SPC1L_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: SPC1L_HUMAN
• UniProt AC: Q9H0A9
• Protein Name: Speriolin-like protein
• Gene Name: SPATC1L
• Organism: Homo sapiens (Human).
• Sequence Length: 340
• Protein Sequence: MAEGGELMSRLLSENADLKKQVRLLKENQMLRRLLSQSCQEGGGHDLLPPRAHAYPEAGSPGSGVPDFGRFTSVADTPSQLQTSSLEDLLCSHAPLSSEDDTSPGCAAPSQAPFKAFLSPPEPHSHRGTDRKLSPLLSPLQDSLVDKTLLEPREMVRPKKVCFSESSLPTGDRTRRSYYLNEIQSFAGAEKDARVVGEIAFQLDRRILAYVFPGVTRLYGFTVANIPEKIEQTSTKSLDGSVDERKLRELTQRYLALSARLEKLGYSRDVHPAFSEFLINTYGILKQRPDLRANPLHSSPAALRKLVIDVVPPKFLGDSLLLLNCLCELSKEDGKPLFAW

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
60	Phosphorylation	HAYPEAGSPGSGVPD CCCCCCCCCCCCCCC		-
82	Ubiquitination	ADTPSQLQTSSLEDL CCCHHHHCCCCHHHH		29967540
134	Phosphorylation	RGTDRKLSPLLSPLQ CCCCCCCHHHCHHHC		-
151	Ubiquitination	LVDKTLLEPREMVRP HCCCCCCCHHHHHCC		29967540
181	Ubiquitination	TRRSYYLNEIQSFAG CHHHHHHHHHHHHCC		29967540
191	Ubiquitination	QSFAGAEKDARVVGE HHHCCCCCCHHHHHH		-
219	Phosphorylation	FPGVTRLYGFTVANI CCCHHHHCCEEECCC		24076635
229	Ubiquitination	TVANIPEKIEQTSTK EECCCCHHHHHCCCC		-
233	Phosphorylation	IPEKIEQTSTKSLDG CCHHHHHCCCCCCCC		24076635
234	Phosphorylation	PEKIEQTSTKSLDGS CHHHHHCCCCCCCCC		24076635
236	Ubiquitination	KIEQTSTKSLDGSVD HHHHCCCCCCCCCCC		29967540
237	Phosphorylation	IEQTSTKSLDGSVDE HHHCCCCCCCCCCCH		27499020
241	Phosphorylation	STKSLDGSVDERKLR CCCCCCCCCCHHHHH		24076635
251	Phosphorylation	ERKLRELTQRYLALS HHHHHHHHHHHHHHH		29449344
254	Phosphorylation	LRELTQRYLALSARL HHHHHHHHHHHHHHH		29449344
258	Phosphorylation	TQRYLALSARLEKLG HHHHHHHHHHHHHHC		29449344
263	Ubiquitination	ALSARLEKLGYSRDV HHHHHHHHHCCCCCC		-
286	Ubiquitination	INTYGILKQRPDLRA HHHHHHHHHCCCCCC		-
298	Phosphorylation	LRANPLHSSPAALRK CCCCCCCCCHHHHHH		-
305	Ubiquitination	SSPAALRKLVIDVVP CCHHHHHHHHHHCCC		29967540
335	Ubiquitination	ELSKEDGKPLFAW-- HHCCCCCCCCCCC--		29967540

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of SPC1L_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of SPC1L_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of SPC1L_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
LZTS2_HUMAN	LZTS2	physical	25416956
FSD2_HUMAN	FSD2	physical	25416956

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.