RPRD2_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RPRD2_HUMAN
• UniProt AC: Q5VT52
• Protein Name: Regulation of nuclear pre-mRNA domain-containing protein 2
• Gene Name: RPRD2
• Organism: Homo sapiens (Human).
• Sequence Length: 1461
• Protein Sequence: MAAGGGGGSSKASSSSASSAGALESSLDRKFQSVTNTMESIQGLSSWCIENKKHHSTIVYHWMKWLRRSAYPHRLNLFYLANDVIQNCKRKNAIIFRESFADVLPEAAALVKDPSVSKSVERIFKIWEDRNVYPEEMIVALREALSTTFKTQKQLKENLNKQPNKQWKKSQTSTNPKAALKSKIVAEFRSQALIEELLLYKRSEDQIELKEKQLSTMRVDVCSTETLKCLKDKTGGKKFSKEFEEASSKLEEFVNGLDKQVKNGPSLTEALENAGIFYEAQYKEVKVVANAYKTFANRVNNLKKKLDQLKSTLPDPEESPVPSPSMDAPSPTGSESPFQGMGGEESQSPTMESEKSATPEPVTDNRDVEDMELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATPPLPKPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNTGVSPASRPSPGTPTSPSNLTSGLKTPAPATTTSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQSVTGNPVPASEAASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEVSSTSASKASIGQSPGLPSTTFKLPSNSLGFTATHNTSPAAPPTEVTICQSSEVSKPKLESESTSPSLEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSESHPSDFQRGPTSTSIDNIDGTPVRDERSGTPTQDEMMDKPTSSSVDTMSLLSKIISPGSSTPSSTRSPPPGRDESYPRELSNSVSTYRPFGLGSESPYKQPSDGMERPSSLMDSSQEKFYPDTSFQEDEDYRDFEYSGPPPSAMMNLEKKPAKSILKSSKLSDTTEYQPILSSYSHRAQEFGVKSAFPPSVRALLDSSENCDRLSSSPGLFGAFSVRGNEPGSDRSPSPSKNDSFFTPDSNHNSLSQSTTGHLSLPQKQYPDSPHPVPHRSLFSPQNTLAAPTGHPPTSGVEKVLASTISTTSTIEFKNMLKNASRKPSDDKHFGQAPSKGTPSDGVSLSNLTQPSLTATDQQQQEEHYRIETRVSSSCLDLPDSTEEKGAPIETLGYHSASNRRMSGEPIQTVESIRVPGKGNRGHGREASRVGWFDLSTSGSSFDNGPSSASELASLGGGGSGGLTGFKTAPYKERAPQFQESVGSFRSNSFNSTFEHHLPPSPLEHGTPFQREPVGPSSAPPVPPKDHGGIFSRDAPTHLPSVDLSNPFTKEAALAHAAPPPPPGEHSGIPFPTPPPPPPPGEHSSSGGSGVPFSTPPPPPPPVDHSGVVPFPAPPLAEHGVAGAVAVFPKDHSSLLQGTLAEHFGVLPGPRDHGGPTQRDLNGPGLSRVRESLTLPSHSLEHLGPPHGGGGGGGSNSSSGPPLGPSHRDTISRSGIILRSPRPDFRPREPFLSRDPFHSLKRPRPPFARGPPFFAPKRPFFPPRY

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MAAGGGGGS ------CCCCCCCCC	26.56	25489052
9	Phosphorylation	AAGGGGGSSKASSSS CCCCCCCCCCCCCCC	31.75	28674151
10	Phosphorylation	AGGGGGSSKASSSSA CCCCCCCCCCCCCCC	35.20	28674151
13	Phosphorylation	GGGSSKASSSSASSA CCCCCCCCCCCCCHH	34.19	21406692
14	Phosphorylation	GGSSKASSSSASSAG CCCCCCCCCCCCHHH	32.92	21406692
15	Phosphorylation	GSSKASSSSASSAGA CCCCCCCCCCCHHHH	27.68	27050516
16	O-linked_Glycosylation	SSKASSSSASSAGAL CCCCCCCCCCHHHHH	33.83	OGP
16	Phosphorylation	SSKASSSSASSAGAL CCCCCCCCCCHHHHH	33.83	27251789
18	Phosphorylation	KASSSSASSAGALES CCCCCCCCHHHHHHH	23.75	21406692
19	Phosphorylation	ASSSSASSAGALESS CCCCCCCHHHHHHHH	30.36	25849741
25	Phosphorylation	SSAGALESSLDRKFQ CHHHHHHHHHHHHHH	36.73	21406692
26	Phosphorylation	SAGALESSLDRKFQS HHHHHHHHHHHHHHH	25.55	21406692
37	Phosphorylation	KFQSVTNTMESIQGL HHHHHHHHHHHHHHH	16.98	24275569
79	Phosphorylation	PHRLNLFYLANDVIQ CHHHHHHHHHHHHHH	14.20	22817900
89	Acetylation	NDVIQNCKRKNAIIF HHHHHHCHHCCCEEE	74.16	26051181
99	Phosphorylation	NAIIFRESFADVLPE CCEEEEHHHHHHHHH	22.83	-
112	Ubiquitination	PEAAALVKDPSVSKS HHHHHHCCCCCCCHH	65.85	29967540
115	Phosphorylation	AALVKDPSVSKSVER HHHCCCCCCCHHHHH	49.51	26091039
118	Ubiquitination	VKDPSVSKSVERIFK CCCCCCCHHHHHHHH	57.26	29967540
125	Ubiquitination	KSVERIFKIWEDRNV HHHHHHHHHHHCCCC	44.53	-
125	Ubiquitination	KSVERIFKIWEDRNV HHHHHHHHHHHCCCC	44.53	-
150	Ubiquitination	EALSTTFKTQKQLKE HHHHHHHHHHHHHHH	48.21	29967540
151	Ubiquitination	ALSTTFKTQKQLKEN HHHHHHHHHHHHHHH	36.49	29967540
157	Ubiquitination	KTQKQLKENLNKQPN HHHHHHHHHHHCCCC	75.45	21890473
161	Ubiquitination	QLKENLNKQPNKQWK HHHHHHHCCCCHHHH	71.01	30230243
170	Phosphorylation	PNKQWKKSQTSTNPK CCHHHHHHCCCCCHH	34.66	23403867
172	O-linked_Glycosylation	KQWKKSQTSTNPKAA HHHHHHCCCCCHHHH	44.61	20068230
172	Phosphorylation	KQWKKSQTSTNPKAA HHHHHHCCCCCHHHH	44.61	23403867
173	O-linked_Glycosylation	QWKKSQTSTNPKAAL HHHHHCCCCCHHHHH	20.67	20068230
173	Phosphorylation	QWKKSQTSTNPKAAL HHHHHCCCCCHHHHH	20.67	23403867
174	O-linked_Glycosylation	WKKSQTSTNPKAALK HHHHCCCCCHHHHHH	59.95	20068230
174	Phosphorylation	WKKSQTSTNPKAALK HHHHCCCCCHHHHHH	59.95	21601212
175	Ubiquitination	KKSQTSTNPKAALKS HHHCCCCCHHHHHHH	35.52	29967540
177	Ubiquitination	SQTSTNPKAALKSKI HCCCCCHHHHHHHHH	48.65	29967540
190	Phosphorylation	KIVAEFRSQALIEEL HHHHHHHHHHHHHHH	25.73	26552605
200	Phosphorylation	LIEELLLYKRSEDQI HHHHHHHHHCCHHHH	12.34	26552605
201	Ubiquitination	IEELLLYKRSEDQIE HHHHHHHHCCHHHHH	49.79	29967540
212	Ubiquitination	DQIELKEKQLSTMRV HHHHHHHHHHHCCEE	55.76	29967540
215	Ubiquitination	ELKEKQLSTMRVDVC HHHHHHHHCCEEEEC	20.05	29967540
223	Ubiquitination	TMRVDVCSTETLKCL CCEEEECCHHHHHHH	29.18	29967540
228	Acetylation	VCSTETLKCLKDKTG ECCHHHHHHHHCCCC	44.96	26051181
233	Ubiquitination	TLKCLKDKTGGKKFS HHHHHHCCCCCCCCH	47.70	29967540
236	Ubiquitination	CLKDKTGGKKFSKEF HHHCCCCCCCCHHHH	34.90	29967540
238	Ubiquitination	KDKTGGKKFSKEFEE HCCCCCCCCHHHHHH	59.13	29967540
240	Phosphorylation	KTGGKKFSKEFEEAS CCCCCCCHHHHHHHH	39.91	29759185
241	Ubiquitination	TGGKKFSKEFEEASS CCCCCCHHHHHHHHH	70.34	29967540
248	Phosphorylation	KEFEEASSKLEEFVN HHHHHHHHHHHHHHH	48.59	23917254
249	Acetylation	EFEEASSKLEEFVNG HHHHHHHHHHHHHHH	58.38	66725089
249	Ubiquitination	EFEEASSKLEEFVNG HHHHHHHHHHHHHHH	58.38	29967540
253	Ubiquitination	ASSKLEEFVNGLDKQ HHHHHHHHHHHHHHH	3.64	22505724
256 (in isoform 2)	Ubiquitination	-	29.92	21890473
257	Ubiquitination	LEEFVNGLDKQVKNG HHHHHHHHHHHHHCC	6.66	29967540
259	Ubiquitination	EFVNGLDKQVKNGPS HHHHHHHHHHHCCCC	63.13	29967540
260	Ubiquitination	FVNGLDKQVKNGPSL HHHHHHHHHHCCCCH	51.59	29967540
262	Ubiquitination	NGLDKQVKNGPSLTE HHHHHHHHCCCCHHH	54.41	29967540
267	Ubiquitination	QVKNGPSLTEALENA HHHCCCCHHHHHHHC	5.89	21890473
267	Ubiquitination	QVKNGPSLTEALENA HHHCCCCHHHHHHHC	5.89	21890473
267 (in isoform 3)	Ubiquitination	-	5.89	21890473
278	Phosphorylation	LENAGIFYEAQYKEV HHHCCCCEEEECCCH	14.40	17360941
283	Ubiquitination	IFYEAQYKEVKVVAN CCEEEECCCHHHHHH	43.90	29967540
286	Ubiquitination	EAQYKEVKVVANAYK EEECCCHHHHHHHHH	31.89	29967540
292	Phosphorylation	VKVVANAYKTFANRV HHHHHHHHHHHHHHH	15.46	-
293	Acetylation	KVVANAYKTFANRVN HHHHHHHHHHHHHHH	34.45	26051181
293	Ubiquitination	KVVANAYKTFANRVN HHHHHHHHHHHHHHH	34.45	22817900
293 (in isoform 1)	Ubiquitination	-	34.45	21890473
294	Phosphorylation	VVANAYKTFANRVNN HHHHHHHHHHHHHHH	18.46	-
298	Methylation	AYKTFANRVNNLKKK HHHHHHHHHHHHHHH	29.16	115492395
319	Phosphorylation	TLPDPEESPVPSPSM HCCCCCCCCCCCCCC	29.54	26074081
323	Phosphorylation	PEESPVPSPSMDAPS CCCCCCCCCCCCCCC	29.82	26074081
325	Phosphorylation	ESPVPSPSMDAPSPT CCCCCCCCCCCCCCC	33.36	26074081
330	Phosphorylation	SPSMDAPSPTGSESP CCCCCCCCCCCCCCC	36.49	20068231
332	Phosphorylation	SMDAPSPTGSESPFQ CCCCCCCCCCCCCCC	58.64	20068231
337 (in isoform 2)	Phosphorylation	-	22.87	19081932
348	Phosphorylation	MGGEESQSPTMESEK CCCCCCCCCCCCCCC	31.45	20166139
356	Phosphorylation	PTMESEKSATPEPVT CCCCCCCCCCCCCCC	33.07	29255136
358	Phosphorylation	MESEKSATPEPVTDN CCCCCCCCCCCCCCC	34.96	29255136
363	Ubiquitination	SATPEPVTDNRDVED CCCCCCCCCCCCHHH	37.97	-
363	Phosphorylation	SATPEPVTDNRDVED CCCCCCCCCCCCHHH	37.97	23927012
363	Ubiquitination	SATPEPVTDNRDVED CCCCCCCCCCCCHHH	37.97	22505724
374	Phosphorylation	DVEDMELSDVEDDGS CHHHCCCCCCCCCCC	26.72	29255136
381	Phosphorylation	SDVEDDGSKIIVEDR CCCCCCCCEEEEECC	27.89	30266825
389	Ubiquitination	KIIVEDRKEKPAEKS EEEEECCCCCCCHHC	80.54	22505724
396	O-linked_Glycosylation	KEKPAEKSAVSTSVP CCCCCHHCCCCCCCC	25.96	20068230
396	Phosphorylation	KEKPAEKSAVSTSVP CCCCCHHCCCCCCCC	25.96	28555341
399	O-linked_Glycosylation	PAEKSAVSTSVPTKP CCHHCCCCCCCCCCC	18.06	30059200
399	O-linked_Glycosylation	PAEKSAVSTSVPTKP CCHHCCCCCCCCCCC	18.06	20068230
399	Phosphorylation	PAEKSAVSTSVPTKP CCHHCCCCCCCCCCC	18.06	22115753
400	O-linked_Glycosylation	AEKSAVSTSVPTKPT CHHCCCCCCCCCCCC	27.43	30059200
400	O-linked_Glycosylation	AEKSAVSTSVPTKPT CHHCCCCCCCCCCCC	27.43	20068230
400	Phosphorylation	AEKSAVSTSVPTKPT CHHCCCCCCCCCCCC	27.43	22115753
401	O-linked_Glycosylation	EKSAVSTSVPTKPTE HHCCCCCCCCCCCCC	20.70	20068230
401	Phosphorylation	EKSAVSTSVPTKPTE HHCCCCCCCCCCCCC	20.70	22115753
404	O-linked_Glycosylation	AVSTSVPTKPTENIS CCCCCCCCCCCCCCC	47.72	20068230
404	Phosphorylation	AVSTSVPTKPTENIS CCCCCCCCCCCCCCC	47.72	22115753
405	Acetylation	VSTSVPTKPTENISK CCCCCCCCCCCCCCC	43.82	26051181
407	O-linked_Glycosylation	TSVPTKPTENISKAS CCCCCCCCCCCCCCC	43.13	20068230
411	O-linked_Glycosylation	TKPTENISKASSCTP CCCCCCCCCCCCCCC	33.48	20068230
414	O-linked_Glycosylation	TENISKASSCTPVPV CCCCCCCCCCCCCCE	29.68	20068230
414	Phosphorylation	TENISKASSCTPVPV CCCCCCCCCCCCCCE	29.68	32142685
415	Phosphorylation	ENISKASSCTPVPVT CCCCCCCCCCCCCEE	27.20	25627689
417	Phosphorylation	ISKASSCTPVPVTMT CCCCCCCCCCCEEEE	29.30	25159151
422	O-linked_Glycosylation	SCTPVPVTMTATPPL CCCCCCEEEEECCCC	11.61	20068230
422	Phosphorylation	SCTPVPVTMTATPPL CCCCCCEEEEECCCC	11.61	26074081
424	Phosphorylation	TPVPVTMTATPPLPK CCCCEEEEECCCCCC	20.29	25159151
426	Phosphorylation	VPVTMTATPPLPKPV CCEEEEECCCCCCCC	19.10	25159151
435	Phosphorylation	PLPKPVNTSLSPSPA CCCCCCCCCCCCCCC	31.14	29255136
436	O-linked_Glycosylation	LPKPVNTSLSPSPAL CCCCCCCCCCCCCCH	22.96	20068230
436	Phosphorylation	LPKPVNTSLSPSPAL CCCCCCCCCCCCCCH	22.96	28387310
438	O-linked_Glycosylation	KPVNTSLSPSPALAL CCCCCCCCCCCCHHC	24.09	20068230
438	Phosphorylation	KPVNTSLSPSPALAL CCCCCCCCCCCCHHC	24.09	29255136
440	O-linked_Glycosylation	VNTSLSPSPALALPN CCCCCCCCCCHHCCC	21.30	20068230
440	Phosphorylation	VNTSLSPSPALALPN CCCCCCCCCCHHCCC	21.30	29255136
456	Phosphorylation	ANVDLAKISSILSSL CCCCHHHHHHHHHHH	3.04	32142685
461	Phosphorylation	AKISSILSSLTSVMK HHHHHHHHHHHHHHH	22.95	18669648
462	Phosphorylation	KISSILSSLTSVMKN HHHHHHHHHHHHHHH	32.02	21815630
465	Phosphorylation	SILSSLTSVMKNTGV HHHHHHHHHHHHCCC	26.05	20068231
470	Phosphorylation	LTSVMKNTGVSPASR HHHHHHHCCCCCCCC	33.18	30266825
473	Phosphorylation	VMKNTGVSPASRPSP HHHHCCCCCCCCCCC	18.98	23401153
476	O-linked_Glycosylation	NTGVSPASRPSPGTP HCCCCCCCCCCCCCC	48.37	20068230
476	Phosphorylation	NTGVSPASRPSPGTP HCCCCCCCCCCCCCC	48.37	25159151
479	Phosphorylation	VSPASRPSPGTPTSP CCCCCCCCCCCCCCH	34.55	23927012
482	Phosphorylation	ASRPSPGTPTSPSNL CCCCCCCCCCCHHHC	27.12	22167270
484	Phosphorylation	RPSPGTPTSPSNLTS CCCCCCCCCHHHCCC	53.78	29255136
485	Phosphorylation	PSPGTPTSPSNLTSG CCCCCCCCHHHCCCC	27.77	29255136
487	Phosphorylation	PGTPTSPSNLTSGLK CCCCCCHHHCCCCCC	44.21	29255136
490	Phosphorylation	PTSPSNLTSGLKTPA CCCHHHCCCCCCCCC	25.62	30266825
491	Phosphorylation	TSPSNLTSGLKTPAP CCHHHCCCCCCCCCC	45.34	30266825
495	O-linked_Glycosylation	NLTSGLKTPAPATTT HCCCCCCCCCCCCCC	29.71	20068230
495	Phosphorylation	NLTSGLKTPAPATTT HCCCCCCCCCCCCCC	29.71	25159151
500	O-linked_Glycosylation	LKTPAPATTTSHNPL CCCCCCCCCCCCCHH	29.55	20068230
501	O-linked_Glycosylation	KTPAPATTTSHNPLA CCCCCCCCCCCCHHH	28.54	20068230
501	Phosphorylation	KTPAPATTTSHNPLA CCCCCCCCCCCCHHH	28.54	24667141
502	O-linked_Glycosylation	TPAPATTTSHNPLAN CCCCCCCCCCCHHHH	24.51	20068230
503	O-linked_Glycosylation	PAPATTTSHNPLANI CCCCCCCCCCHHHHH	21.12	20068230
512	Phosphorylation	NPLANILSKVEITPE CHHHHHHHHCCCCHH	30.75	25159151
513	Ubiquitination	PLANILSKVEITPES HHHHHHHHCCCCHHH	40.20	-
517	Phosphorylation	ILSKVEITPESILSA HHHHCCCCHHHHHHH	13.90	26055452
520	Phosphorylation	KVEITPESILSALSK HCCCCHHHHHHHHHH	29.99	24732914
528	O-linked_Glycosylation	ILSALSKTQTQSAPA HHHHHHHCCCCCCHH	33.21	20068230
540	O-linked_Glycosylation	APALQGLSSLLQSVT CHHHHHHHHHHHHHH	26.26	20068230
545	O-linked_Glycosylation	GLSSLLQSVTGNPVP HHHHHHHHHHCCCCC	22.93	20068230
547	O-linked_Glycosylation	SSLLQSVTGNPVPAS HHHHHHHHCCCCCHH	36.17	20068230
554	O-linked_Glycosylation	TGNPVPASEAASQST HCCCCCHHHHHHHCC	23.00	20068230
558	O-linked_Glycosylation	VPASEAASQSTSASP CCHHHHHHHCCCCCC	31.54	20068230
558	Phosphorylation	VPASEAASQSTSASP CCHHHHHHHCCCCCC	31.54	26074081
560	O-linked_Glycosylation	ASEAASQSTSASPAN HHHHHHHCCCCCCCC	23.10	20068230
560	Phosphorylation	ASEAASQSTSASPAN HHHHHHHCCCCCCCC	23.10	26074081
561	O-linked_Glycosylation	SEAASQSTSASPANT HHHHHHCCCCCCCCC	22.22	20068230
561	Phosphorylation	SEAASQSTSASPANT HHHHHHCCCCCCCCC	22.22	26074081
562	O-linked_Glycosylation	EAASQSTSASPANTT HHHHHCCCCCCCCCC	31.81	20068230
562	Phosphorylation	EAASQSTSASPANTT HHHHHCCCCCCCCCC	31.81	26074081
564	O-linked_Glycosylation	ASQSTSASPANTTVS HHHCCCCCCCCCCEE	25.06	20068230
564	Phosphorylation	ASQSTSASPANTTVS HHHCCCCCCCCCCEE	25.06	26074081
567	Phosphorylation	STSASPANTTVSTIK CCCCCCCCCCEEEEC	39.40	32142685
568	O-linked_Glycosylation	TSASPANTTVSTIKG CCCCCCCCCEEEECC	30.59	20068230
568	Phosphorylation	TSASPANTTVSTIKG CCCCCCCCCEEEECC	30.59	26074081
569	Phosphorylation	SASPANTTVSTIKGR CCCCCCCCEEEECCC	16.56	26074081
571	Phosphorylation	SPANTTVSTIKGRNL CCCCCCEEEECCCCC	23.48	18669648
572	O-linked_Glycosylation	PANTTVSTIKGRNLP CCCCCEEEECCCCCC	23.52	20068230
572	Phosphorylation	PANTTVSTIKGRNLP CCCCCEEEECCCCCC	23.52	20068231
580	Phosphorylation	IKGRNLPSSAQPFIP ECCCCCCCCCCCCCC	41.28	29978859
581	Phosphorylation	KGRNLPSSAQPFIPK CCCCCCCCCCCCCCC	29.05	20068231
588	Phosphorylation	SAQPFIPKSFNYSPN CCCCCCCCCCCCCCC	63.96	32142685
589	O-linked_Glycosylation	AQPFIPKSFNYSPNS CCCCCCCCCCCCCCC	17.23	20068230
589	Phosphorylation	AQPFIPKSFNYSPNS CCCCCCCCCCCCCCC	17.23	30278072
592	Phosphorylation	FIPKSFNYSPNSSTS CCCCCCCCCCCCCCC	24.40	30278072
593	Phosphorylation	IPKSFNYSPNSSTSE CCCCCCCCCCCCCCC	20.79	19664994
596	Phosphorylation	SFNYSPNSSTSEVSS CCCCCCCCCCCCCCC	38.07	25159151
597	O-linked_Glycosylation	FNYSPNSSTSEVSST CCCCCCCCCCCCCCC	42.46	20068230
597	Phosphorylation	FNYSPNSSTSEVSST CCCCCCCCCCCCCCC	42.46	25159151
598	Phosphorylation	NYSPNSSTSEVSSTS CCCCCCCCCCCCCCC	28.82	23927012
599	Phosphorylation	YSPNSSTSEVSSTSA CCCCCCCCCCCCCCC	37.64	23927012
602	Phosphorylation	NSSTSEVSSTSASKA CCCCCCCCCCCCHHC	24.69	23927012
603	Phosphorylation	SSTSEVSSTSASKAS CCCCCCCCCCCHHCC	31.40	23927012
604	O-linked_Glycosylation	STSEVSSTSASKASI CCCCCCCCCCHHCCC	22.32	20068230
604	Phosphorylation	STSEVSSTSASKASI CCCCCCCCCCHHCCC	22.32	23927012
605	Phosphorylation	TSEVSSTSASKASIG CCCCCCCCCHHCCCC	32.28	23927012
607	O-linked_Glycosylation	EVSSTSASKASIGQS CCCCCCCHHCCCCCC	28.64	20068230
607	Phosphorylation	EVSSTSASKASIGQS CCCCCCCHHCCCCCC	28.64	23927012
610	Phosphorylation	STSASKASIGQSPGL CCCCHHCCCCCCCCC	30.87	25159151
614	Phosphorylation	SKASIGQSPGLPSTT HHCCCCCCCCCCCCC	18.74	29255136
619	Phosphorylation	GQSPGLPSTTFKLPS CCCCCCCCCCEECCC	45.16	28176443
620	Phosphorylation	QSPGLPSTTFKLPSN CCCCCCCCCEECCCC	34.02	23403867
621	Phosphorylation	SPGLPSTTFKLPSNS CCCCCCCCEECCCCC	24.10	23403867
626	Phosphorylation	STTFKLPSNSLGFTA CCCEECCCCCCCCEE	49.87	25159151
628	O-linked_Glycosylation	TFKLPSNSLGFTATH CEECCCCCCCCEECC	33.92	20068230
628	Phosphorylation	TFKLPSNSLGFTATH CEECCCCCCCCEECC	33.92	29978859
632	Phosphorylation	PSNSLGFTATHNTSP CCCCCCCEECCCCCC	28.93	25159151
634	Phosphorylation	NSLGFTATHNTSPAA CCCCCEECCCCCCCC	16.76	29978859
637	Phosphorylation	GFTATHNTSPAAPPT CCEECCCCCCCCCCC	28.60	25627689
638	Phosphorylation	FTATHNTSPAAPPTE CEECCCCCCCCCCCE	20.19	29496963
639	Phosphorylation	TATHNTSPAAPPTEV EECCCCCCCCCCCEE	30.33	32142685
644	Phosphorylation	TSPAAPPTEVTICQS CCCCCCCCEEEEEEC	41.87	29978859
645	Ubiquitination	SPAAPPTEVTICQSS CCCCCCCEEEEEECC	43.36	29967540
647	Phosphorylation	AAPPTEVTICQSSEV CCCCCEEEEEECCCC	15.14	27080861
651	Ubiquitination	TEVTICQSSEVSKPK CEEEEEECCCCCCCC	24.85	29967540
656	Acetylation	CQSSEVSKPKLESES EECCCCCCCCCCCCC	51.88	26051181
661	Phosphorylation	VSKPKLESESTSPSL CCCCCCCCCCCCCCH	47.48	30266825
663	Phosphorylation	KPKLESESTSPSLEM CCCCCCCCCCCCHHH	43.39	30266825
664	Phosphorylation	PKLESESTSPSLEMK CCCCCCCCCCCHHHH	40.37	29255136
665	Phosphorylation	KLESESTSPSLEMKI CCCCCCCCCCHHHHH	23.05	29255136
667	Phosphorylation	ESESTSPSLEMKIHN CCCCCCCCHHHHHHH	36.41	29255136
670	Sulfoxidation	STSPSLEMKIHNFLK CCCCCHHHHHHHHHH	6.31	21406390
671	Acetylation	TSPSLEMKIHNFLKG CCCCHHHHHHHHHHC	31.29	25953088
671	Ubiquitination	TSPSLEMKIHNFLKG CCCCHHHHHHHHHHC	31.29	29967540
677	Ubiquitination	MKIHNFLKGNPGFSG HHHHHHHHCCCCCCC	53.13	29967540
697	Phosphorylation	PILSSLGSSAPSESH HHHHHCCCCCCCCCC	28.72	17081983
706	Phosphorylation	APSESHPSDFQRGPT CCCCCCCCCCCCCCC	45.71	32142685
708	Phosphorylation	SESHPSDFQRGPTST CCCCCCCCCCCCCCC	6.65	32142685
713	Phosphorylation	SDFQRGPTSTSIDNI CCCCCCCCCCCEECC	47.67	23927012
714	Phosphorylation	DFQRGPTSTSIDNID CCCCCCCCCCEECCC	24.24	29255136
715	Phosphorylation	FQRGPTSTSIDNIDG CCCCCCCCCEECCCC	31.98	29255136
716	Phosphorylation	QRGPTSTSIDNIDGT CCCCCCCCEECCCCC	27.93	29255136
723	Phosphorylation	SIDNIDGTPVRDERS CEECCCCCCCCCCCC	18.18	19664994
730	Phosphorylation	TPVRDERSGTPTQDE CCCCCCCCCCCCHHH	45.00	23927012
732	Phosphorylation	VRDERSGTPTQDEMM CCCCCCCCCCHHHHC	25.14	20201521
734	Phosphorylation	DERSGTPTQDEMMDK CCCCCCCCHHHHCCC	48.79	23927012
739	Phosphorylation	TPTQDEMMDKPTSSS CCCHHHHCCCCCCCC	5.88	32142685
741	Acetylation	TQDEMMDKPTSSSVD CHHHHCCCCCCCCHH	32.09	26051181
743	Phosphorylation	DEMMDKPTSSSVDTM HHHCCCCCCCCHHHH	47.16	30266825
744	Phosphorylation	EMMDKPTSSSVDTMS HHCCCCCCCCHHHHH	29.19	30266825
745	Phosphorylation	MMDKPTSSSVDTMSL HCCCCCCCCHHHHHH	36.54	23927012
746	Phosphorylation	MDKPTSSSVDTMSLL CCCCCCCCHHHHHHH	24.63	23927012
749	Phosphorylation	PTSSSVDTMSLLSKI CCCCCHHHHHHHHHH	13.40	23927012
751	Phosphorylation	SSSVDTMSLLSKIIS CCCHHHHHHHHHHCC	28.40	23927012
754	Phosphorylation	VDTMSLLSKIISPGS HHHHHHHHHHCCCCC	27.40	23927012
758	Phosphorylation	SLLSKIISPGSSTPS HHHHHHCCCCCCCCC	27.04	23401153
761	Phosphorylation	SKIISPGSSTPSSTR HHHCCCCCCCCCCCC	34.13	30266825
762	O-linked_Glycosylation	KIISPGSSTPSSTRS HHCCCCCCCCCCCCC	50.69	20068230
762	Phosphorylation	KIISPGSSTPSSTRS HHCCCCCCCCCCCCC	50.69	30266825
763	Phosphorylation	IISPGSSTPSSTRSP HCCCCCCCCCCCCCC	28.96	29255136
765	Phosphorylation	SPGSSTPSSTRSPPP CCCCCCCCCCCCCCC	44.42	23401153
766	Phosphorylation	PGSSTPSSTRSPPPG CCCCCCCCCCCCCCC	29.10	30266825
767	Phosphorylation	GSSTPSSTRSPPPGR CCCCCCCCCCCCCCC	39.23	30266825
769	Phosphorylation	STPSSTRSPPPGRDE CCCCCCCCCCCCCCC	41.67	25159151
772	Phosphorylation	SSTRSPPPGRDESYP CCCCCCCCCCCCCCC	54.56	32142685
777	Phosphorylation	PPPGRDESYPRELSN CCCCCCCCCCCHHHC	44.73	30266825
778	Phosphorylation	PPGRDESYPRELSNS CCCCCCCCCCHHHCC	12.31	23898821
783	Phosphorylation	ESYPRELSNSVSTYR CCCCCHHHCCCCCCC	23.47	23403867
785	Phosphorylation	YPRELSNSVSTYRPF CCCHHHCCCCCCCCC	17.67	25159151
787	Phosphorylation	RELSNSVSTYRPFGL CHHHCCCCCCCCCCC	21.39	21955146
788	Phosphorylation	ELSNSVSTYRPFGLG HHHCCCCCCCCCCCC	22.76	21955146
789	Phosphorylation	LSNSVSTYRPFGLGS HHCCCCCCCCCCCCC	14.58	21955146
796	Phosphorylation	YRPFGLGSESPYKQP CCCCCCCCCCCCCCC	39.69	29255136
798	Phosphorylation	PFGLGSESPYKQPSD CCCCCCCCCCCCCCC	34.92	29255136
800	Phosphorylation	GLGSESPYKQPSDGM CCCCCCCCCCCCCCC	31.38	29255136
804	Phosphorylation	ESPYKQPSDGMERPS CCCCCCCCCCCCCCH	44.28	30576142
811	Phosphorylation	SDGMERPSSLMDSSQ CCCCCCCHHHCCCCC	42.18	23403867
812	Phosphorylation	DGMERPSSLMDSSQE CCCCCCHHHCCCCCC	30.32	26074081
816	Phosphorylation	RPSSLMDSSQEKFYP CCHHHCCCCCCCCCC	21.69	29255136
817	Phosphorylation	PSSLMDSSQEKFYPD CHHHCCCCCCCCCCC	37.79	17525332
822	Phosphorylation	DSSQEKFYPDTSFQE CCCCCCCCCCCCCCC	15.97	28450419
825	Phosphorylation	QEKFYPDTSFQEDED CCCCCCCCCCCCCCC	27.26	28450419
826	Phosphorylation	EKFYPDTSFQEDEDY CCCCCCCCCCCCCCC	32.11	21130716
833	Phosphorylation	SFQEDEDYRDFEYSG CCCCCCCCCCCCCCC	15.27	28450419
838	Phosphorylation	EDYRDFEYSGPPPSA CCCCCCCCCCCCCHH	20.94	27251275
839	Phosphorylation	DYRDFEYSGPPPSAM CCCCCCCCCCCCHHH	37.31	27251275
856	Phosphorylation	LEKKPAKSILKSSKL CCCCCHHHHHHHCCC	34.95	24719451
860	Phosphorylation	PAKSILKSSKLSDTT CHHHHHHHCCCCCCC	29.29	30108239
861	Phosphorylation	AKSILKSSKLSDTTE HHHHHHHCCCCCCCC	35.71	30108239
862	Acetylation	KSILKSSKLSDTTEY HHHHHHCCCCCCCCC	60.13	25953088
864	O-linked_Glycosylation	ILKSSKLSDTTEYQP HHHHCCCCCCCCCHH	36.33	20068230
864	Phosphorylation	ILKSSKLSDTTEYQP HHHHCCCCCCCCCHH	36.33	30576142
866	Phosphorylation	KSSKLSDTTEYQPIL HHCCCCCCCCCHHHH	20.39	28450419
867	Phosphorylation	SSKLSDTTEYQPILS HCCCCCCCCCHHHHH	37.37	28450419
869	Phosphorylation	KLSDTTEYQPILSSY CCCCCCCCHHHHHHH	19.93	28450419
874	Phosphorylation	TEYQPILSSYSHRAQ CCCHHHHHHHHHHHH	28.13	18669648
877	Phosphorylation	QPILSSYSHRAQEFG HHHHHHHHHHHHHHC	14.40	28555341
883	Phosphorylation	YSHRAQEFGVKSAFP HHHHHHHHCCCCCCC	10.16	32142685
899	Phosphorylation	SVRALLDSSENCDRL HHHHHHHCCCCCCHH	39.25	21815630
899 (in isoform 5)	Phosphorylation	-	39.25	25850435
900	Phosphorylation	VRALLDSSENCDRLS HHHHHHCCCCCCHHC	32.28	25159151
902 (in isoform 5)	Phosphorylation	-	34.63	25849741
904 (in isoform 5)	Phosphorylation	-	67.16	25849741
907	Phosphorylation	SENCDRLSSSPGLFG CCCCCHHCCCCCCCC	29.66	25159151
908	Phosphorylation	ENCDRLSSSPGLFGA CCCCHHCCCCCCCCE	45.18	29255136
909	Phosphorylation	NCDRLSSSPGLFGAF CCCHHCCCCCCCCEE	21.44	29255136
911 (in isoform 5)	Phosphorylation	-	35.27	28176443
914 (in isoform 5)	Phosphorylation	-	30.65	25849741
916 (in isoform 5)	Phosphorylation	-	7.69	28176443
917	Phosphorylation	PGLFGAFSVRGNEPG CCCCCEEEECCCCCC	15.46	23403867
923 (in isoform 5)	Phosphorylation	-	52.14	25849741
925	Phosphorylation	VRGNEPGSDRSPSPS ECCCCCCCCCCCCCC	40.33	29255136
928	Phosphorylation	NEPGSDRSPSPSKND CCCCCCCCCCCCCCC	34.42	29255136
930	Phosphorylation	PGSDRSPSPSKNDSF CCCCCCCCCCCCCCC	42.95	29255136
932	Phosphorylation	SDRSPSPSKNDSFFT CCCCCCCCCCCCCCC	48.72	23927012
936	Phosphorylation	PSPSKNDSFFTPDSN CCCCCCCCCCCCCCC	31.49	25159151
939	Phosphorylation	SKNDSFFTPDSNHNS CCCCCCCCCCCCCCC	24.95	25159151
942	Phosphorylation	DSFFTPDSNHNSLSQ CCCCCCCCCCCCCCC	40.99	25159151
946	Phosphorylation	TPDSNHNSLSQSTTG CCCCCCCCCCCCCCC	23.11	23927012
947	Phosphorylation	PDSNHNSLSQSTTGH CCCCCCCCCCCCCCC	7.01	32142685
948	Phosphorylation	DSNHNSLSQSTTGHL CCCCCCCCCCCCCCC	23.16	23927012
950	Phosphorylation	NHNSLSQSTTGHLSL CCCCCCCCCCCCCCC	25.26	25159151
951	Phosphorylation	HNSLSQSTTGHLSLP CCCCCCCCCCCCCCC	29.21	30206219
952	Phosphorylation	NSLSQSTTGHLSLPQ CCCCCCCCCCCCCCH	28.05	30206219
956	Phosphorylation	QSTTGHLSLPQKQYP CCCCCCCCCCHHHCC	32.12	20068231
962	Phosphorylation	LSLPQKQYPDSPHPV CCCCHHHCCCCCCCC	18.95	30266825
965	Phosphorylation	PQKQYPDSPHPVPHR CHHHCCCCCCCCCCH	22.17	30266825
973	Phosphorylation	PHPVPHRSLFSPQNT CCCCCCHHCCCCCCC	30.63	30266825
976	Phosphorylation	VPHRSLFSPQNTLAA CCCHHCCCCCCCCCC	30.76	23927012
980	Phosphorylation	SLFSPQNTLAAPTGH HCCCCCCCCCCCCCC	16.72	30266825
985	O-linked_Glycosylation	QNTLAAPTGHPPTSG CCCCCCCCCCCCCCC	43.31	20068230
985	Phosphorylation	QNTLAAPTGHPPTSG CCCCCCCCCCCCCCC	43.31	23403867
988	Ubiquitination	LAAPTGHPPTSGVEK CCCCCCCCCCCCHHH	34.90	29967540
990	O-linked_Glycosylation	APTGHPPTSGVEKVL CCCCCCCCCCHHHHH	42.43	20068230
990	Phosphorylation	APTGHPPTSGVEKVL CCCCCCCCCCHHHHH	42.43	23403867
991	O-linked_Glycosylation	PTGHPPTSGVEKVLA CCCCCCCCCHHHHHH	46.76	20068230
991	Phosphorylation	PTGHPPTSGVEKVLA CCCCCCCCCHHHHHH	46.76	23403867
1006	Ubiquitination	STISTTSTIEFKNML HHCCCCCCHHHHHHH	23.57	29967540
1014	Ubiquitination	IEFKNMLKNASRKPS HHHHHHHHHCCCCCC	39.43	29967540
1017	Phosphorylation	KNMLKNASRKPSDDK HHHHHHCCCCCCCCC	50.67	20068231
1021	Phosphorylation	KNASRKPSDDKHFGQ HHCCCCCCCCCCCCC	62.57	26657352
1024	Acetylation	SRKPSDDKHFGQAPS CCCCCCCCCCCCCCC	45.91	26051181
1031	Phosphorylation	KHFGQAPSKGTPSDG CCCCCCCCCCCCCCC	46.89	23312004
1032	Acetylation	HFGQAPSKGTPSDGV CCCCCCCCCCCCCCC	66.79	26051181
1032	Ubiquitination	HFGQAPSKGTPSDGV CCCCCCCCCCCCCCC	66.79	29967540
1034	Phosphorylation	GQAPSKGTPSDGVSL CCCCCCCCCCCCCCH	24.29	25159151
1036	Phosphorylation	APSKGTPSDGVSLSN CCCCCCCCCCCCHHH	47.00	25627689
1068	O-linked_Glycosylation	YRIETRVSSSCLDLP HCCEECCCCHHCCCC	17.16	20068230
1068	Phosphorylation	YRIETRVSSSCLDLP HCCEECCCCHHCCCC	17.16	23401153
1069	Phosphorylation	RIETRVSSSCLDLPD CCEECCCCHHCCCCC	23.39	25159151
1070	Phosphorylation	IETRVSSSCLDLPDS CEECCCCHHCCCCCC	15.93	16964243
1073	Phosphorylation	RVSSSCLDLPDSTEE CCCCHHCCCCCCCCC	61.56	32142685
1087	Phosphorylation	EKGAPIETLGYHSAS CCCCCCHHCEEECCC	26.63	23882029
1090	Phosphorylation	APIETLGYHSASNRR CCCHHCEEECCCCCC	8.84	25159151
1092	Phosphorylation	IETLGYHSASNRRMS CHHCEEECCCCCCCC	25.55	25159151
1094	Phosphorylation	TLGYHSASNRRMSGE HCEEECCCCCCCCCC	33.61	23882029
1099	Phosphorylation	SASNRRMSGEPIQTV CCCCCCCCCCCCCEE	37.89	29255136
1105	Phosphorylation	MSGEPIQTVESIRVP CCCCCCCEEEEEECC	27.28	23927012
1108	Phosphorylation	EPIQTVESIRVPGKG CCCCEEEEEECCCCC	16.03	23927012
1117	Methylation	RVPGKGNRGHGREAS ECCCCCCCCCCCCCC	47.34	115387017
1132	Phosphorylation	RVGWFDLSTSGSSFD CCCCEEECCCCCCCC	23.52	30624053
1133	Phosphorylation	VGWFDLSTSGSSFDN CCCEEECCCCCCCCC	44.39	30624053
1134	Phosphorylation	GWFDLSTSGSSFDNG CCEEECCCCCCCCCC	33.05	30624053
1136	Phosphorylation	FDLSTSGSSFDNGPS EEECCCCCCCCCCCC	27.83	30624053
1137	Phosphorylation	DLSTSGSSFDNGPSS EECCCCCCCCCCCCC	39.90	28464451
1143	Phosphorylation	SSFDNGPSSASELAS CCCCCCCCCHHHHHH	39.68	30624053
1144	Phosphorylation	SFDNGPSSASELASL CCCCCCCCHHHHHHC	38.66	30624053
1146	Phosphorylation	DNGPSSASELASLGG CCCCCCHHHHHHCCC	34.78	28464451
1177	Phosphorylation	RAPQFQESVGSFRSN CCHHHHHHHHCCCCC	22.46	28555341
1180	Phosphorylation	QFQESVGSFRSNSFN HHHHHHHCCCCCCCC	18.48	23401153
1183	Phosphorylation	ESVGSFRSNSFNSTF HHHHCCCCCCCCCCC	34.51	29255136
1185	Phosphorylation	VGSFRSNSFNSTFEH HHCCCCCCCCCCCCC	27.35	29255136
1188	Phosphorylation	FRSNSFNSTFEHHLP CCCCCCCCCCCCCCC	32.25	29255136
1189	Phosphorylation	RSNSFNSTFEHHLPP CCCCCCCCCCCCCCC	33.86	29255136
1197	Phosphorylation	FEHHLPPSPLEHGTP CCCCCCCCCCCCCCC	39.93	29255136
1203	Phosphorylation	PSPLEHGTPFQREPV CCCCCCCCCCCCCCC	23.88	29255136
1214	Phosphorylation	REPVGPSSAPPVPPK CCCCCCCCCCCCCCC	48.18	28674419
1228	Phosphorylation	KDHGGIFSRDAPTHL CCCCCCCCCCCCCCC	27.59	28348404
1233	Phosphorylation	IFSRDAPTHLPSVDL CCCCCCCCCCCCCCC	37.45	27080861
1237	Phosphorylation	DAPTHLPSVDLSNPF CCCCCCCCCCCCCCC	34.32	29083192
1330	Phosphorylation	VFPKDHSSLLQGTLA EECCCHHHHHHHHHH	29.67	28555341
1363	Phosphorylation	DLNGPGLSRVRESLT CCCCCCHHHHHHHHC	34.34	28122231
1366	Asymmetric dimethylarginine	GPGLSRVRESLTLPS CCCHHHHHHHHCCCC	27.03	-
1366	Methylation	GPGLSRVRESLTLPS CCCHHHHHHHHCCCC	27.03	24129315
1368	Phosphorylation	GLSRVRESLTLPSHS CHHHHHHHHCCCCCC	18.98	-
1370	Phosphorylation	SRVRESLTLPSHSLE HHHHHHHCCCCCCHH	45.99	-
1406	Phosphorylation	LGPSHRDTISRSGII CCCCCCCCCCCCCEE	22.32	19664995
1408	Phosphorylation	PSHRDTISRSGIILR CCCCCCCCCCCEEEC	23.61	19664995
1415	Dimethylation	SRSGIILRSPRPDFR CCCCEEECCCCCCCC	33.92	-
1415	Methylation	SRSGIILRSPRPDFR CCCCEEECCCCCCCC	33.92	54549673
1416	Phosphorylation	RSGIILRSPRPDFRP CCCEEECCCCCCCCC	23.09	22817900
1418	Dimethylation	GIILRSPRPDFRPRE CEEECCCCCCCCCCC	44.67	-
1418	Methylation	GIILRSPRPDFRPRE CEEECCCCCCCCCCC	44.67	54549477
1422	Dimethylation	RSPRPDFRPREPFLS CCCCCCCCCCCCCCC	36.42	-
1422	Methylation	RSPRPDFRPREPFLS CCCCCCCCCCCCCCC	36.42	54561765
1424	Asymmetric dimethylarginine	PRPDFRPREPFLSRD CCCCCCCCCCCCCCC	61.02	-
1424	Methylation	PRPDFRPREPFLSRD CCCCCCCCCCCCCCC	61.02	24129315
1429	Phosphorylation	RPREPFLSRDPFHSL CCCCCCCCCCCCCCC	34.71	23898821
1430	Asymmetric dimethylarginine	PREPFLSRDPFHSLK CCCCCCCCCCCCCCC	58.74	-
1430	Methylation	PREPFLSRDPFHSLK CCCCCCCCCCCCCCC	58.74	24129315
1435	Phosphorylation	LSRDPFHSLKRPRPP CCCCCCCCCCCCCCC	35.65	23898821
1454	Dimethylation	PPFFAPKRPFFPPRY CCCCCCCCCCCCCCC	32.00	-
1454	Methylation	PPFFAPKRPFFPPRY CCCCCCCCCCCCCCC	32.00	30763079
1460	Dimethylation	KRPFFPPRY------ CCCCCCCCC------	50.46	-
1460	Methylation	KRPFFPPRY------ CCCCCCCCC------	50.46	30763085

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RPRD2_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RPRD2_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RPRD2_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of RPRD2_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Quantitative phosphoproteomic analysis of T cell receptor signalingreveals system-wide modulation of protein-protein interactions.";
Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K.,Rodionov V., Han D.K.;
Sci. Signal. 2:RA46-RA46(2009).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-374; SER-473; SER-476;THR-482; SER-485; SER-593; THR-598; SER-614; SER-665; THR-723;THR-732; SER-826; SER-909 AND SER-1099, AND MASS SPECTROMETRY.
PubMed: 19690332

"A quantitative atlas of mitotic phosphorylation.";
Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,Elledge S.J., Gygi S.P.;
Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-374; SER-479; THR-482;SER-485; SER-487; THR-517; SER-593; SER-614; THR-723; SER-730;THR-732; SER-758; THR-763; SER-769; SER-900; SER-907; SER-909;SER-928; SER-932 AND SER-1099, AND MASS SPECTROMETRY.
PubMed: 18669648

"Phosphorylation analysis of primary human T lymphocytes usingsequential IMAC and titanium oxide enrichment.";
Carrascal M., Ovelleiro D., Casas V., Gay M., Abian J.;
J. Proteome Res. 7:5167-5176(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-374, AND MASSSPECTROMETRY.
PubMed: 19367720

"Combining protein-based IMAC, peptide-based IMAC, and MudPIT forefficient phosphoproteomic analysis.";
Cantin G.T., Yi W., Lu B., Park S.K., Xu T., Lee J.-D.,Yates J.R. III;
J. Proteome Res. 7:1346-1351(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-732; THR-734 ANDSER-909, AND MASS SPECTROMETRY.
PubMed: 18220336

"ATM and ATR substrate analysis reveals extensive protein networksresponsive to DNA damage.";
Matsuoka S., Ballif B.A., Smogorzewska A., McDonald E.R. III,Hurov K.E., Luo J., Bakalarski C.E., Zhao Z., Solimini N.,Lerenthal Y., Shiloh Y., Gygi S.P., Elledge S.J.;
Science 316:1160-1166(2007).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-817, AND MASSSPECTROMETRY.
PubMed: 17525332

"Improved titanium dioxide enrichment of phosphopeptides from HeLacells and high confident phosphopeptide identification by cross-validation of MS/MS and MS/MS/MS spectra.";
Yu L.-R., Zhu Z., Chan K.C., Issaq H.J., Dimitrov D.S., Veenstra T.D.;
J. Proteome Res. 6:4150-4162(2007).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-976, AND MASSSPECTROMETRY.
PubMed: 17924679

"A probability-based approach for high-throughput proteinphosphorylation analysis and site localization.";
Beausoleil S.A., Villen J., Gerber S.A., Rush J., Gygi S.P.;
Nat. Biotechnol. 24:1285-1292(2006).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-614; SER-758 ANDSER-762, AND MASS SPECTROMETRY.
PubMed: 16964243

"Global, in vivo, and site-specific phosphorylation dynamics insignaling networks.";
Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P.,Mann M.;
Cell 127:635-648(2006).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-356; THR-358; SER-374;THR-723 AND SER-1099, AND MASS SPECTROMETRY.
PubMed: 17081983

"Automated phosphoproteome analysis for cultured cancer cells by two-dimensional nanoLC-MS using a calcined titania/C18 biphasic column.";
Imami K., Sugiyama N., Kyono Y., Tomita M., Ishihama Y.;
Anal. Sci. 24:161-166(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-723, AND MASSSPECTROMETRY.
PubMed: 18187866