FSD2_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: FSD2_HUMAN
• UniProt AC: A1L4K1
• Protein Name: Fibronectin type III and SPRY domain-containing protein 2
• Gene Name: FSD2
• Organism: Homo sapiens (Human).
• Sequence Length: 749
• Protein Sequence: MEEESGEELGLDRSTPKDFHFYHMDLYDSEDRLHLFPEENTRMRKVVQAEMANESRGAGDGKAQRDLQEEVDELVHLYGLEDDHELGDEFVDENIPRTGVSEYPPYMMKRRDPAREQRDWRLSGEAAEAEDLGFGGWGSAGQCQDLREAYRYTHGRASEEYECYVIPEEEDEEEAADVFCVTCKTPIRAFQKVFDEHKEHEVIPLNEALESAKDEIHKNMYKLEKQIIEMENFANHLEEVFITVEENFGKQEQNFESHYNEILETLAQKYEEKIQALGEKKKEKLEALYGQLVSCGENLDTCKELMETIEEMCHEEKVDFIKDAVAMADRLGKFLKTKTDVEISAQPEFEDQTLDFSDVEQLMGSINTIPAPSAPVINPQVPNSATGSSVRVCWSLYSDDTVESYQLSYRPVQDSSPGTDQAEFTVTVKETYCSVTNLVPNTQYEFWVTAHNRAGPSPSSERAVYMTAPSPPIIKTKEIRSCEEAVLICWESGNLNPVDSYTVELTQAESPEASGVTESVVGIPTCESVVQLQPGRSYIIYVRALNMGGPSVRSEPATVHTIGSYFRLNKDTCHPWLTISEDGLTAVRSERRTPARELSPSDTHFTRCVAVMGNLIPVRGHHYWEVEVDEHLDYRVGVAFADVRKQEDLGANCLSWCMRHTFASSRHKYEFLHNRTTPDIRITVPPKKIGILLDYEHSKLSFFNVDLSQHLYTFSCQLHEFVHPCFSLEKPGCLKVHNGISMPKHVTFY

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
5	Phosphorylation	---MEEESGEELGLD ---CCCCCCCCCCCC	55.58	22673903
41	Phosphorylation	HLFPEENTRMRKVVQ ECCCCCCHHHHHHHH	29.17	24719451
289	Phosphorylation	KEKLEALYGQLVSCG HHHHHHHHHHHHHCC	15.18	22210691
301	Phosphorylation	SCGENLDTCKELMET HCCCCHHHHHHHHHH	28.74	22210691
457	Phosphorylation	AHNRAGPSPSSERAV ECCCCCCCCCCCCEE	36.17	22468782
465	Phosphorylation	PSSERAVYMTAPSPP CCCCCEEEEECCCCC	6.43	22817900
467	Phosphorylation	SERAVYMTAPSPPII CCCEEEEECCCCCCC	20.10	22817900
476	Phosphorylation	PSPPIIKTKEIRSCE CCCCCCCCCCCCCCC	24.41	22817900
538	Phosphorylation	QLQPGRSYIIYVRAL ECCCCCEEEEEEEEE	7.03	-
541	Phosphorylation	PGRSYIIYVRALNMG CCCEEEEEEEEECCC	3.70	-
599	Phosphorylation	RTPARELSPSDTHFT CCCCCCCCCCCCHHH	20.01	26437602
601	Phosphorylation	PARELSPSDTHFTRC CCCCCCCCCCHHHHH	52.33	22673903

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of FSD2_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of FSD2_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of FSD2_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
ZN572_HUMAN	ZNF572	physical	25416956
ZN417_HUMAN	ZNF417	physical	25416956
ZMAT2_HUMAN	ZMAT2	physical	25416956
CC112_HUMAN	CCDC112	physical	25416956
TEANC_HUMAN	TCEANC	physical	25416956
PPR18_HUMAN	PPP1R18	physical	25416956
ZBT38_HUMAN	ZBTB38	physical	25416956
KANL1_HUMAN	KANSL1	physical	25416956

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.