PPR32_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: PPR32_HUMAN
• UniProt AC: Q7Z5V6
• Protein Name: Protein phosphatase 1 regulatory subunit 32
• Gene Name: PPP1R32
• Organism: Homo sapiens (Human).
• Sequence Length: 425
• Protein Sequence: MMGKLPLGVVSPYVKMSSGGYTDPLKFYATSYCTAYGREDFKPRVGSHVGTGYKSNFQPVVSCQASLEALDNPARGEQAQDHFQSVASQSYRPLEVPDGKHPLPWSMRQTSSGYGREKPSAGPPTKEVRKVHFDTQEHGPQAITGLEPREVPLLHQQQGQDPLERENFRHGPRFMTSEYNSKYLRDPLDQPDFLQKKSIGAKEGSGFTKQSHQSPIVFQPPSQALPGDPALLPGQSVTKSDFLPKTHLHGDEFLPVLARGSKRETAFSRGNERILNPRVPPPCPEPSSVSHQQFQPLHRMQQTNVALLGRETVGKKEPTGFSLNNPMYVRSPCDPDRDQRYLTTYNQGYFENIPKGLDQEGWTRGGIQPQMPGGYALSQPVSCMEATPNPMESLRHLHPHVGRTLTSADPFYQNTPHSSRCVAHS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
11	Phosphorylation	KLPLGVVSPYVKMSS CCCCCEECCEEEECC	14.22	23607784
13	Phosphorylation	PLGVVSPYVKMSSGG CCCEECCEEEECCCC	12.75	23607784
17	Phosphorylation	VSPYVKMSSGGYTDP ECCEEEECCCCCCCC	21.80	23607784
18	Phosphorylation	SPYVKMSSGGYTDPL CCEEEECCCCCCCCH	32.51	23607784
21	Phosphorylation	VKMSSGGYTDPLKFY EEECCCCCCCCHHHE	16.11	23607784
22	Phosphorylation	KMSSGGYTDPLKFYA EECCCCCCCCHHHEE	34.12	23607784
28	Phosphorylation	YTDPLKFYATSYCTA CCCCHHHEEEEHHCC	13.84	-
32	Phosphorylation	LKFYATSYCTAYGRE HHHEEEEHHCCCCCC	6.89	-
62	Phosphorylation	SNFQPVVSCQASLEA CCCEEEEEEHHHHHH	10.76	25693802
66	Phosphorylation	PVVSCQASLEALDNP EEEEEHHHHHHHHCC	10.81	25693802
100	Acetylation	PLEVPDGKHPLPWSM CCCCCCCCCCCCCCC	49.80	25038526
108	Methylation	HPLPWSMRQTSSGYG CCCCCCCCCCCCCCC	30.98	115372627
108	Dimethylation	HPLPWSMRQTSSGYG CCCCCCCCCCCCCCC	30.98	-
120	Phosphorylation	GYGREKPSAGPPTKE CCCCCCCCCCCCCCC	57.85	30177828
341	Phosphorylation	DPDRDQRYLTTYNQG CCCCCHHHCHHHCCC	11.63	24719451
344	Phosphorylation	RDQRYLTTYNQGYFE CCHHHCHHHCCCCHH	20.20	24719451
375	Phosphorylation	QPQMPGGYALSQPVS CCCCCCCEECCCCCC	15.41	24043423
378	Phosphorylation	MPGGYALSQPVSCME CCCCEECCCCCCCEE	25.02	24043423
382	Phosphorylation	YALSQPVSCMEATPN EECCCCCCCEECCCC	17.90	24043423
387	Phosphorylation	PVSCMEATPNPMESL CCCCEECCCCHHHHH	15.42	24043423
393	Phosphorylation	ATPNPMESLRHLHPH CCCCHHHHHHHHCCC	25.17	24043423

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of PPR32_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of PPR32_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of PPR32_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
A4_HUMAN	APP	physical	21832049
PP1G_HUMAN	PPP1CC	physical	21382349
UBR1_HUMAN	UBR1	physical	28514442
IDE_HUMAN	IDE	physical	28514442

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.