCCCCCCCC	48.26	26320211
41	Ubiquitination	KVASLLGKKGASATK HHHHHHCCCCCCCCC	48.26	33845483
44	Ubiquitination	SLLGKKGASATKHDS HHHCCCCCCCCCCCC	12.60	33845483
45	Phosphorylation	LLGKKGASATKHDSE HHCCCCCCCCCCCCC	45.18	20068231
47	Phosphorylation	GKKGASATKHDSEGK CCCCCCCCCCCCCCC	26.81	20068231
47	Ubiquitination	GKKGASATKHDSEGK CCCCCCCCCCCCCCC	26.81	27667366
101	Ubiquitination	AKNSHHECIRKLLQS HCCCHHHHHHHHHHC	2.95	32015554
109	Malonylation	IRKLLQSKCPAESVD HHHHHHCCCCHHHCC	31.14	26320211
109	Ubiquitination	IRKLLQSKCPAESVD HHHHHHCCCCHHHCC	31.14	32015554
112	Ubiquitination	LLQSKCPAESVDSSG HHHCCCCHHHCCCCC	31.03	32015554
143	Phosphorylation	QILCEHKSPINLKDL HHHHHCCCCCCHHHC	32.68	24719451
146 (in isoform 2)	Phosphorylation	-	44.41	24719451
187	Phosphorylation	SRNKSGRTALMLACE CCCCCCCCHHHHHHH	27.89	21406692
190 (in isoform 2)	Phosphorylation	-	1.75	21406692
193	Glutathionylation	RTALMLACEIGSSNA CCHHHHHHHHCCCHH	3.26	22555962
197	Phosphorylation	MLACEIGSSNAVEAL HHHHHHCCCHHHHHH	26.53	21406692
198	Phosphorylation	LACEIGSSNAVEALI HHHHHCCCHHHHHHH	24.48	21406692
216	Phosphorylation	ADLNLVDSLGYNALH CCCCCHHHCCCCHHH	19.06	29978859
218	Ubiquitination	LNLVDSLGYNALHYS CCCHHHCCCCHHHHH	20.01	32015554
219	Phosphorylation	NLVDSLGYNALHYSK CCHHHCCCCHHHHHH	11.53	29978859
222 (in isoform 2)	Phosphorylation	-	3.29	27642862
224	Phosphorylation	LGYNALHYSKLSENA CCCCHHHHHHCCCCC	14.35	29978859
225	Phosphorylation	GYNALHYSKLSENAG CCCHHHHHHCCCCCC	19.17	29978859
226	Ubiquitination	YNALHYSKLSENAGI CCHHHHHHCCCCCCH	49.19	32015554
228	Phosphorylation	ALHYSKLSENAGIQS HHHHHHCCCCCCHHH	32.32	23828894
228 (in isoform 2)	Phosphorylation	-	32.32	27642862
229	Ubiquitination	LHYSKLSENAGIQSL HHHHHCCCCCCHHHH	62.63	32015554
235	Phosphorylation	SENAGIQSLLLSKIS CCCCCHHHHHHHHHC	21.04	27050516
239	Phosphorylation	GIQSLLLSKISQDAD CHHHHHHHHHCCCCC	28.10	23828894
240	Ubiquitination	IQSLLLSKISQDADL HHHHHHHHHCCCCCC	46.47	33845483
241	Phosphorylation	QSLLLSKISQDADLK HHHHHHHHCCCCCCC	3.93	32645325
242	Phosphorylation	SLLLSKISQDADLKT HHHHHHHCCCCCCCC	26.24	23403867
248	Ubiquitination	ISQDADLKTPTKPKQ HCCCCCCCCCCCCCC	53.67	33845483
249	Phosphorylation	SQDADLKTPTKPKQH CCCCCCCCCCCCCCC	43.41	22167270
249 (in isoform 4)	Phosphorylation	-	43.41	24275569
251	Phosphorylation	DADLKTPTKPKQHDQ CCCCCCCCCCCCCHH	66.27	22167270
251	Ubiquitination	DADLKTPTKPKQHDQ CCCCCCCCCCCCCHH	66.27	33845483
251 (in isoform 4)	Phosphorylation	-	66.27	24275569
252	Phosphorylation	ADLKTPTKPKQHDQV CCCCCCCCCCCCHHH	51.96	32645325
252 (in isoform 2)	Phosphorylation	-	51.96	24719451
257 (in isoform 4)	Phosphorylation	-	48.35	24719451
260	Phosphorylation	PKQHDQVSKISSERS CCCCHHHHHHCCCCC	20.73	20068231
260 (in isoform 4)	Phosphorylation	-	20.73	25159151
261	Phosphorylation	KQHDQVSKISSERSG CCCHHHHHHCCCCCC	47.99	32142685
261 (in isoform 4)	Phosphorylation	-	47.99	24719451
263	Phosphorylation	HDQVSKISSERSGTP CHHHHHHCCCCCCCC	29.86	29496963
264	Phosphorylation	DQVSKISSERSGTPK HHHHHHCCCCCCCCC	40.27	20068231
264 (in isoform 4)	Phosphorylation	-	40.27	25159151
265 (in isoform 3)	Ubiquitination	-	44.04	21890473
266 (in isoform 2)	Phosphorylation	-	42.19	24719451
266 (in isoform 4)	Phosphorylation	-	42.19	29743597
267	Phosphorylation	SKISSERSGTPKKRK HHHCCCCCCCCCCCC	42.86	29514088
267 (in isoform 3)	Ubiquitination	-	42.86	21890473
267 (in isoform 4)	Phosphorylation	-	42.86	25159151
268 (in isoform 4)	Phosphorylation	-	52.86	25159151
269	Phosphorylation	ISSERSGTPKKRKAP HCCCCCCCCCCCCCC	32.93	28985074
271	Phosphorylation	SERSGTPKKRKAPPP CCCCCCCCCCCCCCC	66.11	32142685
272	Ubiquitination	ERSGTPKKRKAPPPP CCCCCCCCCCCCCCC	61.40	21906983
272 (in isoform 1)	Ubiquitination	-	61.40	21890473
273	Phosphorylation	RSGTPKKRKAPPPPI CCCCCCCCCCCCCCC	46.63	32142685
273	Ubiquitination	RSGTPKKRKAPPPPI CCCCCCCCCCCCCCC	46.63	32015554
274	Ubiquitination	SGTPKKRKAPPPPIS CCCCCCCCCCCCCCC	74.30	21906983
274 (in isoform 1)	Ubiquitination	-	74.30	21890473
275 (in isoform 2)	Ubiquitination	-	26.34	21890473
277 (in isoform 2)	Ubiquitination	-	52.76	21890473
281	Phosphorylation	KAPPPPISPTQLSDV CCCCCCCCCCCHHCC	27.89	30266825
282	Phosphorylation	APPPPISPTQLSDVS CCCCCCCCCCHHCCC	25.53	32142685
283	Phosphorylation	PPPPISPTQLSDVSS CCCCCCCCCHHCCCC	35.04	30266825
284	Phosphorylation	PPPISPTQLSDVSSP CCCCCCCCHHCCCCC	42.21	32142685
284	Ubiquitination	PPPISPTQLSDVSSP CCCCCCCCHHCCCCC	42.21	33845483
284 (in isoform 2)	Phosphorylation	-	42.21	24719451
285	Phosphorylation	PPISPTQLSDVSSPR CCCCCCCHHCCCCCC	5.34	32142685
286	Phosphorylation	PISPTQLSDVSSPRS CCCCCCHHCCCCCCC	26.58	30266825
289	Phosphorylation	PTQLSDVSSPRSITS CCCHHCCCCCCCCCC	39.35	30266825
289 (in isoform 2)	Phosphorylation	-	39.35	24719451
290	Phosphorylation	TQLSDVSSPRSITST CCHHCCCCCCCCCCC	24.95	30266825
292	Phosphorylation	LSDVSSPRSITSTPL HHCCCCCCCCCCCCC	42.51	32142685
292 (in isoform 2)	Phosphorylation	-	42.51	24719451
293	Phosphorylation	SDVSSPRSITSTPLS HCCCCCCCCCCCCCC	33.33	30266825
294	Ubiquitination	DVSSPRSITSTPLSG CCCCCCCCCCCCCCC	3.58	32015554
295	Phosphorylation	VSSPRSITSTPLSGK CCCCCCCCCCCCCCC	28.00	30266825
296	Phosphorylation	SSPRSITSTPLSGKE CCCCCCCCCCCCCCC	26.76	30266825
296 (in isoform 2)	Phosphorylation	-	26.76	24719451
297	Phosphorylation	SPRSITSTPLSGKES CCCCCCCCCCCCCCC	21.43	22167270
298 (in isoform 2)	Phosphorylation	-	25.05	21406692
299 (in isoform 2)	Phosphorylation	-	12.19	24719451
300	Phosphorylation	SITSTPLSGKESVFF CCCCCCCCCCCCEEE	49.36	25159151
300 (in isoform 2)	Phosphorylation	-	49.36	24719451
302	Ubiquitination	TSTPLSGKESVFFAE CCCCCCCCCCEEECC	43.36	32015554
303	Phosphorylation	STPLSGKESVFFAEP CCCCCCCCCEEECCC	56.51	32142685
303 (in isoform 2)	Phosphorylation	-	56.51	24719451
304	Phosphorylation	TPLSGKESVFFAEPP CCCCCCCCEEECCCC	27.92	22199227
305	Ubiquitination	PLSGKESVFFAEPPF CCCCCCCEEECCCCC	4.86	33845483
310	Phosphorylation	ESVFFAEPPFKAEIS CCEEECCCCCHHHHH	35.88	32142685
313	Ubiquitination	FFAEPPFKAEISSIR EECCCCCHHHHHHHH	51.38	33845483
316	Ubiquitination	EPPFKAEISSIRENK CCCCHHHHHHHHHCC	4.71	33845483
317	Phosphorylation	PPFKAEISSIRENKD CCCHHHHHHHHHCCC	15.95	30266825
318	Phosphorylation	PFKAEISSIRENKDR CCHHHHHHHHHCCCC	31.18	30266825
320 (in isoform 2)	Phosphorylation	-	43.30	21406692
321	Phosphorylation	AEISSIRENKDRLSD HHHHHHHHCCCCCCC	67.95	32142685
321 (in isoform 2)	Phosphorylation	-	67.95	24719451
323	Ubiquitination	ISSIRENKDRLSDST HHHHHHCCCCCCCCC	39.20	-
327	Phosphorylation	RENKDRLSDSTTGAD HHCCCCCCCCCCCHH	30.34	30278072
329	Phosphorylation	NKDRLSDSTTGADSL CCCCCCCCCCCHHHH	25.21	30278072
330	Phosphorylation	KDRLSDSTTGADSLL CCCCCCCCCCHHHHH	33.95	30278072
330 (in isoform 2)	Phosphorylation	-	33.95	24719451
331	Phosphorylation	DRLSDSTTGADSLLD CCCCCCCCCHHHHHC	34.03	30278072
332 (in isoform 2)	Phosphorylation	-	27.72	21406692
333 (in isoform 2)	Phosphorylation	-	10.92	21406692
335	Phosphorylation	DSTTGADSLLDISSE CCCCCHHHHHCCCCC	30.23	30278072
335	Ubiquitination	DSTTGADSLLDISSE CCCCCHHHHHCCCCC	30.23	33845483
336	Ubiquitination	STTGADSLLDISSEA CCCCHHHHHCCCCCC	5.25	27667366
338 (in isoform 2)	Phosphorylation	-	43.97	24719451
340	Phosphorylation	ADSLLDISSEADQQD HHHHHCCCCCCCHHH	23.07	25159151
340	Ubiquitination	ADSLLDISSEADQQD HHHHHCCCCCCCHHH	23.07	33845483
341	Phosphorylation	DSLLDISSEADQQDL HHHHCCCCCCCHHHH	36.82	25159151
343 (in isoform 2)	Phosphorylation	-	23.12	21406692
344	Ubiquitination	LDISSEADQQDLLSL HCCCCCCCHHHHHHH	42.49	27667366
344 (in isoform 2)	Phosphorylation	-	42.49	24719451
350	Phosphorylation	ADQQDLLSLLQAKVA CCHHHHHHHHHHHHH	34.04	28450419
350	Ubiquitination	ADQQDLLSLLQAKVA CCHHHHHHHHHHHHH	34.04	27667366
356	Ubiquitination	LSLLQAKVASLTLHN HHHHHHHHHHHHCCC	4.98	33845483
358	Phosphorylation	LLQAKVASLTLHNKE HHHHHHHHHHCCCHH	25.52	30266825
360	Phosphorylation	QAKVASLTLHNKELQ HHHHHHHHCCCHHHH	24.39	30266825
361	Ubiquitination	AKVASLTLHNKELQD HHHHHHHCCCHHHHH	5.20	33845483
361 (in isoform 2)	Phosphorylation	-	5.20	24719451
363 (in isoform 2)	Phosphorylation	-	42.48	24719451
364	Ubiquitination	ASLTLHNKELQDKLQ HHHHCCCHHHHHHHH	49.40	33845483
365	Ubiquitination	SLTLHNKELQDKLQA HHHCCCHHHHHHHHC	57.91	27667366
367	Ubiquitination	TLHNKELQDKLQAKS HCCCHHHHHHHHCCC	47.05	33845483
369	Ubiquitination	HNKELQDKLQAKSPK CCHHHHHHHHCCCHH	29.54	33845483
372	Ubiquitination	ELQDKLQAKSPKEAE HHHHHHHCCCHHHHH	25.40	33845483
373	Ubiquitination	LQDKLQAKSPKEAEA HHHHHHCCCHHHHHC	55.09	27667366
374	Phosphorylation	QDKLQAKSPKEAEAD HHHHHCCCHHHHHCC	44.19	20068231
375	Ubiquitination	DKLQAKSPKEAEADL HHHHCCCHHHHHCCC	37.49	27667366
376	Ubiquitination	KLQAKSPKEAEADLS HHHCCCHHHHHCCCC	76.33	27667366
379	Ubiquitination	AKSPKEAEADLSFDS CCCHHHHHCCCCCCC	43.75	27667366
382	Phosphorylation	PKEAEADLSFDSYHS HHHHHCCCCCCCCCC	7.67	32142685
383	Phosphorylation	KEAEADLSFDSYHST HHHHCCCCCCCCCCC	27.79	22199227
386	Phosphorylation	EADLSFDSYHSTQTD HCCCCCCCCCCCCCC	23.80	22199227
387	Phosphorylation	ADLSFDSYHSTQTDL CCCCCCCCCCCCCCC	11.13	30576142
389	Phosphorylation	LSFDSYHSTQTDLGP CCCCCCCCCCCCCCC	17.61	30576142
389 (in isoform 2)	Phosphorylation	-	17.61	27251275
390	Phosphorylation	SFDSYHSTQTDLGPS CCCCCCCCCCCCCCC	23.36	30576142
390 (in isoform 2)	Phosphorylation	-	23.36	27251275
392	Phosphorylation	DSYHSTQTDLGPSLG CCCCCCCCCCCCCCC	33.02	22199227
393 (in isoform 2)	Phosphorylation	-	39.55	27251275
397	Phosphorylation	TQTDLGPSLGKPGET CCCCCCCCCCCCCCC	48.21	22199227
403	Phosphorylation	PSLGKPGETSPPDSK CCCCCCCCCCCCCCC	55.42	32142685
404	Phosphorylation	SLGKPGETSPPDSKS CCCCCCCCCCCCCCC	53.07	29255136
405	Phosphorylation	LGKPGETSPPDSKSS CCCCCCCCCCCCCCC	30.08	29255136
407 (in isoform 2)	Phosphorylation	-	59.27	27251275
409	Phosphorylation	GETSPPDSKSSPSVL CCCCCCCCCCCCCEE	39.96	28857561
411	Phosphorylation	TSPPDSKSSPSVLIH CCCCCCCCCCCEEEE	51.97	22167270
412	Phosphorylation	SPPDSKSSPSVLIHS CCCCCCCCCCEEEEC	25.57	22167270
414	Phosphorylation	PDSKSSPSVLIHSLG CCCCCCCCEEEECCC	31.35	22167270
414	Ubiquitination	PDSKSSPSVLIHSLG CCCCCCCCEEEECCC	31.35	32015554
414 (in isoform 2)	Phosphorylation	-	31.35	24719451
415 (in isoform 2)	Phosphorylation	-	7.08	27251275
417 (in isoform 2)	Phosphorylation	-	1.62	21406692
419	Phosphorylation	SPSVLIHSLGKSTTD CCCEEEECCCCCCCC	31.65	28355574
422	Phosphorylation	VLIHSLGKSTTDNDV EEEECCCCCCCCCHH	50.34	32142685
422 (in isoform 2)	Phosphorylation	-	50.34	24719451
423	Phosphorylation	LIHSLGKSTTDNDVR EEECCCCCCCCCHHH	34.44	29514088
424	Phosphorylation	IHSLGKSTTDNDVRI EECCCCCCCCCHHHH	41.47	29514088
425	Phosphorylation	HSLGKSTTDNDVRIQ ECCCCCCCCCHHHHH	39.64	29514088
435	Ubiquitination	DVRIQQLQEILQDLQ HHHHHHHHHHHHHHH	31.20	32015554
443	Ubiquitination	EILQDLQKRLESSEA HHHHHHHHHHHCCHH	67.27	32015554
446	Ubiquitination	QDLQKRLESSEAERK HHHHHHHHCCHHHHH	57.14	32015554
447	Phosphorylation	DLQKRLESSEAERKQ HHHHHHHCCHHHHHH	37.76	25072903
448	Phosphorylation	LQKRLESSEAERKQL HHHHHHCCHHHHHHH	31.30	25072903
455	Ubiquitination	SEAERKQLQVELQSR CHHHHHHHHHHHHHH	7.45	32015554
461	Phosphorylation	QLQVELQSRRAELVC HHHHHHHHHCCEEEE	36.04	22210691
462	Ubiquitination	LQVELQSRRAELVCL HHHHHHHHCCEEEEE	28.94	33845483
470	Ubiquitination	RAELVCLNNTEISEN CCEEEEECCCCCCCC	48.53	21890473
472	Phosphorylation	ELVCLNNTEISENSS EEEEECCCCCCCCCC	33.35	28674419
475	Phosphorylation	CLNNTEISENSSDLS EECCCCCCCCCCHHH	25.21	22199227
476	Ubiquitination	LNNTEISENSSDLSQ ECCCCCCCCCCHHHH	67.79	32015554
478	Phosphorylation	NTEISENSSDLSQKL CCCCCCCCCHHHHHH	22.60	22199227
478	Ubiquitination	NTEISENSSDLSQKL CCCCCCCCCHHHHHH	22.60	21890473
479	Phosphorylation	TEISENSSDLSQKLK CCCCCCCCHHHHHHH	54.90	22199227
482	Phosphorylation	SENSSDLSQKLKETQ CCCCCHHHHHHHHHH	30.20	27251275
482 (in isoform 2)	Phosphorylation	-	30.20	27251275
483	Phosphorylation	ENSSDLSQKLKETQS CCCCHHHHHHHHHHH	63.50	32142685
483	Ubiquitination	ENSSDLSQKLKETQS CCCCHHHHHHHHHHH	63.50	33845483
484	Ubiquitination	NSSDLSQKLKETQSK CCCHHHHHHHHHHHH	59.14	21890473
485 (in isoform 2)	Phosphorylation	-	4.74	27251275
487	Ubiquitination	DLSQKLKETQSKYEE HHHHHHHHHHHHHHH	63.62	32015554
491	Ubiquitination	KLKETQSKYEEAMKE HHHHHHHHHHHHHHH	47.03	33845483
494	Ubiquitination	ETQSKYEEAMKEVLS HHHHHHHHHHHHHHH	51.48	33845483
495 (in isoform 2)	Phosphorylation	-	11.47	27642862
499	Ubiquitination	YEEAMKEVLSVQKQM HHHHHHHHHHHHHHH	3.94	21890473
500 (in isoform 3)	Ubiquitination	-	4.32	21890473
504	Phosphorylation	KEVLSVQKQMKLGLV HHHHHHHHHHHCCCC	50.64	32142685
507	Ubiquitination	LSVQKQMKLGLVSPE HHHHHHHHCCCCCHH	36.59	32015554
507 (in isoform 1)	Ubiquitination	-	36.59	21890473
509	Ubiquitination	VQKQMKLGLVSPESM HHHHHHCCCCCHHHC	20.65	21890473
510	Ubiquitination	QKQMKLGLVSPESMD HHHHHCCCCCHHHCC	5.09	21890473
510 (in isoform 2)	Ubiquitination	-	5.09	21890473
512	Phosphorylation	QMKLGLVSPESMDNY HHHCCCCCHHHCCCC	28.17	30266825
513	Ubiquitination	MKLGLVSPESMDNYS HHCCCCCHHHCCCCC	30.15	21890473
515	Phosphorylation	LGLVSPESMDNYSHF CCCCCHHHCCCCCCC	34.52	30266825
515 (in isoform 2)	Phosphorylation	-	34.52	24719451
518 (in isoform 2)	Phosphorylation	-	31.40	27642862
519	Phosphorylation	SPESMDNYSHFHELR CHHHCCCCCCCHHHC	10.16	21712546
520	Phosphorylation	PESMDNYSHFHELRV HHHCCCCCCCHHHCC	26.40	24732914
522 (in isoform 2)	Phosphorylation	-	3.83	27642862
528	Ubiquitination	HFHELRVTEEEINVL CCHHHCCCHHHHHHH	31.11	32015554
536	Ubiquitination	EEEINVLKQDLQNAL HHHHHHHHHHHHHHH	37.17	32015554
539	Ubiquitination	INVLKQDLQNALEES HHHHHHHHHHHHHHH	3.81	32015554
557	Ubiquitination	KEKVRELEEKLVERE HHHHHHHHHHHHHHH	48.62	23503661
563	Ubiquitination	LEEKLVEREKGTVIK HHHHHHHHHCCCCCC	43.37	23503661
565	Ubiquitination	EKLVEREKGTVIKPP HHHHHHHCCCCCCCC	67.13	23503661
571	Ubiquitination	EKGTVIKPPVEEYEE HCCCCCCCCHHHHHH	27.35	23503661
576	Phosphorylation	IKPPVEEYEEMKSSY CCCCHHHHHHHHHHH	12.04	29978859
577	Ubiquitination	KPPVEEYEEMKSSYC CCCHHHHHHHHHHHH	55.70	23503661
579 (in isoform 2)	Phosphorylation	-	3.22	27642862
582	Phosphorylation	EYEEMKSSYCSVIEN HHHHHHHHHHHHHHH	25.33	-
583	Phosphorylation	YEEMKSSYCSVIENM HHHHHHHHHHHHHHC	8.88	22817900
585	Phosphorylation	EMKSSYCSVIENMNK HHHHHHHHHHHHCCH	20.21	28555341
586	Ubiquitination	MKSSYCSVIENMNKE HHHHHHHHHHHCCHH	5.93	23503661
586 (in isoform 2)	Phosphorylation	-	5.93	27642862
587	Ubiquitination	KSSYCSVIENMNKEK HHHHHHHHHHCCHHH	1.49	32015554
592	Ubiquitination	SVIENMNKEKAFLFE HHHHHCCHHHHHHHH	50.23	23503661
594	Ubiquitination	IENMNKEKAFLFEKY HHHCCHHHHHHHHHH	46.15	23503661
596	Ubiquitination	NMNKEKAFLFEKYQE HCCHHHHHHHHHHHH	13.71	23503661
597	Ubiquitination	MNKEKAFLFEKYQEA CCHHHHHHHHHHHHH	6.91	23503661
600	Ubiquitination	EKAFLFEKYQEAQEE HHHHHHHHHHHHHHH	44.92	23503661
601	Phosphorylation	KAFLFEKYQEAQEEI HHHHHHHHHHHHHHH	12.37	-
602	Ubiquitination	AFLFEKYQEAQEEIM HHHHHHHHHHHHHHH	51.09	23503661
603	Ubiquitination	FLFEKYQEAQEEIMK HHHHHHHHHHHHHHH	49.59	23503661
603 (in isoform 2)	Ubiquitination	-	49.59	-
606	Ubiquitination	EKYQEAQEEIMKLKD HHHHHHHHHHHHHHH	57.44	23503661
608	Ubiquitination	YQEAQEEIMKLKDTL HHHHHHHHHHHHHHH	2.65	32015554
616	Ubiquitination	MKLKDTLKSQMTQEA HHHHHHHHHHHHHHH	40.51	32015554
617	Phosphorylation	KLKDTLKSQMTQEAS HHHHHHHHHHHHHHH	28.44	27251275
619	Ubiquitination	KDTLKSQMTQEASDE HHHHHHHHHHHHHHH	5.58	32015554
620	Phosphorylation	DTLKSQMTQEASDEA HHHHHHHHHHHHHHH	18.67	29396449
624	Phosphorylation	SQMTQEASDEAEDMK HHHHHHHHHHHHHHH	34.92	25159151
638	Phosphorylation	KEAMNRMIDELNKQV HHHHHHHHHHHHHHH	3.17	32142685
646	Phosphorylation	DELNKQVSELSQLYK HHHHHHHHHHHHHHH	30.26	29449344
649	Phosphorylation	NKQVSELSQLYKEAQ HHHHHHHHHHHHHHH	17.68	28674419
652	Phosphorylation	VSELSQLYKEAQAEL HHHHHHHHHHHHHHH	10.11	29449344
659	Phosphorylation	YKEAQAELEDYRKRK HHHHHHHHHHHHHHC	7.32	32142685
667	Phosphorylation	EDYRKRKSLEDVTAE HHHHHHCCHHHHHHH	40.81	30266825
670	Phosphorylation	RKRKSLEDVTAEYIH HHHCCHHHHHHHHHH	48.65	32142685
670 (in isoform 2)	Phosphorylation	-	48.65	24719451
672	Phosphorylation	RKSLEDVTAEYIHKA HCCHHHHHHHHHHHH	26.54	23403867
675	Phosphorylation	LEDVTAEYIHKAEHE HHHHHHHHHHHHHHH	13.08	23403867
675 (in isoform 2)	Phosphorylation	-	13.08	27251275
688	Phosphorylation	HEKLMQLTNVSRAKA HHHHHHHHCCCHHHH	19.38	27174698
691	Phosphorylation	LMQLTNVSRAKAEDA HHHHHCCCHHHHHHH	28.70	27174698
694	Malonylation	LTNVSRAKAEDALSE HHCCCHHHHHHHHHH	51.72	26320211
779	Sulfoxidation	LLEEKAAMTDAMVPR HHHHHHHCCCCCCCH	4.10	30846556
780	Phosphorylation	LEEKAAMTDAMVPRS HHHHHHCCCCCCCHH	18.84	20068231
783	Sulfoxidation	KAAMTDAMVPRSSYE HHHCCCCCCCHHHHH	4.79	30846556
788	Phosphorylation	DAMVPRSSYEKLQSS CCCCCHHHHHHHHHH	38.29	20860994
789	Phosphorylation	AMVPRSSYEKLQSSL CCCCHHHHHHHHHHH	20.52	20860994
794	Phosphorylation	SSYEKLQSSLESEVS HHHHHHHHHHHHHHH	47.53	25850435
795	Phosphorylation	SYEKLQSSLESEVSV HHHHHHHHHHHHHHH	24.16	29507054
797 (in isoform 2)	Phosphorylation	-	46.96	24719451
798	Phosphorylation	KLQSSLESEVSVLAS HHHHHHHHHHHHHHH	48.90	21406692
801	Phosphorylation	SSLESEVSVLASKLK HHHHHHHHHHHHHHH	13.83	21406692
804 (in isoform 2)	Phosphorylation	-	11.49	21406692
805	Phosphorylation	SEVSVLASKLKESVK HHHHHHHHHHHHHHH	34.07	21406692
869	Phosphorylation	ELAEMKRYAESSSKL HHHHHHHHHHHHHHH	14.81	-
875	Ubiquitination	RYAESSSKLEEDKDK HHHHHHHHHHHHHHH	62.96	21890473
883	Ubiquitination	LEEDKDKKINEMSKE HHHHHHHHHHHHHHH	61.98	21890473
886	Phosphorylation	DKDKKINEMSKEVTK HHHHHHHHHHHHHHH	48.59	32142685
889	Ubiquitination	KKINEMSKEVTKLKE HHHHHHHHHHHHHHH	55.69	21890473
897	Ubiquitination	EVTKLKEALNSLSQL HHHHHHHHHHHHHHH	15.51	32015554
899	Ubiquitination	TKLKEALNSLSQLSY HHHHHHHHHHHHHHC	48.21	23503661
900	Ubiquitination	KLKEALNSLSQLSYS HHHHHHHHHHHHHCC	30.19	23503661
902	Phosphorylation	KEALNSLSQLSYSTS HHHHHHHHHHHCCCC	28.97	29759185
904	Ubiquitination	ALNSLSQLSYSTSSS HHHHHHHHHCCCCCC	4.69	21890473
905	Phosphorylation	LNSLSQLSYSTSSSK HHHHHHHHCCCCCCH	14.92	29759185
905 (in isoform 3)	Ubiquitination	-	14.92	21890473
906	Phosphorylation	NSLSQLSYSTSSSKR HHHHHHHCCCCCCHH	25.26	22817900
907	Phosphorylation	SLSQLSYSTSSSKRQ HHHHHHCCCCCCHHH	20.59	28348404
907	Ubiquitination	SLSQLSYSTSSSKRQ HHHHHHCCCCCCHHH	20.59	23503661
908	Phosphorylation	LSQLSYSTSSSKRQS HHHHHCCCCCCHHHH	25.13	27251275
908	Ubiquitination	LSQLSYSTSSSKRQS HHHHHCCCCCCHHHH	25.13	33845483
908 (in isoform 2)	Phosphorylation	-	25.13	27251275
909	Phosphorylation	SQLSYSTSSSKRQSQ HHHHCCCCCCHHHHH	27.03	29507054
910	Phosphorylation	QLSYSTSSSKRQSQQ HHHCCCCCCHHHHHH	39.71	28555341
910 (in isoform 2)	Phosphorylation	-	39.71	27251275
911	Phosphorylation	LSYSTSSSKRQSQQL HHCCCCCCHHHHHHH	31.46	-
912	Ubiquitination	SYSTSSSKRQSQQLE HCCCCCCHHHHHHHH	57.30	23000965
912 (in isoform 1)	Ubiquitination	-	57.30	21890473
913	Ubiquitination	YSTSSSKRQSQQLEA CCCCCCHHHHHHHHH	43.24	23503661
914	Ubiquitination	STSSSKRQSQQLEAL CCCCCHHHHHHHHHH	49.69	21890473
915	Phosphorylation	TSSSKRQSQQLEALQ CCCCHHHHHHHHHHH	24.75	30266825
915	Ubiquitination	TSSSKRQSQQLEALQ CCCCHHHHHHHHHHH	24.75	21890473
915 (in isoform 2)	Ubiquitination	-	24.75	21890473
918	Phosphorylation	SKRQSQQLEALQQQV CHHHHHHHHHHHHHH	3.01	32142685
918	Ubiquitination	SKRQSQQLEALQQQV CHHHHHHHHHHHHHH	3.01	21890473
918 (in isoform 2)	Phosphorylation	-	3.01	24719451
926	Ubiquitination	EALQQQVKQLQNQLA HHHHHHHHHHHHHHH	40.74	32015554
927	Ubiquitination	ALQQQVKQLQNQLAE HHHHHHHHHHHHHHH	49.80	23000965
928	Ubiquitination	LQQQVKQLQNQLAEC HHHHHHHHHHHHHHH	4.23	23503661
929	Ubiquitination	QQQVKQLQNQLAECK HHHHHHHHHHHHHHH	32.88	33845483
930	Ubiquitination	QQVKQLQNQLAECKK HHHHHHHHHHHHHHH	47.64	23000965
935	Ubiquitination	LQNQLAECKKQHQEV HHHHHHHHHHHHHHH	5.77	23000965
936	Acetylation	QNQLAECKKQHQEVI HHHHHHHHHHHHHHH	47.15	7610223
936	Ubiquitination	QNQLAECKKQHQEVI HHHHHHHHHHHHHHH	47.15	23503661
937	Ubiquitination	NQLAECKKQHQEVIS HHHHHHHHHHHHHHH	65.75	33845483
938	Ubiquitination	QLAECKKQHQEVISV HHHHHHHHHHHHHHH	29.05	23000965
939	Ubiquitination	LAECKKQHQEVISVY HHHHHHHHHHHHHHH	34.35	23503661
940	Ubiquitination	AECKKQHQEVISVYR HHHHHHHHHHHHHHH	44.13	33845483
940 (in isoform 2)	Ubiquitination	-	44.13	-
941	Ubiquitination	ECKKQHQEVISVYRM HHHHHHHHHHHHHHH	39.43	23000965
942	Ubiquitination	CKKQHQEVISVYRMH HHHHHHHHHHHHHHH	2.96	23503661
943	Ubiquitination	KKQHQEVISVYRMHL HHHHHHHHHHHHHHH	1.96	23503661
944	Ubiquitination	KQHQEVISVYRMHLL HHHHHHHHHHHHHHH	20.48	23000965
952	Phosphorylation	VYRMHLLYAVQGQMD HHHHHHHHHHCCCCC	15.87	26074081
956	Ubiquitination	HLLYAVQGQMDEDVQ HHHHHHCCCCCHHHH	20.41	23000965
959	Ubiquitination	YAVQGQMDEDVQKVL HHHCCCCCHHHHHHH	40.85	23000965
964	Ubiquitination	QMDEDVQKVLKQILT CCCHHHHHHHHHHHH	49.75	23000965
966	Ubiquitination	DEDVQKVLKQILTMC CHHHHHHHHHHHHHH	4.32	23000965
967	Ubiquitination	EDVQKVLKQILTMCK HHHHHHHHHHHHHHH	37.98	23000965
967 (in isoform 2)	Ubiquitination	-	37.98	-
969	Ubiquitination	VQKVLKQILTMCKNQ HHHHHHHHHHHHHCH	3.10	23000965
970	Ubiquitination	QKVLKQILTMCKNQS HHHHHHHHHHHHCHH	2.01	23000965
970 (in isoform 2)	Ubiquitination	-	2.01	-
971	Phosphorylation	KVLKQILTMCKNQSQ HHHHHHHHHHHCHHC	23.35	26074081
973	Ubiquitination	LKQILTMCKNQSQKK HHHHHHHHHCHHCCC	2.93	23000965
977	Phosphorylation	LTMCKNQSQKK---- HHHHHCHHCCC----	54.05	18669648

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of RAI14_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of RAI14_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of RAI14_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
TARA_HUMAN	TRIOBP	physical	26344197
FTM_HUMAN	RPGRIP1L	physical	27173435

Drug and Disease Associations

Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of RAI14_HUMAN

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Large-scale proteomics analysis of the human kinome."; Oppermann F.S., Gnad F., Olsen J.V., Hornberger R., Greff Z., Keri G.,Mann M., Daub H.; Mol. Cell. Proteomics 8:1751-1764(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-249; SER-260; SER-318AND SER-358, AND MASS SPECTROMETRY.	19369195 [Abstract]
"A quantitative atlas of mitotic phosphorylation."; Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,Elledge S.J., Gygi S.P.; Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-293, AND MASSSPECTROMETRY.	18669648 [Abstract]
"Kinase-selective enrichment enables quantitative phosphoproteomics ofthe kinome across the cell cycle."; Daub H., Olsen J.V., Bairlein M., Gnad F., Oppermann F.S., Korner R.,Greff Z., Keri G., Stemmann O., Mann M.; Mol. Cell 31:438-448(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-249 AND SER-358, ANDMASS SPECTROMETRY.	18691976 [Abstract]