ZN667_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ZN667_HUMAN
• UniProt AC: Q5HYK9
• Protein Name: Zinc finger protein 667
• Gene Name: ZNF667
• Organism: Homo sapiens (Human).
• Sequence Length: 610
• Subcellular Localization: Nucleus .
• Protein Description: May be involved in transcriptional regulation..
• Protein Sequence: MPSARGKSKSKAPITFGDLAIYFSQEEWEWLSPIQKDLYEDVMLENYRNLVSLGLSFRRPNVITLLEKGKAPWMVEPVRRRRAPDSGSKCETKKLPPNQCNKSGQSICQKLVSAQQKAPTRKSGCNKNSVLVKPKKGHSGKKPLKCNDCGKTFSRSFSLKLHQNIHTGEKPFECSNCRKAFRQISSILLHQRIHSGKKSHECNKCGESFNQRTTLILHMRIHDGKEILDCGKALSQCQSFNIHQKIHVVGNVCQCRKCGKAFNQMSSLLLHKKIHNGKKTHKYNKCGRGFKKKSVFVVHKRIHAGEKIPENAKALSQSLQQRSHHLENPFKCRKCGKLFNRISPLMLHQRIHTSEKPYKCDKCDKFFRRLSTLILHLRIHNGEKLYRCNKCEKVCNRHSSLIQHQKVHTKKKKLFECKECGKMFSGTANLKIHQNIHSEEKPFKCNKCSKVFGRQSFLIEHQRIHTGEKPYQCEECGKAFSHRISLTRHKRIHTEDRPYECDQCGKAFSQSAHLAQHERIHTGEKPYTCKTCGKAFSQRTSLILHERSHTGEKPYECNECGKAFSSGSDLIRHQRSHSSEKPYECSKCGKAYSRSSSLIRHQNTHSEEKA

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
8	Phosphorylation	MPSARGKSKSKAPIT CCCCCCCCCCCCCCC	45.01	-
10	Phosphorylation	SARGKSKSKAPITFG CCCCCCCCCCCCCHH	40.93	-
86	Phosphorylation	RRRRAPDSGSKCETK CCCCCCCCCCCCCCC	43.86	-
88	Phosphorylation	RRAPDSGSKCETKKL CCCCCCCCCCCCCCC	37.78	-
103	Phosphorylation	PPNQCNKSGQSICQK CHHHCCCHHHHHHHH	28.24	19845377
106	Phosphorylation	QCNKSGQSICQKLVS HCCCHHHHHHHHHHH	28.93	30622161
129	Phosphorylation	KSGCNKNSVLVKPKK CCCCCCCCEEECCCC	20.59	28509920
141	Acetylation	PKKGHSGKKPLKCND CCCCCCCCCCCCCCC	54.99	24846233
156	Phosphorylation	CGKTFSRSFSLKLHQ CCCEECHHHEEEECC	20.28	24719451
158	Phosphorylation	KTFSRSFSLKLHQNI CEECHHHEEEECCCC	26.33	24719451
167	Phosphorylation	KLHQNIHTGEKPFEC EECCCCCCCCCCCCC	43.15	28509920
208	Phosphorylation	ECNKCGESFNQRTTL HCCCCCCCHHHCCEE	18.12	23403867
213	Phosphorylation	GESFNQRTTLILHMR CCCHHHCCEEEEEEE	19.05	29083192
214	Phosphorylation	ESFNQRTTLILHMRI CCHHHCCEEEEEEEE	17.62	29083192
393	Acetylation	YRCNKCEKVCNRHSS EECCCHHHHHHHCHH	62.65	19818033
466	Phosphorylation	IEHQRIHTGEKPYQC EEECCCCCCCCCEEC	44.67	28111955
469	Ubiquitination	QRIHTGEKPYQCEEC CCCCCCCCCEECHHH	50.82	-
485	Phosphorylation	KAFSHRISLTRHKRI HHHHCCCCCCCCCCC	24.52	24719451
509	Phosphorylation	DQCGKAFSQSAHLAQ CCHHHHHHHHHHHHH	28.25	-
511	Phosphorylation	CGKAFSQSAHLAQHE HHHHHHHHHHHHHHC	19.23	-
522	Phosphorylation	AQHERIHTGEKPYTC HHHCCCCCCCCCEEC	44.67	27732954
527	Phosphorylation	IHTGEKPYTCKTCGK CCCCCCCEECCCCCH	35.52	-
528	Phosphorylation	HTGEKPYTCKTCGKA CCCCCCEECCCCCHH	18.96	-
531	Phosphorylation	EKPYTCKTCGKAFSQ CCCEECCCCCHHHHH	28.74	29449344
537	Phosphorylation	KTCGKAFSQRTSLIL CCCCHHHHHCCEEEE	24.50	29449344
540	Phosphorylation	GKAFSQRTSLILHER CHHHHHCCEEEEEEC	21.90	29449344
541	Phosphorylation	KAFSQRTSLILHERS HHHHHCCEEEEEECC	18.66	29449344
550	Phosphorylation	ILHERSHTGEKPYEC EEEECCCCCCCCEEC	48.56	28674419
553	Ubiquitination	ERSHTGEKPYECNEC ECCCCCCCCEECCCC	55.00	-
565	Phosphorylation	NECGKAFSSGSDLIR CCCCCCCCCHHHHHH	38.35	23532336
596	Phosphorylation	GKAYSRSSSLIRHQN CCCCCCHHHHHHCCC	28.22	24719451
597	Phosphorylation	KAYSRSSSLIRHQNT CCCCCHHHHHHCCCC	29.12	24719451

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ZN667_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ZN667_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ZN667_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of ZN667_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.