PDRG1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: PDRG1_HUMAN
• UniProt AC: Q9NUG6
• Protein Name: p53 and DNA damage-regulated protein 1
• Gene Name: PDRG1
• Organism: Homo sapiens (Human).
• Sequence Length: 133
• Subcellular Localization: Cytoplasm .
• Protein Description: May play a role in chaperone-mediated protein folding..
• Protein Sequence: MLSPEAERVLRYLVEVEELAEEVLADKRQIVDLDTKRNQNREGLRALQKDLSLSEDVMVCFGNMFIKMPHPETKEMIEKDQDHLDKEIEKLRKQLKVKVNRLFEAQGKPELKGFNLNPLNQDELKALKVILKG

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
3	Phosphorylation	-----MLSPEAERVL -----CCCHHHHHHH	21.28	29255136
27	Ubiquitination	AEEVLADKRQIVDLD HHHHHCCCHHHCCCC	40.36	2190698
36	Ubiquitination	QIVDLDTKRNQNREG HHCCCCHHCCCCHHH	49.36	-
52	Phosphorylation	RALQKDLSLSEDVMV HHHHHHCCCCCCEEH	39.73	-
54	Phosphorylation	LQKDLSLSEDVMVCF HHHHCCCCCCEEHHH	28.51	-
74	Ubiquitination	KMPHPETKEMIEKDQ CCCCHHHHHHHHHCH	43.56	-
108	Ubiquitination	RLFEAQGKPELKGFN HHHHHCCCCCCCCCC	24.20	-
112	Ubiquitination	AQGKPELKGFNLNPL HCCCCCCCCCCCCCC	60.85	-
125	Ubiquitination	PLNQDELKALKVILK CCCHHHHHHHHHHHC	50.02	-
128	Ubiquitination	QDELKALKVILKG-- HHHHHHHHHHHCC--	31.89	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of PDRG1_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of PDRG1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of PDRG1_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
PFD2_HUMAN	PFDN2	physical	22939629
PFD4_HUMAN	PFDN4	physical	22939629
RS3A_HUMAN	RPS3A	physical	22939629
ACY1_HUMAN	ACY1	physical	26344197
RMP_HUMAN	URI1	physical	26344197

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.